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Adult-onset ataxia or developmental disorder with seizures: two sides of missense changes in CACNA1A

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References

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Acknowledgements

This work was supported by the German Ministry of Education and Research (BMBF, DYSTRACT consortium, 01GM1514B, to KL, AM), the Foundation of the University Medical Center Schleswig–Holstein “Gutes Tun!” (AM) and the Possehl-Stiftung (Lübeck, AM).

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Author notes

  1. Alexander Balck and Henrike Hanßen contributed equally to the paper.

Authors and Affiliations

  1. Institute of Neurogenetics, University of Lübeck, Lübeck, Germany

    Alexander Balck, Henrike Hanssen, Katja Lohmann & Alexander Münchau

  2. Department of Neurology, University Hospital Schleswig-Holstein, Lübeck, Germany

    Henrike Hanssen

  3. Institute of Human Genetics, University of Lübeck, Lübeck, Germany

    Yorck Hellenbroich

Authors
  1. Alexander Balck
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  2. Henrike Hanssen
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  3. Yorck Hellenbroich
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  4. Katja Lohmann
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  5. Alexander Münchau
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Corresponding author

Correspondence to Alexander Münchau.

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Conflicts of interest

The authors have no disclosures relevant to the manuscript.

Financial relations

Katja Lohmann has been receiving grants from the German Research Foundation (DFG) and the German Federal Ministry of Education and Research (BMBF, DYSTRACT consortium). Alexander Münchau: Commercial research support by Pharm Allergan, Ipsen, Merz Pharmaceuticals, Actelion; Honoraria for lectures from Pharm Allergan, Ipsen, Merz Pharmaceuticals, Actelion, GlaxoSmithKline, Desitin and Teva. Support from the Possehl-Stiftung, Lübeck; the Margot und Jürgen Wessel Stiftung, Lübeck; Tourette Syndrome Association (Germany); European Huntington Disease Network; Academic research support: Multicentre Tics in Children Studies (EMTICS) as part of the FP 7 program (HEALTH.2011.2.2.1-3); Deutsche Forschungsgemeinschaft (DFG): Projects 1692/3-1, 4-1, SFB 936; Bundesministerium für Bildung und Forschung (BMBF): DysTract consortium. Innovationsausschuss of the Gemeinsamer Bundesausschuss: Translate NAMSE (structural support for the Lübeck Center for Rare Diseases); Royalties from the publication of the book Neurogenetics (Oxford University Press).

Ethical standards

Ethical approval for this study was obtained from the local ethics committee (Ref. 11-021).

Informed consent

informed consent was obtained from each involved patient.

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Balck, A., Hanssen, H., Hellenbroich, Y. et al. Adult-onset ataxia or developmental disorder with seizures: two sides of missense changes in CACNA1A. J Neurol 264, 1520–1522 (2017). https://doi.org/10.1007/s00415-017-8494-z

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  • DOI: https://doi.org/10.1007/s00415-017-8494-z

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