Skip to main content

Advertisement

SpringerLink
Log in

Inflammatory demyelinating CNS disorder in a case of X-linked Charcot–Marie–Tooth disease: positive response to natalizumab

  • Letter to the Editors
  • Published:
Journal of Neurology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Zhou L, Griffin JW (2003) Demyelinating neuropathies. Curr Opin Neurol 16(3):307–313

    Article  PubMed  Google Scholar 

  2. Bergoffen J et al (1993) Connexin mutations in X-linked Charcot–Marie–Tooth disease. Science 262(5142):2039–2042

    Article  PubMed  CAS  Google Scholar 

  3. Kleopa KA, Scherer SS (2006) Molecular genetics of X-linked Charcot–Marie–Tooth disease. Neuromolecular Med 8(1–2):107–122

    PubMed  CAS  Google Scholar 

  4. Scherer SS et al (1995) Connexin32 is a myelin-related protein in the PNS and CNS. J Neurosci 15(12):8281–8294

    PubMed  CAS  Google Scholar 

  5. Bahr M et al (1999) Central visual, acoustic, and motor pathway involvement in a Charcot–Marie–Tooth family with an Asn205Ser mutation in the connexin 32 gene. J Neurol Neurosurg Psychiatry 66(2):202–206

    Article  PubMed  CAS  Google Scholar 

  6. Nicholson GA, Yeung L, Corbett A (1998) Efficient neurophysiologic selection of X-linked Charcot–Marie–Tooth families: ten novel mutations. Neurology 51(5):1412–1416

    Article  PubMed  CAS  Google Scholar 

  7. Taylor RA et al (2003) The CNS phenotype of X-linked Charcot–Marie–Tooth disease: more than a peripheral problem. Neurology 61(11):1475–1478

    Article  PubMed  Google Scholar 

  8. Panas M et al (2004) Charcot–Marie–Tooth disease type 1A with central nervous system involvement in two generations. J Neurol 251(4):484–485

    Article  PubMed  CAS  Google Scholar 

  9. Hanemann CO et al (2003) Transient, recurrent, white matter lesions in X-linked Charcot–Marie–Tooth disease with novel connexin 32 mutation. Arch Neurol 60(4):605–609

    Article  PubMed  Google Scholar 

  10. Sargiannidou I et al (2009) Connexin32 mutations cause loss of function in Schwann cells and oligodendrocytes leading to PNS and CNS myelination defects. J Neurosci 29(15):4736–4749

    Article  PubMed  CAS  Google Scholar 

  11. Paulson HL et al (2002) Transient central nervous system white matter abnormality in X-linked Charcot–Marie–Tooth disease. Ann Neurol 52(4):429–434

    Article  PubMed  CAS  Google Scholar 

  12. Isoardo G et al (2005) X-linked Charcot–Marie–Tooth disease and progressive-relapsing central demyelinating disease. Neurology 65(10):1672–1673

    Article  PubMed  CAS  Google Scholar 

  13. Parman Y et al (2007) X-linked Charcot–Marie–Tooth disease and multiple sclerosis. J Neurol 254(7):953–955

    Article  PubMed  CAS  Google Scholar 

  14. Ginsberg L et al (2004) Coexistent hereditary and inflammatory neuropathy. Brain 127(Pt 1):193–202

    Article  PubMed  Google Scholar 

  15. Dyck PJ et al (1982) Prednisone-responsive hereditary motor and sensory neuropathy. Mayo Clin Proc 57(4):239–246

    PubMed  CAS  Google Scholar 

  16. Bird SJ, Sladky JT (1991) Corticosteroid-responsive dominantly inherited neuropathy in childhood. Neurology 41(3):437–439

    Article  PubMed  CAS  Google Scholar 

  17. Oppenheimer DR (1978) The cervical cord in multiple sclerosis. Neuropathol Appl Neurobiol 4(2):151–162

    Article  PubMed  CAS  Google Scholar 

Download references

Conflicts of interest

None.

Author information

Author notes

  1. Jochen H. Weishaupt

    Present address: Neurology Department, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany

Authors and Affiliations

  1. Department of Neurology, University Medical Center Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Germany

    Claudia Ganser

  2. DFG-Research Center for Molecular Physiology of the Brain (CMPB), Humboldtallee 23, Göttingen, Germany

    Jochen H. Weishaupt & Mathias Bähr

Authors
  1. Jochen H. Weishaupt
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Claudia Ganser
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mathias Bähr
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jochen H. Weishaupt.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Weishaupt, J.H., Ganser, C. & Bähr, M. Inflammatory demyelinating CNS disorder in a case of X-linked Charcot–Marie–Tooth disease: positive response to natalizumab. J Neurol 259, 1967–1969 (2012). https://doi.org/10.1007/s00415-012-6467-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00415-012-6467-9

Keywords

Search

Navigation