Skip to main content

Advertisement

SpringerLink
Log in

A 45-year history of acquired autoimmune neuromyotonia

  • LETTER TO THE EDITORS
  • Published:
Journal of Neurology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Hart IK, Maddison P, Newsom-Davis J, Vincent A, Mills KR (2002) Phenotypic variants of autoimmune peripheral nerve hyperexcitability. Brain 125:1887–1895

    Article  PubMed  Google Scholar 

  2. Nagado T, Arimura K, Sonoda Y, Kurona A, Horikiri Y, Kamryama A et al. (1999) Potassium current suppression in patients with periperhal nerve hyperexcitability. Brain 122:2057–2066

    Article  PubMed  Google Scholar 

  3. Nakatsuji Y, Kaido M, Sugai F, Nakamori M, Abe K, Watanabe O, Arimura K, Sakoda S (2000) Isaacs’ syndrome successfully treated by immunadsorption plasmapharesis. Acta Neurol Scand 102:271–273

    Article  PubMed  CAS  Google Scholar 

  4. Newsom-Davis J, Mills KR (1993) Immunological associations of acquired neuromyotonia (Isaacs’ syndrome): report of five cases and literature review. Brain 116:453–469

    PubMed  Google Scholar 

  5. Gutmann L, Gutmann L (2004) Myokymia and neuromyotonia 2004. J Neurol 251:138–142

    Article  PubMed  Google Scholar 

  6. Newsom-Davis J, Buckley C, Clover L, Hart I, Maddison P, Tüzüm E, Vincent A (2003) Autoimmune disorders of neuronal potassium channels. Ann NY Acad Sci 998:202–210

    Article  PubMed  CAS  Google Scholar 

  7. Shillito P, Molenaar PC, Vincent A, Leys K, Zheng W, van den Berg KJ et al. (1995) Acquired neuromyotonia: evidence for autoantibodies directed against K+ channels of peripheral nerves. Ann Neurol 38:714–722

    Article  PubMed  CAS  Google Scholar 

  8. Sinha S, Newsom-Davis J, Mills K, Byrne N, Lang B, Vincent A (1991) Autoimmune aetiology for acquired neuromyotonia (Isaacs’ syndrome). Lancet 338:75–77

    Article  PubMed  CAS  Google Scholar 

  9. van den Berg JSP, van Engelen BGM, Boerman RH, de Baets MH (1999) Acquired neuromyotonia: superiority of plasma exchange over high-dose intravenous human immunoglobulin. J Neurol 246:623–625

    Article  PubMed  Google Scholar 

  10. Vincent A, Buckley C, Schott JM, Baker I, Dewar B, Detert N, Clover L, Parkinson A, Bien CG, Omer S, Lang B, Rossor MN, Palace J (2004) Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of limbic encephalitis. Brain 127:701–712

    Article  PubMed  Google Scholar 

Download references

Acknowledgement

We thank Dr. B Murray for helpful discussion in this case.

Author information

Authors and Affiliations

  1. Department of Neurology, Mater Misericordiae University Hospital, Eccles Street, Dublin, Ireland

    Aisling Ryan, Gerard Mullins, Jacqui Scott & Tim Lynch

  2. Department of Neurophysiology, St. Vincent’s University Hospital, Elm Park, Dublin, Ireland

    Sean Connolly

  3. Department of Neurology, Beaumont Hospital, Dublin, Ireland

    Orla Hardiman

  4. Neurosciences Group, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK

    Emrullah Yilmaz & Angela Vincent

Authors
  1. Aisling Ryan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Gerard Mullins
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jacqui Scott
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Sean Connolly
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Orla Hardiman
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Emrullah Yilmaz
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Angela Vincent
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Tim Lynch
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Tim Lynch.

Additional information

Received in revised form: 18 November 2005

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ryan, A., Mullins, G., Scott, J. et al. A 45-year history of acquired autoimmune neuromyotonia. J Neurol 253, 1243–1245 (2006). https://doi.org/10.1007/s00415-006-0172-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00415-006-0172-5

Keywords

Search

Navigation