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Primary intraosseous squamous cell carcinoma of the jaw: two new cases and review of the literature

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Abstract

Background

Primary intraosseous squamous cell carcinoma is very rare. We report two cases of primary intraosseous squamous cell carcinoma of the jaw, one arising from an odontogenic cyst and the other arising de novo.

Methods and results

The first case was a 76-year-old man with right mandible pain. A panoramic radiography and computed tomography revealed a large mandibular radiolucency. A biopsy revealed squamous cell carcinoma, and radiotherapy and hemimandibulectomy were performed. The second case was a 50-year-old man with lymph node swelling on the left neck. Squamous cell carcinoma of the lymph node was suspected after fine needle biopsy. After left neck dissection, histological testing of the odontogenic cyst revealed squamous cell carcinoma, of which the mandible was thought to be the primary site.

Conclusion

Our two cases have no recurrence, and panoramic radiography was a useful tool in the detection of mandible disease.

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References

  1. Pindborg JJ, Kramer IRH, Torloni H (eds) (1972) Histologic typing of odontogenic tumors, jaw cysts and allied lesions. World Health Organization, Geneva, pp 35–36

  2. Waldron CA, Mustoe TA (1989) Primary intraosseous carcinoma of the mandible with probable origin in an odontogenic cyst. Oral Surg Oral Med Oral Pathol 67:716–724

    Article  PubMed  CAS  Google Scholar 

  3. Eversole LR, Siar CH, van der Waal I (2005) Primary intraosseous squamous cell carcinomas. In: Barnes L, Evson JW, Reichart P, Sidransky D (eds) World Health Organization classification of tumors. Pathology and genetics of head and neck tumors. World Health Organization International Agency for Research on Cancer. IACR Press, Lyon, pp 290–291

  4. Huang JW, Luo HY, Li Q, Li TJ (2009) Primary intraosseous squamous cell carcinoma of the jaws. Clinicopathologic presentation and prognostic factors. Arch Pathol Lab Med 133:1834–1840

    PubMed  Google Scholar 

  5. Waltonen JD, Ozer E, Hall NC, Schuller DE, Agrawal A (2009) Metastatic carcinoma of the neck of unknown primary origin: evolution and efficacy of the modern workup. Arch Otolaryngol Head Neck Surg 135:1024–1029

    Article  PubMed  Google Scholar 

  6. Gardner AF (1975) A survey of odontogenic cysts and their relationship to squamous cell carcinoma. Dent J 41:161–167

    PubMed  CAS  Google Scholar 

  7. Sengupta S, Vij H, Vij R (2010) Primary intraosseous carcinoma of the mandible: a report of two cases. J Oral Maxillofac Pathol 14:69–72

    Article  PubMed  Google Scholar 

  8. Bodner L, Manor E, Shear M, van der Waal I (2011) Primary intraosseous squamous cell carcinoma arising in an odontogenic cyst: a clinicopathologic analysis of 116 reported cases. J Oral Pathol Med 40:733–738

    Article  PubMed  Google Scholar 

  9. Thomas G, Pandey M, Mathew A, Abraham EK, Francis A, Somanathan T, Iype M, Sebastian P, Nair MK (2001) Primary intraosseous carcinoma of the jaw: pooled analysis of world literature and report of two new cases. Int J Oral Maxillofac Surg 30:349–355

    Article  PubMed  CAS  Google Scholar 

  10. Lugakingira M, Pytynia K, Kolokythas A, Miloro M (2010) Primary intraosseous carcinoma of the mandible: case report and review of the literature. J Oral Maxillofac Surg 68:2623–2629

    Article  PubMed  Google Scholar 

  11. Dimitrakopoulos I, Psomaderis K, Asimaki A, Papaemanouel S, Karakasis D (2005) Primary de novo intraosseous carcinoma: report of two cases. J Oral Maxillofac Surg 63:1227–1230

    Article  PubMed  Google Scholar 

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Correspondence to Tsutomu Nomura.

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Nomura, T., Monobe, H., Tamaruya, N. et al. Primary intraosseous squamous cell carcinoma of the jaw: two new cases and review of the literature. Eur Arch Otorhinolaryngol 270, 375–379 (2013). https://doi.org/10.1007/s00405-012-2235-9

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  • DOI: https://doi.org/10.1007/s00405-012-2235-9

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