Skip to main content
SpringerLink
Log in

Response to intravenous immunoglobulins and placebo in a patient with narcolepsy with cataplexy

  • LETTER TO THE EDITORS
  • Published:
Journal of Neurology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Black JL 3rd, Krahn LE, Pankratz VS, Silber M (2002) Search for neuronspecific and nonneuron-specific antibodies in narcoleptic patients with and without HLA DQB1*602. Sleep 25:719–723

    PubMed  Google Scholar 

  2. Dauvilliers Y, Carlander B, Rivier F, Touchon J, Tafti M (2004) Successful management of cataplexy with intravenous immunoglobulins at narcolepsy onset. Ann Neurol 56:905–908

    Article  CAS  PubMed  Google Scholar 

  3. Hecht M, Lin L, Kushida CA, Umetsu DT, Taheri S, Einen M, Mignot E (2003) Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy. Sleep 26:809–810

    PubMed  Google Scholar 

  4. Lecendreux M, Maret S, Bassetti C, Mouren MC, Tafti M (2003) Clinical efficacy of high-dose intravenous immunoglobulins near the onset of narcolepsy in a 10-year-old boy. J Sleep Res 12:347–348

    PubMed  Google Scholar 

  5. Mignot E, Lin L, Rogers W, Honda Y, Qiu X, Lin X, Okun M, Hohjoh H, Miki T, Hsu S, Leffell M, Grumet F, Fernandez-Vina M, Honda M, Risch N (2001) Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. Am J Hum Genet 68:686–699

    Article  CAS  PubMed  Google Scholar 

  6. Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E (2000) Hypocretin (orexin) deficiency in human narcolepsy. Lancet 355:39–40

    Article  CAS  PubMed  Google Scholar 

  7. Overeem S, Verschuuren JJ, Fronczek R, Schreurs L, den Hertog H, Hegeman-Kleinn IM, van Duinen SG, Unmehopa UA, Swaab DF, Lammers GJ (2006) Immunohistochemical screening for autoantibodies against lateral hypothalamic neurons in human narcolepsy. J Neuroimmunol 174:187–191

    Article  CAS  PubMed  Google Scholar 

  8. Peyron C, Faraco J, Rogers W, Ripley B, Overeem S, Charnay Y, Nevsimalova S, Aldrich M, Reynolds D, Albin R, Li R, Hungs M, Pedrazzoli M, Padigaru M, Kucherlapati M, Fan J, Maki R, Lammers GJ, Bouras C, Kucherlapati R, Nishino S, Mignot E (2000) A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 6:991–997

    Article  CAS  PubMed  Google Scholar 

  9. Guyatt G, Sackett D, Taylor DW, Chong J, Roberts R, Pugsley S (1986) Determining optimal therapy–randomized trials in individual patients. N Engl J Med 314(14):889–892

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Leiden University Medical Centre, Dept. of Neurology (K5Q), 9600, 2300 RC, Leiden, The Netherlands

    R. Fronczek MSc, J. Verschuuren MD, Phd & G. J. Lammers MD, PhD

Authors
  1. R. Fronczek MSc
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Verschuuren MD, Phd
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G. J. Lammers MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to G. J. Lammers MD, PhD.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fronczek, R., Verschuuren, J. & Lammers, G.J. Response to intravenous immunoglobulins and placebo in a patient with narcolepsy with cataplexy. J Neurol 254, 1607–1608 (2007). https://doi.org/10.1007/s00415-007-0594-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00415-007-0594-8

Keywords

Search

Navigation