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Hypocretin-1 (orexin A) levels are normal in Huntington’s disease

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References

  1. Starr A (1967) A disorder of rapid eye movements in Huntington’s chorea. Brain 90:545–564

    PubMed  CAS  Google Scholar 

  2. Brotini S, Gigli GL (2004) Epidemiology and clinical features of sleep disorders in extrapyramidal disease. Sleep Med 5:169–79

    Article  PubMed  Google Scholar 

  3. Wiegand M, Moller AA, Lauer CJ, Stolz S, Schreiber W, Dose M, Krieg JC (1991) Nocturnal sleep in Huntington’s disease. J Neurol 238:203–208

    Article  PubMed  CAS  Google Scholar 

  4. Trejo A, Tarrats RM, Alonso ME, Boll MC, Ochoa A, Velasquez L (2004) Assessment of the nutrition status of patients with Huntington’s disease. Nutrition 20:192–6

    Article  PubMed  CAS  Google Scholar 

  5. Popovic V, Svetel M, Djurovic M, Petrovic S, Doknic M, Pekic S, Miljic D, Milic N, Glodic J, Dieguez C, Casanueva FF, Kostic V (2004) Circulating and cerebrospinal fluid ghrelin and leptin: potential role in altered body weight in Huntington’s disease. Eur J Endocrinol 151:451–5

    Article  PubMed  CAS  Google Scholar 

  6. Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E (2000) Hypocretin (orexin) deficiency in human narcolepsy. Lancet 355:39–40

    Article  PubMed  CAS  Google Scholar 

  7. Peyron C, Faraco J, Rogers W, Ripley B, Overeem S, Charnay Y, Nevsimalova S, Aldrich M, Reynolds D, Albin R, Li R, Hungs M, Pedrazzoli M, Padigaru M, Kucherlapati M, Fan J, Maki R, Lammers GJ, Bouras C, Kucherlapati R, Nishino S, Mignot E (2000) A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 6:991–7

    Article  PubMed  CAS  Google Scholar 

  8. Petersen A, Gil J, Maat-Schieman ML, Bjorkqvist M, Tanila H, Araujo IM, Smith R, Popovic N, Wierup N, Norlen P, Li JY, Roos RA, Sundler F, Mulder H, Brundin P (2005) Orexin loss in Huntington’s disease. Hum Mol Genet 14:39–47

    Article  PubMed  CAS  Google Scholar 

  9. Baumann CR, Dauvilliers Y, Mignot E, Bassetti CL (2004) Normal CSF hypocretin-1 (orexin A) levels in dementia with Lewy bodies associated with excessive daytime sleepiness. Eur Neurol 52:73–6

    Article  PubMed  CAS  Google Scholar 

  10. Gerashchenko D, Murillo-Rodriguez E, Lin L, Xu M, Hallett L, Nishino S, Mignot E, Shiromani PJ (2003) Relationship between CSF hypocretin levels and hypocretin neuronal loss. Exp Neurol 184:1010–6

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Christian R. Baumann.

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Received in revised form: 9 January 2006

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Baumann, C.R., Hersberger, M. & Bassetti, C.L. Hypocretin-1 (orexin A) levels are normal in Huntington’s disease. J Neurol 253, 1232–1233 (2006). https://doi.org/10.1007/s00415-006-0146-7

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  • DOI: https://doi.org/10.1007/s00415-006-0146-7

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