Skip to main content
Log in

SPA therapy of upper respiratory tract inflammations

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

The upper airway respiratory diseases (i.e. common cold, allergic rhinitis, nonallergic/vasomotor rhinitis, acute and chronic rhinosinusitis and nasal polyposis) in which nasal congestion is a common symptom are often undertreated due to the frequent inadequate efficacy and safety concern with current therapies. In scientific literature, few studies seem to support the hypothesis that nasal inhalatory treatment with thermal water promotes the improvement of nasal symptoms, even if the mechanisms by which the improvement from SPA therapy can be expected remain debated. A prospective comparative study with a pre–post design has been performed consecutively enrolling 33 (males 70 %) patients of both genders older than 12 years of age, affected by chronic sinonasal inflammation. All patients underwent a 14-days course of radioactive water warm vapour inhalations followed by nasal aerosol of the same thermal water 10 min each once/day at Merano Therme. At the beginning and end of the study, in all the subjects, nasal function evaluation by active anterior rhinomanometry, mucociliary transport time (MCTt) determination and nasal cytology were performed. After the inhalatory treatment, the mucociliary function was improved and the pathologic mucociliary transport times recorded at the beginning of the study being significantly reduced to physiologic ones. Besides, before treatment, the cytologic picture showed an inflammatory cell infiltration (eosinophils, neutrophils with/without bacteria, mast cells) in 37 % of patients; after therapy in 66 % of these patients, the rhinocytogram was normal. Our results suggest, according to the literature data, that SPA therapy with radioactive water could represent an alternative choice in chronic inflammatory diseases of the upper airways, nonresponsive to pharmacological therapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Shedden A (2005) Impact of nasal congestion on quality of life and work productivity in allergic rhinitis: findings from a large online survey. Treat Respir Med 4:439–446

    Google Scholar 

  2. Kennedy DW (1995) International conference on sinus disease: terminology, staging and therapy. Ann Otol Rhinol Laryngol 104(S167):1–31

    Google Scholar 

  3. Diamond G, Legarda D, Ryan LK (2000) The innate immune response of the respiratory epithelium. Immunol Rev 173:27–38

    Article  PubMed  CAS  Google Scholar 

  4. Fokkens WJ, Scheeren RA (2000) Upper airway defence mechanisms. Paediatr Resp Rev 1:336–341

    Article  CAS  Google Scholar 

  5. Vareille M, Kieninger E, Edwards MR, Regamey N (2011) The airway epithelium: soldier in the fight against respiratory viruses. Clin Microbiol Rev 24(1):210–229

    Article  PubMed  CAS  Google Scholar 

  6. Staffieri A, Abramo A (2007) Sulphurous-arsenical-ferruginous (thermal) water inhalations reduce nasal respiratory resistance and improve mucociliary clearance in patients with chronic sinonasal disease: preliminary outcomes. Acta Otolaryngol 127(6):613–617

    Article  PubMed  CAS  Google Scholar 

  7. Passali D, Bellussi L, De Benedetto M, Giordano C, Mira E, Paludetti G, Saglione F (2006) Crenotherapy and upper airways diseases. Acta Otorhinolaryngol Ital 26(4):5–54

    Google Scholar 

  8. Marullo T, Abramo A (2000) Effetti di un ciclo di crenoterapia inalatoria con oligominerali fluoridrati radioattivi. Acta Otorhinolaryngol Ital 20(63):1–13

    PubMed  CAS  Google Scholar 

  9. Grossman J (1997) One airway, one disease. Chest 111:118–168

    Article  Google Scholar 

  10. Corren J, Adinoff A, Irvin C (1992) Changes in bronchial responsiveness following nasal provocation with allergen. J Allergy Clin Immunol 89:611–618

    Article  PubMed  CAS  Google Scholar 

  11. Oliveira CAA, Sole D, Naspitz CK, Rachelefsky GS (1997) Improvement of bronchial hyper-responsiveness in asthmatic children treated for concomitant sinusitis. Ann Allergy Asthma Immunol 79:70–74

    Article  PubMed  CAS  Google Scholar 

  12. Dunlop G, Scadding GK, Lund VJ (1999) Effect of endoscopic sinus surgery on asthma management in patients with chronic rhinosinusitis, nasal polyposis and asthma. Am J Rhinol 13(4):261–265

    Article  PubMed  CAS  Google Scholar 

  13. Clement PAR, Gordon F (2005) Consensus report on acoustic rhinometry and rhinomanometry. Rhinology 43:169–179

    PubMed  CAS  Google Scholar 

  14. Eccles EA (2011) Guide to practical aspects of measurement of human nasal airflow by rhinomanometry. Rhinology 49:2–10

    PubMed  CAS  Google Scholar 

  15. Passàli D, Mezzedimi C, Passàli GC, Nuti D, Bellussi L (2000) The role of rhinomanometry, acoustic rhinometry, and mucociliary transport time in the assessment of nasal patency. Ear Nose Throat J 79(5):397–400

    PubMed  Google Scholar 

  16. Meltzer EO, Jalowayski AA (1988) Nasal cytology in clinical practice. Am J Rhinology 2:47–54

    Article  Google Scholar 

  17. Bousquet J, Van Cauwenberge P, Khaltaev N, Aria Workshop Group, World Health Organization (2001) Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 108(5 Suppl):S147–S334

    Google Scholar 

  18. van Cauwenberge P, Bachert C, Passalacqua G, Bousquet J, Canonica GW, Durham SR, Fokkens WJ, Howarth PH, Lund V, Malling HJ, Mygind N, Passali D, Scadding GK, Wang DY (2000) Consensus statement on the treatment of allergic rhinitis. European Academy of Allergology and Clinical Immunology. Allergy 55(2):116–134

    Article  PubMed  Google Scholar 

  19. Salami A, Dellepiane M, Crippa B, Mora F, Guastini L, Jankowska B, Mora R (2008) Sulphurous water inhalations in the prophylaxis of recurrent upper respiratory tract infections. Int J Pediatr Otorhinolaryngol 72(11):1717–1722

    Article  PubMed  Google Scholar 

  20. Costantino M, Lampa E, Nappi G (2006) Effectiveness of sulphur spa therapy with politzer in the treatment of rhinogenic deafness. Acta Otorhinolaryngol Ital 26:7–13

    PubMed  CAS  Google Scholar 

  21. Salami A, Dellepiane M, Strinati F, Guastini L, Mora R (2010) Sulphurous thermal water inhalations in the treatment of chronic rhinosinusitis. Rhinology 48(1):71–76

    PubMed  Google Scholar 

  22. Passali D, Bellussi L, Bianchini Ciampoli M, De Seta E (1984) Experiences in the determination of nasal mucociliary transport time. Acta Otolaryngol 97(3–4):319–323

    Article  PubMed  CAS  Google Scholar 

  23. Puchelle E, Aug F, Pham QT, Bertrand A (1981) Comparison of three methods for measuring nasal mucociliary clearance in man. Acta Otolaryngol 91(3–4):297–303

    Article  PubMed  CAS  Google Scholar 

  24. Boatsman JE, Calhoun KH, Ryan MW (2006) Relationship between rhinosinusitis symptoms and mucociliary clearance time. Otolaryngol Head Neck Surg 134(3):491–493

    Article  PubMed  Google Scholar 

  25. Arnaoutakis D, Collins WO (2011) Correlation of mucociliary clearance and symptomatology before and after adenoidectomy in children. Int J Pediatr Otorhinolaryngol 75(10):1318–1321

    Article  PubMed  Google Scholar 

  26. Passàli D, Ferri R, Becchini G, Passàli GC, Bellussi L (1999) Alterations of nasal mucociliary transport in patients with hypertrophy of the inferior turbinates, deviations of the nasal septum and chronic sinusitis. Eur Arch Otorhinolaryngol 256(7):335–337

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to D. Passali.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Passali, D., De Corso, E., Platzgummer, S. et al. SPA therapy of upper respiratory tract inflammations. Eur Arch Otorhinolaryngol 270, 565–570 (2013). https://doi.org/10.1007/s00405-012-2024-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-012-2024-5

Keywords

Navigation