Abstract
Cholesterol granuloma (CG) of the maxillary sinus is very rare. In this study, the searching of the literature was performed with the keywords of cholesterol granuloma and maxillary sinus. All retrieved literature were reviewed throughout to identify and analyze all individual characteristics. Two additional cases in our hospital were also included. The result showed that, in the overall 37 cases, the ratio of male to female was about 3:1. Caucasian (14/37) and Turkish (10/37) were reported more frequently. CG of maxillary sinus had an opposite sex predilection compared with the fungus balls of the maxillary sinus. In addition, the comorbidity of these two diseases was found only in one patient in the literature. These results suggested that the different mechanisms other than poor aeration of the maxillary sinus played a role in the formation of CG of maxillary sinus. The diagnosis for CG of the maxillary sinus before operation is difficult, but the clear golden yellow rhinorrhea and hemorrhagic signs may provide a good diagnostic evidence. The symptoms were vague and about half of the patients presented with non-specific symptoms. Therefore, it seemed reasonable that CG of the maxillary sinus was under diagnosed in the clinical practice. Treatment consists of complete excision via Caldwell–Luc or endoscopic approach and provides a good prognosis. Bilateral involvements are rare but possible in this disease entity.
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References
Graham J, Michaels L (1978) Cholesterol granuloma of the maxillary antrum. Clin Otolaryngol 3:155–160
Hellquist H, Lundgren J, Olofsson J (1984) Cholesterol granuloma of the maxillary and frontal sinuses. ORL J Otorhinolaryngol Relat Spec 46:153–158
Milton CM, Bickerton RC (1986) A review of maxillary sinus cholesterol granuloma. Br J Oral Maxillofac Surg 24:293–299
Gatland DJ, Youngs RP, Jeffrey IJ (1988) Cholesterol granuloma of the maxillary antrum. J Otolaryngol 17:131–133
Gunes HA, Almac A, Canbay E (1988) Cholesterol granuloma of the maxillary antrum. J Laryngol Otol 102:630–632
Rath-Wolfson L, Talmi YP, Halpern M, Levit I, Zohar Y, Gal R (1993) Cholesterol granulomas of the maxillary sinus presenting with nasal obstruction. Otolaryngol Head Neck Surg 109:956–958
Erpek G, Ustun H (1994) Cholesterol granuloma in the maxillary sinus. Eur Arch Otorhinolaryngol 251:246–247
Dilek FH, Kiris M, Ugras S (1997) Cholesterol granuloma of the maxillary sinus. A case report. Rhinology 35:140–141
Kunt T, Ozturkcan S, Egilmez R (1998) Cholesterol granuloma of the maxillary sinus: six cases from the same region. J Laryngol Otol 112:65–68
Xu W, Jin X (1998) Cholesterol granuloma of the maxillary sinus: 2 cases report. Lin Chuang Er Bi Yan Hou Ke Za Zhi 12:549–551
Sarioglu S, Pabuccuoglu U, Arzu Topal N (2001) Cholesterol granuloma and aspergilloma of the maxillary sinus. Eur Arch Otorhinolaryngol 258:74–76
Leon ME, Chavez C, Fyfe B, Nagorsky MJ, Garcia FU (2002) Cholesterol granuloma of the maxillary sinus. Arch Pathol Lab Med 126:217–219
Kikuchi T, So E, Ishimaru K, Miyabe Y, Abe K, Kobayashi T (2002) Endoscopic sinus surgery in cases of cholesterol granuloma of the maxillary sinus. Tohoku J Exp Med 197:233–237
Tzerbos FH, Mavrogeorgis A, Kavantzas NG, Bollas N (1994) A cholesterol granuloma in the maxillary sinus: report of case. J Oral Maxillofac Surg 52:1205–1207
Marks SC, Smith DM (1995) Endoscopic treatment of maxillary sinus cholesterol granuloma. Laryngoscope 105:551–552
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Chao, TK. Cholesterol granuloma of the maxillary sinus. Eur Arch Otorhinolaryngol 263, 592–597 (2006). https://doi.org/10.1007/s00405-006-0015-0
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DOI: https://doi.org/10.1007/s00405-006-0015-0