Abstract
The genetic polymorphisms of 23 autosomal short tandem repeat (STR) loci included in the HuaxiaTM Platinum kit were evaluated in 1533 unrelated healthy Guangdong Han individuals living in the Guangdong Province in southern China. All of the loci reached the Hardy–Weinberg equilibrium. These loci were examined to determine the allele frequencies and forensic statistical parameters. The genetic relationship between the Guangdong Han and other Chinese populations was also estimated. The combined discrimination power and the probability of excluding the paternity of 23 STR loci were 0.999 999 999 999 999 999 999 999 999 74 and 0.999 999 999 72, respectively. These results suggested that the 23 STR loci are highly polymorphic and suitable for personal forensic identification and paternity testing.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Walsh PS, Metzger DA, Higuchi R (1991) Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. BioTechniques 10:506–513
Lincoln PJ (1997) DNA recommendations—further report of the DNA Commission of the ISFH regarding the use of short tandem repeat systems. Forensic Sci Int 87:181–184
Bar W, Brinkmann B, Budowle B, Carracedo A, Gill P, Lincoln P, Mayr W, Olaisen B (1997) DNA recommendations. Further report of the DNA Commission of the ISFH regarding the use of short tandem repeat systems. International Society for Forensic Haemogenetics. Int J Legal Med 110:175–176
Zhao F, Wu XY, Cai GQ, Xu CC (2003) The application of Modified-Powerstates software in forensic biostatistics (in Chinese). Chin J Forensic Med 18:297–298
Excoffier L, Lischer HE (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10:564–567
Retief JD (2000) Phylogenetic analysis using PHYLIP. Methods Mol Biol 132:243–258
Tamura K, Stecher G, Peterson D, Filipski A, Kumar S (2013) MEGA6: molecular evolutionary genetics analysis version 6.0. Mol Biol Evol 30:2725–2729
Chen L, Lu H, Qiu P, Yang X, Liu C (2015) Polymorphism analysis of 15 STR loci in a large sample of Guangdong (southern China) Han population. Leg Med (Tokyo) 17:489–492
Lu H, Qiu P, Liu C, Du W, Chen L (2016) Genetic polymorphism of 21 non-CODIS STR loci for Guangdong (southern China) Han population. Forensic Sci Int Genet
Poetsch M, Bajanowski T, Pfeiffer H (2012) The publication of population genetic data in the International Journal of Legal Medicine: guidelines. Int J Legal Med 126:489–490
Acknowledgments
We would like to thank the donors who contributed samples for this study. This work was supported by the grants from the Natural Science Foundation of China (31660310), the Science and Technology Planning Projects of Yunnan Province (2013FZ066, 2014FZ005), and the Yunnan Educational Science Foundation program (2014Y180).
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Conflict of interest
The authors declare that they have no conflicts of interest.
Rights and permissions
About this article
Cite this article
Yang, L., Zhang, X., Zhao, L. et al. Population data of 23 autosomal STR loci in the Chinese Han population from Guangdong Province in southern China. Int J Legal Med 132, 133–135 (2018). https://doi.org/10.1007/s00414-017-1588-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00414-017-1588-4