Abstract
Little is known about the changes of people with schizophrenia disability in Taiwan who receive routine treatments under the current mental healthcare system. The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) was used to assess and track changes in the degree of disability in people with schizophrenia before and after 4 years of follow-up. Data on 4497 people with schizophrenia were acquired from the Taiwan Data Bank of Persons with Disability. The WHODAS 2.0 was used for disability assessment, and the chi-square test, logistic regression and generalised estimating equations were adopted for statistical analysis. People with schizophrenia exhibited improvement in cognition, mobility and participation among the six domains as well as in the overall score. The degree of disability in all domains remained mild to moderate among people aged 18–64 years; the degree of disability in cognition declined from moderate to severe among patients aged ≥65 years. The degree of disability in all domains remained mild to moderate among people with mild to moderate impairment; among those with severe impairment, the degree of disability in the domains of cognition and life activities declined from moderate to severe and the degree of disability in the domain of mobility declined from mild to moderate. Community-dwelling patients exhibited less degree of disability in all domains than their institutionalised peers. Early detection and treatment and an emphasis on communication and social problem-solving skills in rehabilitation programmes are recommended for people with schizophrenia.
Similar content being viewed by others
References
Świtaj P, Anczewska M, Chrostek A, Sabariego C, Cieza A, Bickenbach J, Chatterji S (2012) Disability and schizophrenia: a systematic review of experienced psychosocial difficulties. BMC Psychiatry 12(1):1–12. https://doi.org/10.1186/1471-244x-12-193
Guilera G, Gomez-Benito J, Pino O, Rojo JE, Cuesta MJ, Martinez-Aran A, Safont G, Tabares-Seisdedos R, Vieta E, Bernardo M, Crespo-Facorro B, Franco M, Rejas J (2012) Utility of the World Health Organization disability assessment schedule II in schizophrenia. Schizophr Res 138(2–3):240–247. https://doi.org/10.1016/j.schres.2012.03.031
Shioda A, Tadaka E, Okochi A (2016) Loneliness and related factors among people with schizophrenia in Japan: a cross-sectional study. J Psychiatr Ment Health Nurs 23(6–7):399–408
Mausbach BT, Depp CA, Cardenas V, Jeste DV, Patterson TL (2008) Relationship between functional capacity and community responsibility in patients with schizophrenia: differences between independent and assisted living settings. Community Ment Health J 44(5):385–391
Johnson S, Sathyaseelan M, Charles H, Jacob KS (2014) Predictors of disability: a 5-year cohort study of first-episode schizophrenia. Asian J Psychiatr 9:45–50. https://doi.org/10.1016/j.ajp.2014.01.003
Wiersma D, Wanderling J, Dragomirecka E, Ganev K, Harrison G, Der Heiden WA, Nienhuis F, Walsh D (2000) Social disability in schizophrenia: its development and prediction over 15 years in incidence cohorts in six European centres. Psychol Med 30(5):1155–1167
World Health Organization (2016) Schizophrenia. http://www.who.int/mediacentre/factsheets/fs397/en/. Accessed 6 Mar 2017
Chiang C-L, Chen P-C, Huang L-Y, Kuo P-H, Tung Y-C, Liu C-C, Chen WJ (2017) Time trends in first admission rates for schizophrenia and other psychotic disorders in Taiwan, 1998–2007: a 10-year population-based cohort study. Soc Psychiatry Psychiatr Epidemiol 52(2):163–173
Nemoto T, Niimura H, Ryu Y, Sakuma K, Mizuno M (2014) Long-term course of cognitive function in chronically hospitalized patients with schizophrenia transitioning to community-based living. Schizophr Res 155(1):90–95
Kunitoh N (2013) From hospital to the community: the influence of deinstitutionalization on discharged long-stay psychiatric patients. Psychiatry Clin Neurosci 67(6):384–396
Spaulding WD, Sullivan ME (2016) Treatment of cognition in the schizophrenia spectrum: the context of psychiatric rehabilitation. Schizophr Bull 42(Suppl 1):S53–S61. https://doi.org/10.1093/schbul/sbv163
Mizuno E, Iwasaki M, Sakai I, Kamizawa N (2015) Experiences of community-dwelling persons recovering from severe mental illness. Arch Psychiatr Nurs 29(2):127–131
Hobbs C, Newton L, Tennant C, Rosen A, Tribe K (2002) Deinstitutionalization for long-term mental illness: a 6-year evaluation. Aust N Z J Psychiatry 36(1):60–66
Carmona VR, Gómez-Benito J, Huedo-Medina TB, Rojo JE (2017) Employment outcomes for people with schizophrenia spectrum disorder: a meta-analysis of randomized controlled trials. Int J Occup Med Environ Health 30(3):345
Luciano A, Metcalfe JD, Bond GR, Xie H, Miller AL, Riley J, O’Malley AJ, Drake RE (2016) Hospitalization risk before and after employment among adults with schizophrenia, bipolar disorder, or major depression. Psychiatr Serv 67(10):1131–1138
McGrath LM, Cornelis MC, Lee PH, Robinson EB, Duncan LE, Barnett JH, Huang J, Gerber G, Sklar P, Sullivan P (2013) Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia. Am J Med Genet Part B Neuropsychiatr Genet 162(8):779–788
Üstün TB, Chatterji S, Kostanjsek N, Rehm J, Kennedy C, Epping-Jordan J, Saxena S, Korff MV, Pull C (2010) Developing the World Health Organization disability assessment schedule 2.0. Bull World Health Organ 88(11):815–823
Gold LH (2014) DSM-5 and the assessment of functioning: the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). J Am Acad Psychiatry Law 42(2):173–181
Gspandl S, Peirson RP, Nahhas RW, Skale TG, Lehrer DS (2018) Comparing global assessment of functioning (GAF) and World Health Organization disability assessment schedule (WHODAS) 2.0 in schizophrenia. Psychiatry Res 259:251–253
Chen R, Liou T-H, Chang K-H, Yen C-F, Liao H-F, Chi W-C, Chou K-R (2017) Assessment of functioning and disability in patients with schizophrenia using the WHO disability assessment schedule 2.0 in a large-scale database. Eur Arch Psychiatry Clin Neurosci 268(1):65–75
Adegbaju DA, Olagunju AT, Uwakwe R (2013) A comparative analysis of disability in individuals with bipolar afective disorder and schizophrenia in a sub-Saharan African mental health hospital: towards evidence-guided rehabilitation intervention. Soc Psychiatry Psychiatr Epidemiol 48(9):1405–1415
Yen C-F, Hwang A-W, Liou T-H, Chiu T-Y, Hsu H-Y, Chi W-C, Wu T-F, Chang B-S, Lu S-J, Liao H-F (2014) Validity and reliability of the functioning disability evaluation scale-adult version based on the WHODAS 2.0–36 items. J Formos Med Assoc 113(11):839–849
Chiu T-Y, Yen C-F, Chou C-H, Lin J-D, Hwang A-W, Liao H-F, Chi W-C (2014) Development of traditional Chinese version of World Health Organization disability assessment schedule 2.0 36– item (WHODAS 2.0) in Taiwan: validity and reliability analyses. Res Dev Disabil 35(11):2812–2820
Trieman N, Wills W, Lef J (1996) TAPS Project 28: does reprovision beneit elderly long-stay mental patients? Schizophr Res 21(3):199–208
Hobbs C, Tennant C, Rosen A, Newton L, Lapsley HM, Tribe K, Brown JE (2000) Deinstitutionalisation for long-term mental illness: a 2-year clinical evaluation. Aust N Z J Psychiatry 34(3):476–483
Borge L, Martinsen EW, Ruud T, Watne Ø, Friis S (1999) Quality of life, loneliness, and social contact among long-term psychiatric patients. Psychiatr Serv 50(1):81–84
Horan ME, Muller JJ, Winocur S, Barling N (2001) Quality of life in boarding houses and hostels: a residents’ perspective. Community Ment Health J 37(4):323–334
Harvey PD, Heaton RK, Carpenter WT, Green MF, Gold JM, Schoenbaum M (2012) Functional impairment in people with schizophrenia: focus on employability and eligibility for disability compensation. Schizophr Res 140(1):1–8
Rosenheck R, Leslie D, Keefe R, McEvoy J, Swartz M, Perkins D, Stroup S, Hsiao JK, Lieberman J, Group CSI (2006) Barriers to employment for people with schizophrenia. Am J Psychiatry 163(3):411–417
Salkever DS, Karakus MC, Slade EP, Harding CM, Hough RL, Rosenheck RA, Swartz MS, Barrio C, Yamada AM (2007) Measures and predictors of community-based employment and earnings of persons with schizophrenia in a multisite study. Psychiatr Serv 58(3):315–324
Marwaha S, Johnson S, Bebbington P, Staford M, Angermeyer MC, Brugha T, Azorin J-M, Kilian R, Hansen K, Toumi M (2007) Rates and correlates of employment in people with schizophrenia in the UK, France and Germany. Br J Psychiatry 191(1):30–37
Killackey E (2008) Something for everyone: employment interventions in psychotic illness. Acta Neuropsychiatr 20(5):277–279
Ministry of the Interior ROCT (2016) Disabled Welfare, pp 1–35
Jørgensen P (1987) Social course and outcome of delusional psychosis. Acta Psychiatr Scand 75(6):629–634
Arns PG, Linney JA (1993) Work, self, and life satisfaction for persons with severe and persistent mental disorders. Psychosocial Rehabil J 17(2):63
Brekke JS, Levin S, Wolkon GH, SobeI E, Slade E (1993) Psychosocial functioning and subjective experience in schizophrenia. Schizophr Bull 19(3):599
Dongen CJV (1998) Self-esteem among persons with severe mental illness. Issues Ment Health Nurs 19(1):29–40
Yamaguchi S, Mino Y, Uddin S (2011) Strategies and future attempts to reduce stigmatization and increase awareness of mental health problems among young people: a narrative review of educational interventions. Psychiatry Clin Neurosci 65(5):405–415
Haro J, Novick D, Suarez D, Ochoa S, Roca M (2008) Predictors of the course of illness in outpatients with schizophrenia: a prospective three year study. Prog Neuropsychopharmacol Biol Psychiatry 32(5):1287–1292
Provencher HL, Gregg R, Mead S, Mueser KT (2002) The role of work in the recovery of persons with psychiatric disabilities. Psychiatr Rehabil J 26(2):132
Marzanski M, Jainer AK, Stallard N (2008) Naturalistic study of the efficacy of different treatment strategies in relapse prevention in bipolar affective disorders. Int Med J 15(4):277–285
Schennach R, Obermeier M, Meyer S, Jäger M, Schmauss M, Laux G, Pfeifer H, Naber D, Schmidt LG, Gaebel W (2012) Predictors of relapse in the year after hospital discharge among patients with schizophrenia. Psychiatr Serv 63(1):87–90
Adamczyk P, Daren A, Sułecka A, Błądziński P, Cichocki Ł, Kalisz A, Gawęda Ł, Cechnicki A (2016) Do better communication skills promote sheltered employment in schizophrenia? Schizophr Res 176(2):331–339
Lexén A, Bejerholm U (2016) Exploring communication and interaction skills at work among participants in individual placement and support. Scand J Occup Ther 23(4):314–319
Dickinson D, Bellack AS, Gold JM (2006) Social/communication skills, cognition, and vocational functioning in schizophrenia. Schizophr Bull 33(5):1213–1220
Tsang H, Bell M, Cheung V, Tam K, Yeung W (2016) Integrated supported employment plus cognitive remediation training for people with schizophrenia. Hong Kong Med J 22(1):15–18
Lee RSC, Hermens DF, Naismith SL, Lagopoulos J, Jones A, Scott J, Chitty KM, White D, Robillard R, Scott EM, Hickie IB (2015) Neuropsychological and functional outcomes in recent-onset major depression, bipolar disorder and schizophrenia-spectrum disorders: a longitudinal cohort study. Transl Psychiatry 5(4):e555. https://doi.org/10.1038/tp.2015.50
Nordstroem A-L, Talbot D, Bernasconi C, Berardo CG, Lalonde J (2017) Burden of illness of people with persistent symptoms of schizophrenia: a multinational cross-sectional study. Int J Soc Psychiatry 63(2):139–150
Harvey PD (2013) Cognitive aspects of schizophrenia. Wiley Interdiscip Rev Cogn Sci 4(6):599–608
Acknowledgements
We thank Hui-Han Lin for the assistance in data analysis in this study.
Funding
This study was supported by the Ministry of Health and Welfare, Taiwan (Grant Nos. M03F4037, M04F4027, M05F5044, M06F4035 and M07F5193).
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Conflict of interest
The authors declare that they have no competing interests.
Ethical approval
Joint Institutional Review Board of Taipei Medical University (N201805048).
Rights and permissions
About this article
Cite this article
Chen, R., Liou, TH., Miao, NF. et al. Using World Health Organization Disability Assessment Schedule 2.0 in people with schizophrenia: a 4-year follow-up. Eur Arch Psychiatry Clin Neurosci 270, 301–310 (2020). https://doi.org/10.1007/s00406-019-01000-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00406-019-01000-5