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Inverse eye position dependency of downbeat nystagmus in midline medullary lesion

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References

  1. Bertholon P, Convers P, Barral FG, Duthel R, Michel D (1993) Post-traumatic syringomyelobulbia and inferior vertical nystagmus. Revue Neurologique 149:355–358

    PubMed  CAS  Google Scholar 

  2. Buttner-Ennever JA, Horn AK (1996) Pathways from cell groups of the paramedian tracts to the floccular region. Ann N Y Acad Sci 781:532–540

    Article  PubMed  CAS  Google Scholar 

  3. Glasauer S, Hoshi M, Kempermann U, Eggert T, Buttner U (2003) Three-dimensional eye position and slow phase velocity in humans with downbeat nystagmus. J Neurophysiol 89:338–354

    Article  PubMed  CAS  Google Scholar 

  4. Helmchen C, Sprenger A, Rambold H, Sander T, Kompf D, Straumann D (2004) Effect of 3,4-diaminopyridine on the gravity dependence of ocular drift in downbeat nystagmus. Neurology 63:752–753

    Article  PubMed  CAS  Google Scholar 

  5. Marti S, Straumann D, Buttner U, Glasauer S (2008) A model-based theory on the origin of downbeat nystagmus. Exp Brain Res 188:613–631

    Article  PubMed  Google Scholar 

  6. Nakamagoe K, Fujizuka N, Koganezawa T, Yamaguchi T, Tamaoka A (2013) Downbeat nystagmus associated with damage to the medial longitudinal fasciculus of the pons: a vestibular balance control mechanism via the lower brainstem paramedian tract neurons. J Neurol Sci 328:98–101

    Article  PubMed  Google Scholar 

  7. Nakamagoe K, Iwamoto Y, Yoshida K (2000) Evidence for brainstem structures participating in oculomotor integration. Science 288:857–859

    Article  PubMed  CAS  Google Scholar 

  8. Nakamagoe K, Shimizu K, Koganezawa T, Tamaoka A (2012) Downbeat nystagmus due to a paramedian medullary lesion. J Clin Neurosci 19:1597–1599

    Article  PubMed  Google Scholar 

  9. Sander T, Sprenger A, Marti S, Naumann T, Straumann D, Helmchen C (2011) Effect of 4-aminopyridine on gravity dependence and neural integrator function in patients with idiopathic downbeat nystagmus. J Neurol 258:618–622

    Article  PubMed  CAS  Google Scholar 

  10. Schaltenbrand G, Wahren W (1977) Atlas for Stereotaxy of the Human Brain. Thieme Stuttgart New York

  11. Straumann D, Zee DS, Solomon D (2000) Three-dimensional kinematics of ocular drift in humans with cerebellar atrophy. J Neurophysiol 83:1125–1140

    PubMed  CAS  Google Scholar 

  12. Wagner J, Lehnen N, Glasauer S, Rettinger N, Buttner U, Brandt T, Strupp M (2009) Downbeat nystagmus caused by a paramedian ponto-medullary lesion. J Neurol 256:1572–1574

    Article  PubMed  Google Scholar 

  13. Zee DS, Leigh RJ, Mathieu-Millaire F (1980) Cerebellar control of ocular gaze stability. Ann Neurol 7:37–40

    Article  PubMed  CAS  Google Scholar 

  14. Zee DS, Yamazaki A, Butler PH, Gucer G (1981) Effects of ablation of flocculus and paraflocculus of eye movements in primate. J Neurophysiol 46:878–899

    PubMed  CAS  Google Scholar 

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This study has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki.

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Correspondence to Christoph Helmchen.

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Helmchen, C., Glasauer, S. & Sprenger, A. Inverse eye position dependency of downbeat nystagmus in midline medullary lesion. J Neurol 260, 2908–2910 (2013). https://doi.org/10.1007/s00415-013-7147-0

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  • DOI: https://doi.org/10.1007/s00415-013-7147-0

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