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Expression of heat-shock protein 70 (Hsp70) in the respiratory tract and lungs of fire victims

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Abstract

Immunohistochemical investigation of the respiratory tract and lungs of 63 fire victims revealed a statistically significant enhanced expression of heat-shock protein 70 (Hsp70) in the epiglottis, the trachea, and the main and the peripheral bronchi compared with a control group. In the fire victims, a strong expression of Hsp70 was discernible not only particularly in the vessels but also in seromucous secretory cells, ciliated epithelial cells, smooth muscle cells, and alveolar cells. The results suggest a vital or supravital reaction due to the inhalation of hot fire fumes.

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Authors and Affiliations

  1. Institute of Legal Medicine, Albert Ludwig University, Albertstraße 9, 79104, Freiburg, Germany

    S. Marschall & M. Bohnert

  2. Institute of Legal Medicine, University of Cologne, Melatengürtel 60-62, 50823, Cologne, Germany

    M. A. Rothschild

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  1. S. Marschall
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  2. M. A. Rothschild
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  3. M. Bohnert
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Correspondence to M. Bohnert.

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Marschall, S., Rothschild, M.A. & Bohnert, M. Expression of heat-shock protein 70 (Hsp70) in the respiratory tract and lungs of fire victims. Int J Legal Med 120, 355–359 (2006). https://doi.org/10.1007/s00414-006-0105-y

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  • DOI: https://doi.org/10.1007/s00414-006-0105-y

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