Abstract
Purpose
The link between endometriosis and the presence or intensity of pain is controversial. The aim of the present study was to assess the relationship between chronic pelvic pain (CPP) and severity of endometriosis and the effectiveness of laparoscopic treatment in a 6-month follow-up.
Methods
Prospective observational study in a referral unit. 144 women had laparoscopy to investigate CPP. Symptoms were assessed by a 10-point visual analog scale. The main outcome measure was the frequency and intensity of CPP.
Results
No difference in pain was found between women with and without endometriosis. Advanced endometriosis was associated with dysmenorrhea, deep endometriosis with dyspareunia and rectovaginal disease with dyschezia. Laparoscopic treatment improves symptoms.
Conclusions
Women with severe endometriosis are more likely to report severe dysmenorrhoea. Furthermore location of endometriosis in the rectovaginal space is associated with dyschezia and deep endometriosis with dyspareunia. However, the association between presence and stage of endometriosis and severity of symptoms is marginal.
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References
Ballard K, Seaman H, de Vries C, Wright J (2008) Can symptomatology help in the diagnosis of endometriosis? Findings from a national case control study. Part 1. Br J Obstet Gynaecol 115:1382–1391
Moen MH, Muus KM (1991) Endometriosis in pregnant and non-pregnant women at tubal sterilization. Hum Reprod 6:699–702
Howard FM (1993) The role of laparoscopy in chronic pelvic pain: promise and pitfalls. Obstet Gynecol Surv 48:357–387
The American Fertility Society (1985) Revised American fertility society classification of endometriosis. Fertil Steril 43:351–352
Brosens I, Donnez J, Benagiano G (1993) Improving the classification of endometriosis. Hum Reprod 8:1792–1795
Abbott JA, Hawe J, Clayton RD, Garry R (2003) The effects and effectiveness of laparoscopic excision of endometriosis: a prospective study with 2–5 year follow-up. Hum Reprod 18:1922–1927
Wright J, Lotfallah H, Jones K, Lovell D (2005) A randomized trial of excision versus ablation for mild endometriosis. Fertil Steril 83:1830–1836
Healey M, Cheng C, Kaur H (2014) To excise or ablate endometriosis? A prospective randomized double-blinded trial after 5-year follow-up. J Minim Invasive Gynecol 21(6):999–1004
Wykes C, Clark T, Khan K (2004) Accuracy of laparoscopy in the diagnosis of endometriosis: a systematic quantitative review. BJOG 111:1204–1212
Shafik A, Ratcliffe N, Wright J (2000) The importance of histological diagnosis in patients with chronic pelvic pain and laparoscopic evidence of endometriosis. Gynaecol Endosc 9:301–304
Chopin N, Vieira M, Borghese B, Foulot H, Dousset B, Coste J, Mignon A, Fauconnier A, Chapron C (2005) Operative management of deeply infiltrating endometriosis: results on pelvic pain symptoms according to a surgical classification. J Minim Invasive Gynecol 12:106–112
Banerjee S, Ballard KD, Lovell DP, Wright J (2006) Deep and superficial endometriotic disease: the response to radical laparoscopic excision in the treatment of chronic pelvic pain. Gynecol Surg 3:199–205
Lukic A, Di Properzio M, De Carlo S, Nobili F, Schimberni M, Bianchi P, Prestigiacomo C, Moscarini M, Caserta D (2015) Quality of sex life in endometriosis patients with deep dyspareunia before and after laparoscopic treatment. Arch Gynecol Obstet. doi:10.1007/s00404-015-3832-9
Ford J, English J, Miles WA, Giannopoulos T (2004) Pain, quality of life and complications following the radical resection of rectovaginal endometriosis. BJOG 111:353–356
Wright JT, Shafik A (2001) Quality of life following radical excision of rectovaginal endometriosis associated with complete obliteration of the posterior cul de sac. Gynaecol Endosc 10:107–110
Garry R, Clayton R, Hawe J (2000) The effect of endometriosis and its radical laparoscopic excision on quality of life indicators. BJOG 107:44–54
Fedele L, Bianchi S, Zanconato G, Bettoni G, Gotsch F (2004) Long-term follow-up after conservative surgery for rectovaginal endometriosis. Am J Obstet Gynecol 190:1020–1024
European Society of Human Reproduction and Embryology (2014) ESHRE guideline: management of women with endometriosis. Hum Reprod 29:400–412
Abbott J, Hawe J, Hunter D, Holmes M, Finn Garry R (2004) Laparoscopic excision of endometriosis: a randomized, placebo-controlled trial. Fertil Steril 82:878–884
Sampson JA (1927) Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity. Am J Obstet Gynecol 14:422–425
Koninckx PR, Meuleman C, Demeyere S, Lesaffre E, Cornillie FJ (1991) Suggestive evidence that pelvic endometriosis is a progressive disease, whereas deeply infiltrating endometriosis is associated with pelvic pain. Fertil Steril 55:759–765
Vercellini P, Fedele L, Aimi G, Pietropaolo G, Consonni D, Crosignani P (2007) Association between endometriosis stage, lesion type, patient characteristics and severity of pelvic pain symptoms: a multivariate analysis of over 1000 patients. Hum Reprod 22:266–271
Haas D, Chvatal R, Reichert B, Renner S, Shebl O, Binder H, Wurm P, Oppelt P (2012) Endometriosis: a premenopausal disease? Age pattern in 42,079 patients with endometriosis. Arch Gynecol Obstet 286:667–670
Vercellini P, Trespidi L, De Giorgi O, Cortesi I, Parazzini F, Crosignani PG (1996) Endometriosis and pelvic pain: relation to disease stage and localization. Fertil Steril 65:299–304
Harrison RF, Barry-Kinsella C (2000) Efficacy of medroxyprogesterone treatment in infertile women with endometriosis: a prospective, randomized, placebo-controlled study. Fertil Steril 74:24–30
Fauconnier A, Chapron C (2005) Endometriosis and pelvic pain: epidemiological evidence of the relationship and implications. Hum Reprod 11:595–606
Popora M, Koninckx P, Piazze J, Natili M, Colagrande S, Cosmi E (1999) Correlation between endometriosis and pelvic pain. J Am Assoc Gynecol Laparosc 6:429–434
Fedele L, Parazzini F, Bianchi S, Arcaini L, Candiani GB (1990) Stage and localization of pelvic endometriosis and pain. Fertil Steril 53:155–158
Fauconnier A, Chapron C, Dubuisson JB, Vieira M, Dousset B, Breart G (2002) Relation between pain symptoms and the anatomic location of deep infiltrating endometriosis. Fertil Steril 78:719–726
Ferrero S, Abbamonte LH, Giordano M, Ragni N, Remorgida V (2007) Deep dyspareunia and sex life after laparoscopic excision of endometriosis. Hum Reprod 22:1142–1148
Gruppo Italiano per lo Studio dell’ Endometriosi (2001) Relationship between stage site and morphological characteristics of pelvic endometriosis and pain. Hum Reprod 16:2668–2671
Duffy JM, Arambage K, Correa FJ, Olive D, Farquhar C, Garry R, Barlow DH, Jacobson TZ (2014) Laparoscopic surgery for endometriosis. Cochrane Database Syst Rev. doi:10.1002/14651858.CD011031.pub2
Ballard K, Lane H, Hudelist G, Banerjee S, Wright J (2010) Can specific pain symptoms help in the diagnosis of endometriosis? A cohort study of women with chronic pelvic pain. Fertil Steril 94:20–27
Ballard KD, Lowton K, Wright J (2006) What’s the delay? A qualitative study of women’s experience of reaching a diagnosis of endometriosis. Fertil Steril 85:1296–1301
Deguara CS, Pepas L, Davis C (2012) Does minimally invasive surgery for endometriosis improve pelvic symptoms and quality of life? Curr Opin Obstet Gynecol 24:241–244
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Apostolopoulos, N.V., Alexandraki, K.I., Gorry, A. et al. Association between chronic pelvic pain symptoms and the presence of endometriosis. Arch Gynecol Obstet 293, 439–445 (2016). https://doi.org/10.1007/s00404-015-3855-2
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DOI: https://doi.org/10.1007/s00404-015-3855-2