Abstract
The objective of the study is to assess the role of diode laser coupled with topical mitomycin C (MMC) in the management of synechia after endoscopic sinus surgery. Twenty-five patients with recurrent sinusitis due to synechia between the middle turbinate and lateral nasal wall after endoscopic sinus surgery were included in this study. Diode laser was used to divide the synechia and MMC was applied topically in the area of the middle meatus for 5 min. Patients were followed for 6 months to assess symptoms improvement, recurrence of synechia and CT scan changes. Most of our patients reported improvement of their symptoms, recurrent synechia occurred in 15% of the patients with significant improvement of the CT scan findings. In conclusion, the diode laser with topical MMC is an outpatient procedure which is simple, safe and effective in managing postoperative nasal synechia.
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References
Fernandes SV (1999) Postoperative care in functional endoscopic sinus surgery. Laryngoscope 109:945–948
Gross RD, Sheridan MF, Burgess LP (1997) Endoscopic sinus surgery complications in residency. Laryngoscope 107:1080–1085
Van Duyne J, Coleman JA Jr (1995) Treatment of nasopharyngeal inlet stenosis following uvulopalatopharyngoplasty with the CO2 laser. Laryngoscope 105:914–918
Levine HL (1989) Endoscopy and the KTP/532 laser for nasal sinus disease. Ann Otol Rhinol Laryngol 98:46–51
Feyh J (1995) Endoscopic surgery of the nose and paranasal sinuses with the aid of the holmium:YAG laser. Adv Otorhinolaryngol 49:122–124
Muntz HR (1987) Pitfalls to laser correction of choanal atresia. Ann Otol Rhinol Laryngol 96:43–46
Costa VP, Spaeth GL, Eiferman RA et al (1993) Wound healing modulation in glaucoma filtration surgery. Ophthalmic Surg 24:152–166
Majmudar PA, Forstot SL, Dennis RF et al (2000) Topical mitomycin C for subepithelial fibrosis after refractive corneal surgery. Ophthalmology 107:89–94
Correa AJ, Reinisch L, Sanders DL et al (1999) Inhibition of subglottic stenosis with mitomycin C in the canine model. Ann Otol Rhinol Laryngol 108:1053–1060
Tom LWC, Palasti S, Potsic WP et al (1997) The effects of gelatin film stents in the middle meatus. Am J Rhinol 229–232
Friedman M, Landsberg R, Tanyeri H (2000) Middle turbinate medialization and preservation in endoscopic sinus surgery. Otolaryngol Head Neck Surg 123:76–80
Miller RS, Steward DL, Tami TA et al (2003) The clinical effects of hyaluronic acid ester nasal dressing (Merogel) on intranasal wound healing after functional endoscopic sinus surgery. Otolaryngol Head Neck Surg 128(6):862–869
Chung JH, Cosenza MJ, Rahbar R, Metson RB (2002) Mitomycin C for the prevention of adhesion formation after endoscopic sinus surgery: a randomized, controlled study. Otolaryngol Head Neck Surg 126(5):468–474
Lee JY, Lee SW (2007) Preventing lateral synechia formation after endoscopic sinus surgery with a silastic sheet. Arch Otolaryngol Head Neck Surg 133(8):776–779
Shrime MG, Tabaee A, Hsu AK et al (2007) Synechia formation after endoscopic sinus surgery and middle turbinate medialization with and without FloSeal. Am J Rhinol 21(2):174–179
Konstantinidis I, Tsakiropoulou E, Vital I et al (2008) Intra- and postoperative application of mitomycin C in the middle meatus reduces adhesions and antrostomy stenosis after FESS. Rhinology 46(2):107–111
Anand VK, Tabaee A, Kacker A et al (2004) The role of mitomycin C in preventing synechia and stenosis after endoscopic sinus surgery. Am J Rhinol 18(5):311–314
Kao SCS, Liao CL, Tseng JHS et al (1996) Dacryocystorhinostomy with intraoperative mitomycin C. Ophthalmology 104:86–91
Hueman EM, Simpson CB (2005) Airway complications from topical mitomycin C. Otolaryngol Head Neck Surg 133:831–835
Hu D, Sires BS, Tong DC et al (2000) Effect of brief exposure to mitomycin C on cultured human nasal mucosa fibroblasts. Ophthal Plast Reconstr Surg 16:119–125
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The authors would like to thank Dr Ahmed Saada, MD, for his help in photography.
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Hesham, A., Fathi, A., Attia, M. et al. Laser and topical mitomycin C for management of nasal synechia after FESS: a preliminary report. Eur Arch Otorhinolaryngol 268, 1289–1292 (2011). https://doi.org/10.1007/s00405-011-1587-x
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DOI: https://doi.org/10.1007/s00405-011-1587-x