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Genetic polymorphism of 15 autosomal short tandem repeats in Baloch population of Pakistan

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Abstract

Allele frequencies and forensic statistical parameters of 15 autosomal short tandem repeats (STRs) were evaluated in 200 genetically unrelated individuals of the Baloch population of Pakistan. Total 155 alleles were observed with allele frequencies ranged from 0.003 to 0.425. Among the 15 STRs, D2S1338 was found to be the most polymorphic and discriminating locus while TPOX was the least polymorphic and discriminating locus. The combined power of discrimination (CPD), combined power of exclusion (CPE), and combined matching probability (CMP) were found to be 0.9999999999999999978, 0.999994252, and 2.14012 × 10−18, respectively. No significant deviation from Hardy–Weinberg Equilibrium (HWE) was observed except for locus D21S11. Additionally, a correlation between previously published data and Baloch population is also presented.

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References

  1. Siddique Q (2014) Pakistani or Baloch? A Precursory Study of the Baloch Separatist Movement in Pakistan. SISA Report No

  2. Blood PR (1996) Pakistan: a country study. DIANE Publishing

  3. Khan A (2003) Baloch ethnic nationalism in Pakistan: from Guerrilla War to nowhere? Asian ethnicity 4(2):281–293

    Article  Google Scholar 

  4. Wolpert SA (1977) A new history of India. Oxford University Press, New York

    Google Scholar 

  5. Quddus SA (1990) The Tribal Baluchistan. Ferozsons

  6. Marri MKB (1997) Searchlights on Baloches and Balochistan. Ferozsons

  7. Tereba A (1999) Tools for analysis of population statistics. Profiles in DNA. (2):14–16

  8. Liu K, Muse SV (2005) PowerMarker: an integrated analysis environment for genetic marker analysis. Bioinformatics 21(9):2128–2129

    Article  CAS  Google Scholar 

  9. Excoffier L, Lischer HE (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10(3):564–567

    Article  Google Scholar 

  10. Parson W, Roewer L (2010) Publication of population data of linearly inherited DNA markers in the International Journal of Legal Medicine. Int J Legal Med 124(5):505–509

    Article  Google Scholar 

  11. Poetsch M, Bajanowski T, Pfeiffer H (2012) The publication of population genetic data in the International Journal of Legal Medicine: guidelines. Int J Legal Med 126:489–490

    Article  Google Scholar 

Download references

Acknowledgements

We thank all the participants in this study. Also, I would like to thank Ms. Dur-E-Shahwar for her help and cooperation.

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Authors and Affiliations

  1. Forensic Services Laboratory, Centre for Applied Molecular Biology, University of the Punjab, Lahore, Pakistan

    Aleena Ahmad Khan, Rukhsana Perveen, Nadeem Sheikh, Zunaira Batool, Muhammad Shahzad & Sana Kaleem

  2. Centre for Advanced Studies in Vaccinology and Biotechnology, University of Balochistan, Quetta, Pakistan

    Babar Hilal Ahmad Abbasi

Authors
  1. Aleena Ahmad Khan
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  2. Rukhsana Perveen
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  3. Nadeem Sheikh
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  4. Babar Hilal Ahmad Abbasi
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  5. Zunaira Batool
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  6. Muhammad Shahzad
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  7. Sana Kaleem
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Correspondence to Aleena Ahmad Khan.

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Khan, A.A., Perveen, R., Sheikh, N. et al. Genetic polymorphism of 15 autosomal short tandem repeats in Baloch population of Pakistan. Int J Legal Med 133, 775–776 (2019). https://doi.org/10.1007/s00414-018-1878-5

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  • DOI: https://doi.org/10.1007/s00414-018-1878-5

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