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Choroidal neovascularisation secondary to Best’s disease in a 13-year-old boy treated by intravitreal bevacizumab

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Abstract

Background

To describe the effect of intravitreal bevacizumab for the treatment of choroidal neovascularisation secondary to vitelliform dystrophy of the macula (Best’s disease).

Methods

A 13-year-old boy with confirmed Best’s disease presented with visual acuity (VA) loss due to secondary choroidal neovascularisation (CNV). He was treated with a single injection of 1-mg bevacizumab.

Results

Best corrected VA (Snellen) fully recovered from 20/40 preoperatively to 20/20 over a period of 6 months. Optical coherence tomography (OCT) and angiography demonstrated regression of the CNV and resolution of the macular edema.

Conclusions

A single intravitreal injection of bevacizumab may be effective to induce morphologic and functional improvement in a juvenile suffering from CNV secondary to Best’s disease.

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Authors and Affiliations

  1. Department of Ophthalmology, Cologne Hospitals, Cologne, Germany

    Jörg Leu, Norbert F. Schrage & Robert F. Degenring

Authors
  1. Jörg Leu
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  2. Norbert F. Schrage
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  3. Robert F. Degenring
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Corresponding author

Correspondence to Robert F. Degenring.

Additional information

Proprietary interest: none for all authors

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Leu, J., Schrage, N.F. & Degenring, R.F. Choroidal neovascularisation secondary to Best’s disease in a 13-year-old boy treated by intravitreal bevacizumab. Graefes Arch Clin Exp Ophthalmol 245, 1723–1725 (2007). https://doi.org/10.1007/s00417-007-0604-7

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  • DOI: https://doi.org/10.1007/s00417-007-0604-7

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