Skip to main content
Log in

Utility of an intraoperative ultrasound in lateral approach mini-parathyroidectomy with discordant pre-operative imaging

  • Head and Neck
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Objectives of this study were to assess the utility of intra-operative ultrasound to resolve discordant pre-operative imaging prior to a lateral approach mini-parathyroidectomy, by studying prospective case series in a head and neck endocrine unit. Patients with primary hyperparathyroidism due to a single adenoma with discordant pre-operative ultrasound and sestamibi were enrolled. They underwent a further intra-operative ultrasound by a head and neck radiologist with a view to proceed with a mini-parathyroidectomy. The main outcome measure was utility of intra-operative ultrasound compared to operative findings and pre-operative imaging. Secondary measures were complications of mini-parathyroidectomy, operative and ambulatory discharge time. Twenty-two patients underwent surgery with intra-operative ultrasound in the surgical position. The intra-operative ultrasound findings correlated with the operative findings in all cases (100 %). There were 16 inferior adenomas and 6 superior adenomas. Six inferior adenomas were in a retrosternal position, eight were obscured by benign thyroid lesions and a further two reported pre-operatively as superior. Three out of six superior adenomas were reported as inferior pre-operatively as the inferior thyroid artery was inadequately visualised, two were retro-carotid and one was retro-oesophageal. All patients were discharged within 23 h of surgery. There were no unsuccessful focused explorations. Histological analysis confirmed the adenomas. No morbidity (vocal cord palsy, haematoma, hungry bones) was noted. The results indicated that intra-operative ultrasound by a dedicated radiologist is a valuable tool in resolving discordance of pre-operative imaging. Appropriate patient positioning with neck extension and muscle relaxation allows placement of the probe in the obscure retro-carotid and retro-oesophageal locations and unmasks apparent “mediastinal” parathyroids facilitating focused dissection.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Jabiev AA, Lew JI, Solorzano CC (2009) Surgeon-performed ultrasound: a single institution experience in parathyroid localization. Surgery 146:569–575

    Article  PubMed  Google Scholar 

  2. Mihai R, Simon D, Hellman P (2009) Imaging for primary hyperparathyroidism: an evidence-based analysis. Langenbecks Arch Surg 394:765–784

    Article  PubMed  Google Scholar 

  3. Aspinall SR, Nicholson S, Bliss RD, Lennard TWJ (2012) The impact of surgeon-based ultrasonography for parathyroid disease on a British endocrine surgical practice. Ann R Coll Surg Engl 94:17–22

    Article  PubMed  CAS  Google Scholar 

  4. Rubello D, Gross MD, Mariani G, AL-Nahhas A (2007) Scintigraphic techniques in primary hyperparathyroidism: from pre-operative localisation to intra-operative imaging. Eur J Nucl Med Mol Imaging 34:926–933

    Article  PubMed  Google Scholar 

  5. Sackett WR, Barraclough B, Reeve TS, Deldridge LW (2002) Worldwide trends in the surgical treatment of primary hyperparathyroidism in the era of minimally invasive parathyroidectomy. Arch Surg 137:1055–1059

    Article  PubMed  Google Scholar 

  6. Udelsman R, Lin Z, Donovan P (2011) The superiority of minimally invasive parathyroidectomy based on 1650 consecutive patients with primary hyperparathyroidism. Ann Surg 253:585–591

    Article  PubMed  Google Scholar 

  7. Lloyd MNH, Lees WR, Milroy EJG (1990) Pre-operative localisation in primary hyperparathyroidism. Clin Rad 41:239–243

    Article  CAS  Google Scholar 

  8. Beus KS, Stack BC (2004) Synchronous thyroid pathology in patients presenting with primary hyperparathyroidism. Am J Otolaryngol 25:308–312

    Article  PubMed  Google Scholar 

  9. Prasannan S, Davies G, Bochner M, Kollias J, Malycha P (2007) Minimally invasive parathyroidectomy using surgeon-performed ultrasound and sestamibi. ANZ J Surg 77:774–777

    Article  PubMed  Google Scholar 

  10. Solorzano CC, Carneiro-Pla DM, Irvin GL (2006) Surgeon-performed ultrasonography as the initial and only localizing study in sporadic primary hyperparathyroidism. J Am Coll Surg 202:18–24

    Article  PubMed  Google Scholar 

  11. Yeh MW, Barraclough BM, Sidhu SB, Sywak MS, Barraclough BH, Deldridge LW (2006) Two hundred consecutive parathyroid ultrasound studies by a single clinician: The impact of experience. Endoc Prac 12:257–263

    Google Scholar 

  12. Kairys JC, Daskalakis C, Weigel RJ (2006) Surgeon-performed ultrasound for preoperative localization of abnormal parathyroid glands in patients with primary hyperparathyroidism. World J Surg 30:1658–1663

    Article  PubMed  Google Scholar 

  13. Steward DL, Danielson GP, Afman CE, Welge JA (2006) Parathyroid adenoma localization: surgeon-performed ultrasound versus sestamibi. Laryngoscope 116:1380–1384

    Article  PubMed  Google Scholar 

  14. Arora S, Balash PR, Yoo J, Smith GS, Prinz RA (2009) Benefits of surgeon-performed ultrasound for primary hyperparathyroidism. Langenbecks Arch Surg 394:861–867

    Article  PubMed  Google Scholar 

  15. Deutmeyer C, Weingarten M, Doyle M, Carneiro-Pla D (2011) Case series of targeted parathyroidectomy with surgeon-performed ultrasonography as the only preoperative imaging study. J Surg 150:1153–1160

    Article  Google Scholar 

  16. Gurney TA, Orloff LA (2008) Otolaryngologist-head and neck surgeon-performed ultrasonography for parathyroid adenoma localization. Laryngoscope 118:243–246

    Article  PubMed  Google Scholar 

  17. Khalid AN, Hollenbeak CS, Higginbotham BW, Stack BC (2009) Accuracy and definitive interpretation of preoperative technetium 99 m sestamibi imaging based on the discipline of the reader. Head Neck 31:576–582

    Article  PubMed  Google Scholar 

  18. Roy M, Mazeh H, Chen H, Sippel RS (2012) Incidence and localization of ectopic parathyroid adenomas in previously unexplored patients. World J Surg. doi:10.1007/s00268-012-1773-z

    Google Scholar 

  19. Soon PSH, Delbridge LW, Sywak MS, Barraclough BM, Edhouse P, Sidhu SB (2008) Surgeon performed ultrasound facilitates minimally invasive parathyroidectomy by the focused lateral mini-incision approach. World J Surg 32:766–771

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

The authors declare no conflicts of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ali Al-lami.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Al-lami, A., Riffat, F., Alamgir, F. et al. Utility of an intraoperative ultrasound in lateral approach mini-parathyroidectomy with discordant pre-operative imaging. Eur Arch Otorhinolaryngol 270, 1903–1908 (2013). https://doi.org/10.1007/s00405-012-2284-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-012-2284-0

Keywords

Navigation