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The role of SUMO in chromosome segregation

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Abstract

Chromosome segregation is an essential feature of the eukaryotic cell cycle. Efficient chromosome segregation requires the co-ordination of several cellular processes; some of which involve gross rearrangements of the overall structure of the genetic material. Recent advances in the analysis of the role of SUMO (small ubiquitin-like modifier) and in the identification of SUMO-modified targets indicate that sumoylation is likely to have several key roles in regulating chromosome segregation This mini-review summarises the recently published data concerning the role of SUMO in the processes required for efficient chromosome segregation.

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Acknowledgement

FZW thanks the Leverhulme Trust for a research fellowship (RFG/10839).

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Authors and Affiliations

  1. Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton, E Sussex, BN1 9QG, UK

    Felicity Z. Watts

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  1. Felicity Z. Watts
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Correspondence to Felicity Z. Watts.

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Communicated by E.A. Nigg

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Watts, F.Z. The role of SUMO in chromosome segregation. Chromosoma 116, 15–20 (2007). https://doi.org/10.1007/s00412-006-0079-z

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  • DOI: https://doi.org/10.1007/s00412-006-0079-z

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