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Cardiovascular effects after low-dose exposure and radiotherapy: what research is needed?

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Abstract

The authors of this report met at the Head Quarter of the International Atomic Energy Agency (IAEA) in Vienna, Austria, on 2–4 July 2012, for intensive discussions of an abundance of original publications on new epidemiological studies on cardiovascular effects after low-dose exposure and radiotherapy and radiobiological experiments as well as several comprehensive reviews that were published since the previous meeting by experts sponsored by the IAEA in June 2006. The data necessitated a re-evaluation of the situation with special emphasis on the consequences current experimental and clinical data may have for clinical oncology/radiotherapy and radiobiological research. The authors jointly arrived at the conclusions and recommendations presented here.

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  1. Jan Wondergem

    Present address: Department of Radiology, Leiden University Medical Centre, Albinusdreef 2, PO Box 9600, 2300 RC, Leiden, The Netherlands

Authors and Affiliations

  1. Applied Radiation Biology and Radiotherapy Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Wagrammer Strasse 5, PO box 100, 1400, Vienna, Austria

    Jan Wondergem

  2. Division of Radiation Health, Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Biomedical Research Building 2, room 410-2, 4301 West Markham, Slot 522-10, Little Rock, AR, 72205, USA

    Marjan Boerma

  3. Radiation Effects Research Foundation, 5-2 Hijiyama-park, Minami-ku, Hiroshima, 732-0815, Japan

    Kazunori Kodama

  4. Biological Stress Response (H3), Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands

    Fiona A. Stewart

  5. Osterberg 4, 83703, Gmund, Germany

    Klaus R. Trott

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  1. Jan Wondergem
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Correspondence to Jan Wondergem.

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Wondergem, J., Boerma, M., Kodama, K. et al. Cardiovascular effects after low-dose exposure and radiotherapy: what research is needed?. Radiat Environ Biophys 52, 425–434 (2013). https://doi.org/10.1007/s00411-013-0489-2

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