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Intragastric Balloon for the Treatment of Obesity: Evaluation of Pulmonary Function Over a 3-Month Period

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Abstract

Background

Obesity has become a global epidemic in the 21st century, and the placement of an intragastric balloon (IB) is a therapeutic modality used to treat it. Our objectives for this study were to evaluate changes in lung function resulting from IB use and to correlate the pattern of body fat distribution with changes in lung function.

Methods

This was an interventional study with 30 overweight and obese patients with metabolic syndrome. All of the subjects underwent anthropometric measurements, assessment of their body fat distribution pattern by dual-energy X-ray absorptiometry, and pulmonary function testing before implantation of the IB.

Results

During the initial evaluations, the main pulmonary function abnormalities observed were decreased expiratory reserve volume (ERV), decreased total lung capacity (TLC), and increased diffusing capacity of carbon monoxide (DLCO), which occurred in 56.7, 40, and 23.3 % of patients, respectively. We observed a statistically significant positive correlation between the DLCO and the percentage of trunk fat mass (ρ = 0.42; p < 0.01). Three months after placement of the IB, there was a significant reduction in the body mass index (p < 0.0001) and the maximal inspiratory pressure (p < 0.009). We also observed a significant increase in the forced vital capacity (p < 0.0001), TLC (p < 0.001), and ERV (p < 0.0001).

Conclusions

Weight loss as a result of IB causes increased static lung volumes and decreased inspiratory muscle strength. Additionally, being overweight and obese is related to increased DLCO, especially in individuals with truncal obesity.

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Authors and Affiliations

  1. Postgraduate Program in Medical Sciences, State University of Rio de Janeiro, Rua Araguaia, 1266, bloco 1/405, Freguesia, Jacarepaguá, Rio de Janeiro, RJ, 22745-271, Brazil

    Thiago Thomaz Mafort & Agnaldo José Lopes

  2. Postgraduate Program in Endocrinology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

    Eduardo Madeira, Miguel Madeira & Maria Lucia Fleiuss Farias

  3. Endocrinology Department, State Institute of Diabetes and Endocrinology, Rio de Janeiro, Brazil

    Erika Paniago Guedes & Rodrigo Oliveira Moreira

  4. Department of Rheumatology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

    Laura Maria Carvalho de Mendonça

Authors
  1. Thiago Thomaz Mafort
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  2. Eduardo Madeira
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  3. Miguel Madeira
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  4. Erika Paniago Guedes
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  5. Rodrigo Oliveira Moreira
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  6. Laura Maria Carvalho de Mendonça
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  7. Maria Lucia Fleiuss Farias
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  8. Agnaldo José Lopes
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Correspondence to Agnaldo José Lopes.

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Mafort, T.T., Madeira, E., Madeira, M. et al. Intragastric Balloon for the Treatment of Obesity: Evaluation of Pulmonary Function Over a 3-Month Period. Lung 190, 671–676 (2012). https://doi.org/10.1007/s00408-012-9415-7

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  • DOI: https://doi.org/10.1007/s00408-012-9415-7

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