Abstract
The 9139 follow-up records of 438 myasthenia gravis (MG) patients were reviewed. Excluding those patients who were diagnosed 5 or more years after symptom onset (n = 37) and those who experienced only oculomotor symptoms throughout follow-up (n = 21), there were 380 patients. A survival analysis approach was used to assess the influence of prognostic factors on the following endpoints: (a) stable complete remission, (b) complete remission of at least 6 months and (c) pharmacological remission of at least 6 months. Early diagnosis was associated with a better prognosis with respect to all endpoints. Thymectomy also improved the prognosis but only for those patients without thymoma. Later MG onset was associated with a higher tendency to achieve pharmacological remission.
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Received: 27 October 1994 Received in revised form: 30 June 1997 Accepted: 10 July 1997
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Cosi, V., Romani, A., Lombardi, M. et al. Prognosis of myasthenia gravis: a retrospective study of 380 patients. J Neurol 244, 548–555 (1997). https://doi.org/10.1007/s004150050142
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DOI: https://doi.org/10.1007/s004150050142