Skip to main content

Advertisement

SpringerLink
Log in

Radiotherapy in ophthalmology

2004 Jules Gonin Lecture of the Retina Research Foundation

  • Society News
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Abramson DH (1999) Second nonocular cancers in retinoblastoma: a unified hypothesis. The Franceschetti Lecture. Ophthalmic Genet 20:193–204

    Article  PubMed  CAS  Google Scholar 

  2. Abramson DH, Ellsworth RM, Kitchin FD, Tung G (1984) Second nonocular tumors in retinoblastoma survivors. Are they radiation-induced? Ophthalmology 91:1351–1355

    PubMed  CAS  Google Scholar 

  3. Amendola BE, Lamm FR, Markoe AM, Karlsson UL, Shields J, Shields CL, Augsburger J, Brady LW, Woodleigh R, Miller C (1990) Radiotherapy of retinoblastoma. A review of 63 children treated with different irradiation techniques. Cancer 66:21–26

    Article  PubMed  CAS  Google Scholar 

  4. Amman E (1906) Zur Wirkung der Röntgenstrahlen auf das menschliche Auge. Corr-Blatt Schweizer Aerzte 36:487–493

    Google Scholar 

  5. Astrahan MA, Luxton G, Jozsef G, Kampp TD, Liggett PE, Sapozink MD, Petrovich Z (1990) An interactive treatment planning system for ophthalmic plaque radiotherapy. Int J Radiat Oncol Biol Phys 18:679–687

    PubMed  CAS  Google Scholar 

  6. Astrahan MA, Luxton G, Jozsef G, Liggett PE, Petrovich Z (1990) Optimization of 125I ophthalmic plaque brachytherapy. Med Phys 17:1053–1057

    Article  PubMed  CAS  Google Scholar 

  7. Axenfeld T (1914) Doppelseitiges Glioma retinae und intraokulare Strahlentherapie. Klin Monatsbl Augenheilkd 52:426–428

    Google Scholar 

  8. Axenfeld TKLWO (1915) Glioma retinae und intraokulare Strahlentherapie. Klin Monatsbl Augenheilkd 54:61–81

    Google Scholar 

  9. Balmer A, Munier F, Desjardins L (2000) Rétinoblastome. Traitement. In: Zografos L (ed) Tumeurs intraoculaires. Masson, Paris, pp 587–617

    Google Scholar 

  10. Balmer A, Munier F, Zografos L (2003) 100e anniversaire du premier traitement d'un rétinoblastome par irradiation (Hilgartner, 1903). J Fr Ophtalmol 26:1089–1096

    PubMed  CAS  Google Scholar 

  11. Bellmann C, Fuss M, Holz FG, Debus J, Rohrschneider K, Volcker HE, Wannenmacher M (2000) Stereotactic radiation therapy for malignant choroidal tumors: preliminary, short-term results. Ophthalmology 107:358–365

    Article  PubMed  CAS  Google Scholar 

  12. Bornfeld N, Alberti W, Foerster MH, Gerke E, Wessing A, Meyer-Schwickerath G (1983) External beam therapy of choroidal melanomata. Preliminary report. Trans Ophthalmol Soc U K 103(Pt 1):68–71

    PubMed  Google Scholar 

  13. Brovkina AF, Zarubei GD (1986) Ciliochoroidal melanomas treated with a narrow medical proton beam. Arch Ophthalmol 104:402–404

    PubMed  CAS  Google Scholar 

  14. Campinchi R, Lemerle J, Bloch-Michel E, Pinget T, Schweisguth O, Luker P, Schlienger E, Chassagne A, Barret F (1976) La chimiothérapie a-t-elle une place dans le traitement du rétinoblastome ? Bull Soc Ophtalmol Fr 76:17–22

    PubMed  CAS  Google Scholar 

  15. Cassady JR (2000) Radiation therapy and chemotherapy for retinoblastoma: current status. In: Albert DM, Jakobiec FA (eds) Principles and practice of ophthalmology. W.B. Saunders Company, Philadelphia, pp 5102–5116

    Google Scholar 

  16. Ceha HM, van Tienhoven G, Gouma DJ, Veenhof CH, Schneider CJ, Rauws EA, Phoa SS, Gonzalez GD (2000) Feasibility and efficacy of high dose conformal radiotherapy for patients with locally advanced pancreatic carcinoma. Cancer 89:2222–2229

    Article  PubMed  CAS  Google Scholar 

  17. Char DH, Castro JR (1982) Helium ion therapy for choroidal melanoma. Arch Ophthalmol 100:935–938

    PubMed  CAS  Google Scholar 

  18. Coucke PA, Schmid C, Balmer A, Mirimanoff RO, Thames HD (1993) Hypofractionation in retinoblastoma: an increased risk of retinopathy. Radiother Oncol 28:157–161

    Article  PubMed  CAS  Google Scholar 

  19. Desjardins L, Levy C, Labib A, Schlienger P, Putterman M, Zucker JM, Rosenwald JC, Haye C, Validire P (1993) An experience of the use of radioactive plaques after failure of external beam radiation in the treatment of retinoblastoma. Ophthalmic Paediatr Genet 14:39–42

    Article  PubMed  CAS  Google Scholar 

  20. Deutschmann R (1915) Ueber intraokularen Tumor und Strahlentherapie. Z Augenheilkd 33:206–209

    Google Scholar 

  21. Diener-West M, Earle JD, Fine SL, Hawkins BS, Moy CS, Reynolds SM, Schachat AP, Straatsma BR (2001) The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma, II: characteristics of patients enrolled and not enrolled. COMS Report No. 17. Arch Ophthalmol 119:951–965

    PubMed  CAS  Google Scholar 

  22. Diener-West M, Earle JD, Fine SL, Hawkins BS, Moy CS, Reynolds SM, Schachat AP, Straatsma BR (2001) The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma, III: initial mortality findings. COMS Report No. 18. Arch Ophthalmol 119:969–982

    PubMed  CAS  Google Scholar 

  23. Duncan R (1918) Glioma of retina, with report of three cases treated with radium. Am J Ophthalmol 1:715–719

    Google Scholar 

  24. Earle J, Kline RW, Robertson DM (1987) Selection of iodine 125 for the Collaborative Ocular Melanoma Study. Arch Ophthalmol 105:763–764

    PubMed  CAS  Google Scholar 

  25. Ellsworth RM (1968) The treatment of retinoblastoma. Bibl Ophthalmol 75:142–148

    PubMed  CAS  Google Scholar 

  26. Finger PT, Lu D, Buffa A, DeBlasio DS, Bosworth JL (1993) Palladium-103 versus iodine-125 for ophthalmic plaque radiotherapy. Int J Radiat Oncol Biol Phys 27:849–854

    PubMed  CAS  Google Scholar 

  27. Finger PT, Moshfeghi DM, Ho TK (1991) Palladium 103 ophthalmic plaque radiotherapy. Arch Ophthalmol 109:1610–1613

    PubMed  CAS  Google Scholar 

  28. Fontanesi J, Meyer D, Xu S, Tai D (1993) Treatment of choroidal melanoma with I-125 plaque. Int J Radiat Oncol Biol Phys 26:619–623

    PubMed  CAS  Google Scholar 

  29. Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP (1986) A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323:643–646

    Article  PubMed  CAS  Google Scholar 

  30. Gallie BL, Budning A, DeBoer G, Thiessen JJ, Koren G, Verjee Z, Ling V, Chan HS (1996) Chemotherapy with focal therapy can cure intraocular retinoblastoma without radiotherapy. Arch Ophthalmol 114:1321–1328

    PubMed  CAS  Google Scholar 

  31. Goitein M, Miller T (1983) Planning proton therapy of the eye. Med Phys 10:275–283

    Article  PubMed  CAS  Google Scholar 

  32. Gragoudas ES, Goitein M, Koehler A, Constable IJ, Wagner MS, Verhey L, Tepper J, Suit HD, Brockhurst RJ, Schneider RJ, Johnson KN (1978) Proton irradiation of choroidal melanomas: preliminary results. Arch Ophthalmol 96:1583–1591

    Google Scholar 

  33. Gragoudas ES, Zakov NZ, Albert DM, Constable IJ (1979) Long-term observations of proton-irradiated monkey eyes. Arch Ophthalmol 97:2184–2191

    PubMed  CAS  Google Scholar 

  34. Harbour JW, Char DH, Kroll S, Quivey JM, Castro J (1997) Metastatic risk for distinct patterns of postirradiation local recurrence of posterior uveal melanoma [+ discussion]. Ophthalmology 104:1785–1793

    PubMed  CAS  Google Scholar 

  35. Hernandez JC, Brady LW, Shields JA, Shields CL, DePotter P, Karlsson UL, Markoe AM, Amendola BE, Singh A (1996) External beam radiation for retinoblastoma: results, patterns of failure, and a proposal for treatment guidelines. Int J Radiat Oncol Biol Phys 35:125–132

    PubMed  CAS  Google Scholar 

  36. Hilaris BS, Holt GS, St.Germain J (1975) The use of iodine-125 for interstitial implants, vol. 76. Department of Health, Education and Welfare, Rockville MD

    Google Scholar 

  37. Hilgartner HL (1903) Report of case of double glioma treated with X-ray. Tex Med J 18:322–323

    Google Scholar 

  38. Höpping W (1966) Die Therapie des Retinoblastoms. In: François J (ed) Die Tumoren des Auges und seiner Adnexe. 2. Kongress der Europäischen Gesellschaft für Ophthalmologie, Wien, 1964. Karger, Basel

    Google Scholar 

  39. Hungerford JL, Toma NM, Plowman PN, Kingston JE (1995) External beam radiotherapy for retinoblastoma: I. Whole eye technique. Br J Ophthalmol 79:109–111

    Article  PubMed  CAS  Google Scholar 

  40. Innes GS (1964) The application of physics in the treatment of ocular neoplasms. In: Boniuk M (ed) Ocular and adnexal tumors, new and controversial aspects. Mosby, St. Louis, pp 142–157

    Google Scholar 

  41. Jampol LM, Moy CS, Murray TG, Reynolds SM, Albert DM, Schachat AP, Diddie KR, Engstrom RE Jr, Finger PT, Hovland KR, Joffe L, Olsen KR, Wells CG (2002) The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma: IV. Local treatment failure and enucleation in the first 5 years after brachytherapy. COMS report no. 19. Ophthalmology 109:2197–2206

    Article  PubMed  Google Scholar 

  42. Janeway HH (1920) The therapeutic use of radium in disease of the eye. Arch Ophthalmol 49:156–174

    Google Scholar 

  43. Jendralsky F (1920) Radiotherapeutische Erfahrungen bei Tumoren und Tuberkulose des Auges und seiner Umgebung. Klin Monatsbl Augenheilkd 65:565–573

    Google Scholar 

  44. Kepka AG, Johnson PM, Kline RW (1988) The generalized geometry of eye plaque therapy. Med Phys 15:375–379

    Article  PubMed  CAS  Google Scholar 

  45. Kerst DW (1943) The betatron. Radiology 40:115–119

    CAS  Google Scholar 

  46. Kupfer C (1953) Retinoblastoma treated with intravenous nitrogen mustard. Am J Ophthalmol 36:1721–1723

    PubMed  CAS  Google Scholar 

  47. Langmann G, Pendl G, Schröttner O, Stücklschweiger G, Faulborn J (1995) Die radiochirurgische Therapie mit der Leksell Gamma Einheit in der Behandlung von Aderhautmelanomen. Spektrum Augenheilkd 9:16–21

    Article  Google Scholar 

  48. Lee AG, Woo SY, Miller NR, Safran AB, Grant WH, Butler EB (1996) Improvement in visual function in an eye with a presumed optic nerve sheath meningioma after treatment with three-dimensional conformal radiation therapy. J Neuroophthalmol 16:247–251

    PubMed  CAS  Google Scholar 

  49. Levy C, Doz F, Quintana E, Pacquement H, Michon J, Schlienger P, Validire P, Asselain B, Desjardins L, Zucker JM (1998) Role of chemotherapy alone or in combination with hyperthermia in the primary treatment of intraocular retinoblastoma: preliminary results. Br J Ophthalmol 82:1154–1158

    PubMed  CAS  Google Scholar 

  50. Leyvraz S, Spataro V, Bauer J, Pampallona S, Salmon R, Dorval T, Meuli R, Gillet M, Lejeune F, Zografos L (1997) Treatment of ocular melanoma metastatic to the liver by hepatic arterial chemotherapy. J Clin Oncol 15:2589–2595

    PubMed  CAS  Google Scholar 

  51. Lommatzsch P (1968) Morphologische und funktionnelle Veränderungen des Kaninchenauges nach Einwirkung von Betastrahlen (106Ru/106Rh) auf des dorsalen Bulbusabschnitt. Graefes Arch Ophthalmol 176:100–125

    CAS  Google Scholar 

  52. Lommatzsch P (1970) Die Anwendung von Bestrahlen mit 106Ru/106Rh-Applikatoren bei der Behandlung des Retinoblastoms. Klin Monatsbl Augenheilkd 156:662–669

    PubMed  CAS  Google Scholar 

  53. Lommatzsch PK, Werschnik C, Schuster E (2000) Long-term follow-up of Ru-106/Rh-106 brachytherapy for posterior uveal melanoma. Graefes Arch Clin Exp Ophthalmol 238:129–137

    Article  PubMed  CAS  Google Scholar 

  54. Martin HE, Reese AB (1936) the treatment of retinal gliomas by the fractionated or divided dose principle of roentgen radiation. Arch Ophthalmol 16:733–761

    Google Scholar 

  55. Martin HE, Reese AB (1940) The treatment of retinoblastoma (retinal glioma) by a combination of surgery and radiation. Trans Am Acad Ophthalmol Otolaryngol 45:70–97

    Google Scholar 

  56. Martin HE, Reese AB (1945) Treatment of bilateral retinoblastoma (retinal glioma) surgically and by irradiation. Arch Ophthalmol 33:429–439

    Google Scholar 

  57. Marx E (1922) Over diagnose en behandeling van het glioma retinae. Nederl Tijd Geneesk 66:683–690

    Google Scholar 

  58. Miller CW (1953) Travelling-wave linear accelerator for X ray therapy. Nature 171:297–298

    Article  PubMed  CAS  Google Scholar 

  59. Moore RF (1930) Choroidal sarcoma treated by the intraocular insertion of radons seeds. Br J Ophthalmol 14:145–152

    Article  PubMed  CAS  Google Scholar 

  60. Moore RF, Stallard HBMJG (1931) Retinal glioma treated by radon seeds. Br J Ophthalmol 15:673–696

    Article  PubMed  CAS  Google Scholar 

  61. Mukai S (1993) Management of retinoblastoma. Sem Ophthalmol 8:281–291

    Article  Google Scholar 

  62. Mukai SMJE, Tarbell N (2001) Proton radiotherapy in intraocular retinoblastoma after chemotherapy. Xth International Symposium on Retinoblastoma. Fort Lauderdale, Florida

    Google Scholar 

  63. Murphree AL, Villablanca JG, Deegan WF III, Sato JK, Malogolowkin M, Fisher A, Parker R, Reed E, Gomer CJ (1996) Chemotherapy plus local treatment in the management of intraocular retinoblastoma. Arch Ophthalmol 114:1348–1356

    PubMed  CAS  Google Scholar 

  64. Nenadov Beck M, Balmer A, Dessing C, Pica A, Munier F (2000) First-line chemotherapy with local treatment can prevent external-beam irradiation and enucleation in low-stage intraocular retinoblastoma. J Clin Oncol 18:2881–2887

    Google Scholar 

  65. Pedroni E, Bacher R, Blattmann H, Bohringer T, Coray A, Lomax A, Lin S, Munkel G, Scheib S, Schneider U (1995) The 200-MeV proton therapy project at the Paul Scherrer Institute: conceptual design and practical realization. Med Phys 22:37–53

    Article  PubMed  CAS  Google Scholar 

  66. Pedroni E, Scheib S, Bohringer T, Coray A, Grossmann M, Lin S, Lomax A (2005) Experimental characterization and physical modelling of the dose distribution of scanned proton pencil beams. Phys Med Biol 50:541–561

    Article  PubMed  CAS  Google Scholar 

  67. Perret C (1987) The therapy planning program EYE. Villigen internal report TM—61-016. Paul Scherrer Institut (PSI)

  68. Puusaari I, Heikkonen J, Summanen P, Tarkkanen A, Kivela T (2003) Iodine brachytherapy as an alternative to enucleation for large uveal melanomas. Ophthalmology 110:2223–2234

    Article  PubMed  Google Scholar 

  69. Reese AB, Merriam GR, Martin HE (1949) Treatment of bilateral retinoblastoma therapy. Am J Ophthalmol 32:175–190

    PubMed  CAS  Google Scholar 

  70. Rotman M, Long RS, Chan B, Galin M, Moroson H (1976) Radiation therapy of choroidal melanoma. Proc. 2nd Int. Symposium Radiation Therapy, 1975, Cancer Memorial, pp 133–139

  71. Schipper J (1983) An accurate and simple method for megavoltage radiation therapy of retinoblastoma. Radiother Oncol 1:31–41

    Article  PubMed  CAS  Google Scholar 

  72. Schoenberg MJ (1919) A case of bilateral glioma of the retina apparently arrested in the non-enucleated eye by radium treatment. Arch Ophthalmol 48:485–488

    Google Scholar 

  73. Sealy R, le Roux PL, Rapley F, Hering E, Shackleton D, Sevel D (1976) The treatment of ophthalmic tumours with low-energy sources. Br J Radiol 49:551–554

    Article  PubMed  CAS  Google Scholar 

  74. Sheen M (1995) Eye plan proton therapy planning program. Internal report Douglas Cyclotron Unit. Center for Oncology, Clattebridge

  75. Shields CL, De Potter P, Himelstein BP, Shields JA, Meadows AT, Maris JM (1996) Chemoreduction in the initial management of intraocular retinoblastoma. Arch Ophthalmol 114:1330–1338

    PubMed  CAS  Google Scholar 

  76. Shields CL, Shields JA, Cater J, Othmane I, Singh AD, Micaily B (2001) Plaque radiotherapy for retinoblastoma: long-term tumor control and treatment complications in 208 tumors. Ophthalmology 108:2116–2121

    Article  PubMed  CAS  Google Scholar 

  77. Shields CL, Shields JA, De Potter P, Hernandez C, Brady LW (1993) Plaque radiotherapy for retinoblastoma. Int Ophthalmol Clin 33:107–118

    Article  PubMed  CAS  Google Scholar 

  78. Shields JA, Shields CL, De Potter P, Hernandez JC, Brady LW (1994) Plaque radiotherapy for residual or recurrent retinoblastoma in 91 cases. J Pediatr Ophthalmol Strabismus 31:242–245

    PubMed  CAS  Google Scholar 

  79. Stallard HB (1933) Radiant energy as a) a pathogenic, b) a therapeutic agent in ophthalmic disorders. Br J Ophthalmol Monogr Suppl 6

  80. Stallard HB (1938) A new technique for the application of radon seeds to the sclera in the treatment of glioma retinae. Br J Ophthalmol 22:604–608

    Article  PubMed  CAS  Google Scholar 

  81. Stallard HB (1952) Comparative value of radium and deep X rays in the treatment of retinoblastoma. Br J Ophthalmol 36:313–324

    Article  PubMed  CAS  Google Scholar 

  82. Stallard HB (1952) The use of radium discs in the treatment of malignant intraocular neoplasms. Trans Ophthalmol Soc UK 72:417–418

    Google Scholar 

  83. Stallard HB (1954) Pathological study of retinoblastoma treated by radon seeds and radium disks. Arch Ophthalmol 51:573–588

    CAS  Google Scholar 

  84. Stallard HB (1966) Radiotherapy for malignant melanoma of the choroid. Br J Ophthalmol 50:147–155

    Article  PubMed  CAS  Google Scholar 

  85. Stallard HB (1968) Malignant melanoblastoma of the choroid. Bibl Ophthalmol 75:16–38

    PubMed  CAS  Google Scholar 

  86. Stallard HB (1968) The treatment of retinoblastoma. Bibl Ophthalmol 75:149–173

    PubMed  CAS  Google Scholar 

  87. Summanen P, Immonen I, Heikkonen J, Tommila P, Laatikainen L, Tarkkanen A (1993) Survival of patients and metastatic and local recurrent tumor growth in malignant melanoma of the uvea after ruthenium plaque radiotherapy. Ophthalmic Surg 24:82–90

    PubMed  CAS  Google Scholar 

  88. Teh BS, Mai WY, Augspurger ME, Uhl BM, McGary J, Dong L, Grant WH III, Lu HH, Woo SY, Carpenter LS, Chiu JK, Butler EB (2001) Intensity modulated radiation therapy (IMRT) following prostatectomy: more favorable acute genitourinary toxicity profile compared to primary IMRT for prostate cancer. Int J Radiat Oncol Biol Phys 49:465–472

    Article  PubMed  CAS  Google Scholar 

  89. Toma NM, Hungerford JL, Plowman PN, Kingston JE, Doughty D (1995) External beam radiotherapy for retinoblastoma: II. Lens sparing technique. Br J Ophthalmol 79:112–117

    Article  PubMed  CAS  Google Scholar 

  90. Verhoeff FH (1921) Glioma retinae treated by X-rays with apparent destruction of the tumor and preservation of normal vision. Arch Ophthalmol 50:450–456

    Google Scholar 

  91. Vijayakumar S, Chen GT (1995) Implementation of three dimensional conformal radiation therapy: prospects, opportunities, and challenges. Int J Radiat Oncol Biol Phys 33:979–983

    PubMed  CAS  Google Scholar 

  92. Wilson MW, Hungerford JL (1999) Comparison of episcleral plaque and proton beam radiation therapy for the treatment of choroidal melanoma. Ophthalmology 106:1579–1587

    Article  PubMed  CAS  Google Scholar 

  93. Zehetmayer M, Dieckmann K, Kren G, Kitz K, Ruhswurm I, Georgopoulos M, Potter R (1999) Fractionated stereotactic radiotherapy with linear accelerator for uveal melanoma–preliminary Vienna results. Strahlenther Onkol 175(Suppl 2):74–75

    Article  PubMed  Google Scholar 

  94. Zehetmayer M, Menapace R, Kitz K, Ertl A (1994) Suction attachment for stereotactic radiosurgery of intraocular malignancies. Ophthalmologica 208:119–121

    Article  PubMed  CAS  Google Scholar 

  95. Zimmerman LE, McLean IW, Foster WD (1978) Does enucleation of the eye containing a malignant melanoma prevent or accelerate the dissemination of tumour cells. Br J Ophthalmol 62:420–425

    Article  PubMed  CAS  Google Scholar 

  96. Zografos L (2002) Techniques thérapeutiques. In: Zografos L (ed) Tumeurs Intraoculaires. Masson, Paris, pp 21–64

    Google Scholar 

  97. Zografos L, Bercher L, Egger E, Chamot L, Gailloud C, Uffer S, Perret C, Markovits C (1992) Le traitement des tumeurs oculaires par faisceau de protons accélérés: 7 ans d'expérience. Klin Monatsbl Augenheilkd 200:431–435

    Article  PubMed  CAS  Google Scholar 

  98. Zografos L, Desjardins L, Uffer S, Egger E (2002) Traitement conservateur des mélanomes. In: Zografos L (ed) Tumeurs Intraoculaires. Masson, Paris, pp 243–279

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. University Eye Clinic—Jules Gonin Hospital, Lausanne, Switzerland

    Leonidas Zografos

Authors
  1. Leonidas Zografos
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Leonidas Zografos.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zografos, L. Radiotherapy in ophthalmology. Graefe's Arch Clin Exp Ophthalmo 244, 895–906 (2006). https://doi.org/10.1007/s00417-005-0120-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00417-005-0120-6

Search

Navigation