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Efficacy and safety of LigaSure™ small jaw instrument in thyroidectomy: a 1-year prospective observational study

  • Head and Neck
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European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

To compare the efficacy and safety profiles of LigaSure™ small jaw instrument (LSJI) versus conventional technique in patients undergoing open thyroidectomy.

Methods

This single-center, prospective, observational study conducted in Zhejiang Provincial Cancer Hospital enrolled patients who underwent thyroidectomy between September 2013 and September 2014. The primary study outcomes included determination of blood loss, operative duration, length of hospital stay, and drainage volume. The secondary outcomes included evaluation of recurrent laryngeal nerve palsy, postoperative bleeding, and hypoparathyroidism.

Results

A total of 842 patients undergoing thyroidectomy either with conventional method (n = 440) or with LSJI (n = 402) were enrolled. A significantly reduced operative time and intraoperative blood loss were noted in the LSJI group (p < .001) compared with the conventional group. Further, the LSJI group also demonstrated a significantly lower postoperative drainage (p < .05) compared with the conventional group. Length of hospital stay and incidence of postoperative complications were similar in both the LSJI and conventional groups.

Conclusion

LigaSure hemostasis in thyroidectomy appears to result in significantly reduced operative time, intraoperative blood loss, and postoperative drainage compared with the conventional method in Chinese patients.

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References

  1. Sosa JA, Bowman HM, Tielsch JM et al (1998) The importance of surgeon experience for clinical and economic outcomes from thyroidectomy. Ann Surg 228:320–330

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Zare M, Ayatollahi S, Kargar S (2016) Comparison of short-term postoperative complications of thyroidectomy using ligature and suture ligation. Adv Biomed Res 5:37. https://doi.org/10.4103/2277-9175.178782

    Article  PubMed  PubMed Central  Google Scholar 

  3. Bircan HY, Inal A, Ozcelik U et al (2014) LigaSure® versus clamp tie technique for thyroid surgery; decreased operative time versus increased inflammatory effect: a prospective randomized study. Eur Rev Med Pharmacol Sci 18:1997–2005

    CAS  PubMed  Google Scholar 

  4. Youssef T, Mahdy T, Farid M, Latif AA (2008) Thyroid surgery: use of the LigaSure Vessel Sealing System versus conventional knot tying. Int J Surg Lond Engl 6:323–327. https://doi.org/10.1016/j.ijsu.2008.05.005

    Article  Google Scholar 

  5. Molnar C, Voidazan S, Rad CC et al (2014) Total thyroidectomy with LigaSure Small Jaw versus conventional thyroidectomy—a clinical study. Chir Buchar Rom 1990 109:608–612

    CAS  Google Scholar 

  6. Smith CT, Zarebczan B, Alhefdhi A, Chen H (2011) Infrared thermographic profiles of vessel sealing devices on thyroid parenchyma. J Surg Res 170:64–68. https://doi.org/10.1016/j.jss.2011.03.005

    Article  PubMed  PubMed Central  Google Scholar 

  7. Khafagy A, Abdelnaby I (2013) Total thyroidectomy: Ligasure versus Clamp and Knot technique for intraoperative hemostasis. Egypt J Ear Nose Throat Allied Sci 14:59–65. https://doi.org/10.1016/j.ejenta.2013.02.001

    Article  Google Scholar 

  8. Ruggiero R, Gubitosi A, Conzo G et al (2014) Sutureless thyroidectomy. Int J Surg Lond Engl 12(Suppl 1):S189–193. https://doi.org/10.1016/j.ijsu.2014.05.011

    Article  Google Scholar 

  9. LigasureTM Small Jaw Open Instrument Product Info Sheet. Medtronic Official Web site http://www.medtronic.com/content/dam/covidien/library/global/english/product/vessel-sealing/ligasure-small-jaw/ligasure-small-jaw-info-sheet.pdf. Accessed 23 Oct 2017

  10. LigasureTM Small Jaw Open Instrument Overview. Medtronic Official Web site. http://www.medtronic.com/covidien/products/vessel-sealing/ligasure-small-jaw. Accessed 23 Oct 2017

  11. Hirunwiwatkul P, Tungkavivachagul S (2013) A multicenter, randomized, controlled clinical trial of LigaSure small jaw vessel sealing system versus conventional technique in thyroidectomy. Eur Arch Oto-Rhino-Laryngol 270:2109–2114. https://doi.org/10.1007/s00405-012-2289-8

    Article  Google Scholar 

  12. Coiro S, Frattaroli FM, De Lucia F et al (2015) A comparison of the outcome using Ligasure™ small jaw and clamp-and-tie technique in thyroidectomy: a randomized single center study. Langenbecks Arch Surg 400:247–252. https://doi.org/10.1007/s00423-014-1270-y

    Article  CAS  PubMed  Google Scholar 

  13. Peker K, Inal A, Güllü H et al (2013) Comparison of vessel sealing systems with conventional. Iran Red Crescent Med J 15:488–496. https://doi.org/10.5812/ircmj.10180

    Article  PubMed  PubMed Central  Google Scholar 

  14. Sayir F, Cobanoğlu U, Sehitoğulları A (2012) The use of LigaSure Vessel Sealing System in Ivor Lewis esophagectomy. J Cardiothorac Surg 7:10. https://doi.org/10.1186/1749-8090-7-10

    Article  PubMed  PubMed Central  Google Scholar 

  15. Yang J, Cui P-J, Han H-Z, Tong D-N (2013) Meta-analysis of stapled hemorrhoidopexy vs LigaSure hemorrhoidectomy. World J Gastroenterol 19:4799–4807. https://doi.org/10.3748/wjg.v19.i29.4799

    Article  PubMed  PubMed Central  Google Scholar 

  16. Hu J, Zhao N, Kong R et al (2016) Total thyroidectomy as primary surgical management for thyroid disease: surgical therapy experience from 5559 thyroidectomies in a less-developed region. World J Surg Oncol 14:20. https://doi.org/10.1186/s12957-016-0772-1

    Article  PubMed  PubMed Central  Google Scholar 

  17. Liu X-Y, Zhu L-J, Cui D et al (2014) Annual financial impact of thyroidectomies for nodular thyroid disease in China. Asian Pac J Cancer Prev APJCP 15:5921–5926

    Article  PubMed  Google Scholar 

  18. Marrazzo A, Casà L, David M et al (2007) Thyroidectomy with LigaSure versus traditional thyroidectomy: our experience. Chir Ital 59:361–365

    PubMed  Google Scholar 

  19. Saint Marc O, Cogliandolo A, Piquard A et al (2007) LigaSure vs clamp-and-tie technique to achieve hemostasis in total thyroidectomy for benign multinodular goiter: a prospective randomized study. Arch Surg Chic Ill 1960 142:150–156. https://doi.org/10.1001/archsurg.142.2.150 (discussion 157)

    Google Scholar 

  20. Yao HS, Wang Q, Wang WJ, Ruan CP (2009) Prospective clinical trials of thyroidectomy with LigaSure vs conventional vessel ligation: a systematic review and meta-analysis. Arch Surg Chic Ill 1960 144:1167–1174. https://doi.org/10.1001/archsurg.2009.201

    Google Scholar 

  21. Kirdak T, Korun N, Ozguc H (2005) Use of ligasure in thyroidectomy procedures: results of a prospective comparative study. World J Surg 29:771–774. https://doi.org/10.1007/s00268-005-7788-y

    Article  PubMed  Google Scholar 

  22. Schiphorst AHW, Twigt BA, Elias SG, van Dalen T (2012) Randomized clinical trial of LigaSure versus conventional suture ligation in thyroid surgery. Head Neck Oncol 4:2. https://doi.org/10.1186/1758-3284-4-2

    Article  PubMed  PubMed Central  Google Scholar 

  23. Cipolla C, Graceffa G, Sandonato L et al (2008) LigaSure in total thyroidectomy. Surg Today 38:495–498. https://doi.org/10.1007/s00595-007-3665-7

    Article  PubMed  Google Scholar 

  24. Gentile M, De Rosa M, Carbone G et al (2011) LigaSure haemorrhoidectomy versus conventional diathermy for IV-degree haemorrhoids: is it the treatment of choice? A randomized, clinical trial. ISRN Gastroenterol 2011:467258. https://doi.org/10.5402/2011/467258

    Article  PubMed  Google Scholar 

  25. Kuboki A, Nakayama T, Konno W et al (2013) New technique using an energy-based device versus conventional technique in open thyroidectomy. Auris Nasus Larynx 40:558–562. https://doi.org/10.1016/j.anl.2013.04.005

    Article  PubMed  Google Scholar 

  26. Antonio M, Pietra T, Domenico L et al (2007) Does LigaSure reduce fluid drainage in axillary dissection? A randomized prospective clinical trial. Ecancermedicalscience 1:61. https://doi.org/10.3332/eCMS.2007.61

    CAS  PubMed  PubMed Central  Google Scholar 

  27. Singh P, O’Connell D, Langille M et al (2010) LigaSure versus conventional hemostasis in thyroid surgery: prospective randomized controlled trial. J Otolaryngol Head Neck Surg 39:378–384

    PubMed  Google Scholar 

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Acknowledgements

The authors acknowledge Dr. Gui Su (Medtronic) for providing constructive comments to improve the manuscript and for proofreading the manuscript and Dr. Amit Bhat and Karan Sharma (Indegene Pvt. Ltd., Bangalore), for providing manuscript writing support and technical assistance, as sponsored by Medtronic. The authors have no conflicts of interest to disclose.

Funding

None.

Author information

Authors and Affiliations

  1. Department of Head and Neck Surgery, Zhejiang Cancer Hospital, Hangzhou, 310022, China

    Xiao-Chun Mao, Chao Chen & Ke-Jing Wang

Authors
  1. Xiao-Chun Mao
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  2. Chao Chen
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  3. Ke-Jing Wang
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Contributions

X-CM, CC, and K-JW contributed in conceptualizing the study design, data collection, analysis, and interpretation. All authors were involved in interpretation of results, manuscript writing, and approval of the final draft.

Corresponding author

Correspondence to Ke-Jing Wang.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethics approval

This study was approved by the institutional review board of the Zhejiang Cancer Hospital.

Informed consent

The study was conducted in accordance with the principles of Goof Clinical Practices and Declaration of Helsinki (1964 and its revisions). Patients who provided written informed consent, were enrolled in the study.

Data sharing statement

No additional data available.

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Cite this article

Mao, XC., Chen, C. & Wang, KJ. Efficacy and safety of LigaSure™ small jaw instrument in thyroidectomy: a 1-year prospective observational study. Eur Arch Otorhinolaryngol 275, 1257–1263 (2018). https://doi.org/10.1007/s00405-018-4912-9

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  • DOI: https://doi.org/10.1007/s00405-018-4912-9

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