Abstract
Background
To describe a case of reactive lymphoid hyperplasia following laser assisted in situ keratomileusis (LASIK).
Methods
This observational case report describes a 31-year-old man who underwent LASIK and presented 1 month later with a fleshy, conjunctival (plical) tumour in the left eye. An excisional biopsy of the tumour was performed.
Results
Histopathology of the excised tumour revealed reactive lymphoid hyperplasia involving the left conjunctiva.
Discussion
Conjunctival lymphomas can masquerade as chronic conjunctivitis and can be preceded by reactive lymphoid hyperplasia. It is important to identify and differentiate these tumours. This report describes the unusual occurrence of a lymphoid conjunctival tumour after LASIK eye surgery.
Similar content being viewed by others
References
Coupland SE, Krause L, Delecluse HJ et al (1998) Lymphoproliferative lesions of the ocular adnexa. Analysis of 112 cases. Ophthalmology 105:1430–1441
Davis E, Hardten D, Lindstrom R (2000) LASIK complications. Int Ophthalmol Clin 40:67–75
Lee D, Sohn H, Park S, Kang Y (2001) Bilateral conjunctival mucosa-associated lymphoid tissue lymphoma misdiagnosed as allergic conjunctivitis. Cornea 20:427–429
Mannami T, Yoshino T, Oshima K et al (2001) Clinical, histopathological and immunogenetic analysis of ocular adnexal lymphoproliferative disorders: characterization of malt lymphoma and reactive lymphoid hyperplasia. Mod Pathol 14:641–649
Ruiz-Morino JM, Alio JL (2003) Incidence of retinal disease following refractive surgery in 9,239 eyes. J Refr Surg 19:534–547
Sharara N, Holden JT, Wojno TH, Feinberg AS, Grossniklaus HE (2003) Adnexal lymphoid proliferations: clinical, histologic, flow cytometric, and molecular analysis of forty-three cases. Ophthalmology 110:1245–1254
Takada S, Yoshino T, Taniwaki M et al (2000) Involvement of the chromosomal translocation t (11:18) in some mucosa-associated lymphoid tissue lymphomas and diffuse large B-cell lymphomas of the ocular adnexa. Mod Path 16:445–452
Weiss H, Rubinfeld R, Anderschat J (2001) LASIK-associated visual field loss in a glaucoma suspect. Arch Ophthalmol 119:774–775
Wotherspoon AC, Diss TC, Pan LX et al (1993) Primary low grade B-cell lymphoma of the conjunctiva: a mucosa-associated lymphoid type lymphoma. Histopathology 23:417–424
Yeung L, Tsao Y, Chen P, Kuo T, Lin K, Lai L (2004) Combination of adult inclusion conjunctivitis and mucosa-associated lymphoid tissue (MALT) lymphoma in a young adult. Cornea 23:7
Acknowledgements
We thank Drs. Steven A. McCormick and Madhavi Kurli for their help with histopathologic analysis, data acquisition, drafting and revision of the manuscript. This research was supported by The EyeCare Foundation, Inc. and Research to Prevent Blindness, New York, USA.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Reddy, S., Finger, P.T., Chynn, E.W. et al. Reactive lymphoid hyperplasia one month after LASIK surgery. Graefe's Arch Clin Exp Ophthalmo 244, 529–531 (2006). https://doi.org/10.1007/s00417-005-0132-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00417-005-0132-2