Abstract
Purpose
To report on the use of intravitreal triamcinolone acetonide as treatment for nonarteritic anterior ischemic optic neuropathy (NAION).
Methods
The interventional clinical case series included three patients with acute NAION who received an intravitreal injection of about 20 mg triamcinolone acetonide.
Results
At the end of follow-up at 3 months, 3.5 months and at 5 months after the injection, visual acuity had changed from 0.10 at baseline to 0.20 in the first patient, from 0.50 to 0.20 in the second patient, and from 0.16 to 0.20 in the third patient. One eye developed triamcinolone-induced ocular hypertension which was treated by topical antiglaucomatous medication.
Conclusions
The clinical courses of all three patients presented suggest that an intravitreal high-dosage injection of triamcinolone acetonide may not be markedly effective in increasing visual acuity after acute NAION.
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References
Al-Haddad CE, Jurdi FA, Bashshur ZF (2004) Intravitreal triamcinolone acetonide for the management of diabetic papillopathy. Am J Ophthalmol 137:1151–1153
Beck RW, Savino PJ, Repka MX, Schatz NJ, Sergott RC (1984) Optic disc structure in anterior ischemic optic neuropathy. Ophthalmology 91:1334–1337
Beck RW, Hayreh SS, Podhajsky PA, Tan ES, Moke PS (1997) Aspirin therapy in nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol 123:212–217
Hayreh SS, Joos KM, Podhajsky PA, Long CR (1994) Systemic diseases associated with non-arteritic anterior ischemic optic neuropathy. Am J Ophthalmol 118:766–780
Jonas JB, Kreissig I, Söfker A, Degenring RF (2003) Intravitreal injection of triamcinolone acetonide for diabetic macular edema. Arch Ophthalmol 121:57–61
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Jonas, J.B., Spandau, U.H., Harder, B. et al. Intravitreal triamcinolone acetonide for treatment of acute nonarteritic anterior ischemic optic neuropathy. Graefe's Arch Clin Exp Ophthalmol 245, 749–750 (2007). https://doi.org/10.1007/s00417-006-0332-4
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DOI: https://doi.org/10.1007/s00417-006-0332-4