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Genetics of hearing loss: where are we standing now?

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Abstract

Hearing loss (HL) is the most common sensory impairment and is caused by a broad range of inherited to environmental causes. Inherited HL consists 50–60% of all HL cases. The inherited form of HL is further classified to different categories. More than 300 syndromes and 40 genes have been identified to result in different levels of HL. Although several diagnostic or screening tests have been developed, yet there are controversies around their use.

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Authors and Affiliations

  1. Department of Otolaryngology Head and Neck Surgery, University of California, Irvine, 101 The City Drive South, Bldg 56, Suite 500, Rt 81, Orange, CA, 92868, USA

    Hossein Mahboubi, Sami Dwabe, Matthew Fradkin & Hamid R. Djalilian

  2. Department of Pediatrics, University of California, Irvine, Orange, USA

    Virginia Kimonis

Authors
  1. Hossein Mahboubi
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  2. Sami Dwabe
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  3. Matthew Fradkin
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  4. Virginia Kimonis
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  5. Hamid R. Djalilian
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Correspondence to Hamid R. Djalilian.

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Mahboubi, H., Dwabe, S., Fradkin, M. et al. Genetics of hearing loss: where are we standing now?. Eur Arch Otorhinolaryngol 269, 1733–1745 (2012). https://doi.org/10.1007/s00405-011-1910-6

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  • DOI: https://doi.org/10.1007/s00405-011-1910-6

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