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Intracavitary physiotherapy is not inferior to endometrial scratching in patients with recurrent implantation failure

  • Gynecologic Endocrinology and Reproductive Medicine
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Purpose

To investigate whether intracavitary physiotherapy is superior to endometrial scratching in patients with recurrent implantation failure (RIF) after in vitro fertilization/intracytoplasmic sperm injection- embryo transfer (IVF/ICSI-ET) cycles.

Methods

According to the inclusion criteria defined by our hospital, 63 patients with RIF were included in the retrospective study. 20 patients who received intracavitary physiotherapy were classified into Group A, 8 patients with both intracavitary physiotherapy and endometrial scratching were into Group B, and 35 patients who underwent endometrial scratching were into Group C. The primary outcome measures were implantation and clinical pregnancy rates. The secondary outcome measure was pregnancy outcome.

Results

There were no statistical differences in implantation and clinical pregnancy rates between Groups A and C (29.41 vs 35.59 %, 45.00 vs 48.57 % respectively, P > 0.05), Groups B and C (36.36 vs 35.59 %, 50.00 vs 48.57 % respectively, P > 0.05). In addition, no statistical differences were discovered in pregnancy outcomes between Groups A and C (P > 0.05), Groups B and C (P > 0.05).

Conclusions

Intracavitary physiotherapy is not inferior to endometrial scratching on improving implantation and clinical pregnancy rates in patients with RIF after IVF/ICSI cycles.

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Acknowledgments

This study was financially supported by the National Basic Research Program of China (973 program) (2011CB944502, 2012CB944700) and Science research foundation item of no-earnings health vocation (201002013).

Conflict of interest

We declare that there are no conflicts of interest.

Author information

Authors and Affiliations

  1. Center for Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, China

    Qian Zhang, Bo Zhang, Junhao Yan, Chu Zhang, Rong Tang, Yan Sheng, Na Wang & Zi-Jiang Chen

  2. National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, China

    Qian Zhang, Junhao Yan, Chu Zhang, Rong Tang, Yan Sheng, Na Wang & Zi-Jiang Chen

  3. The Key Laboratory for Reproductive Endocrinology of Ministry of Education, Jinan, China

    Qian Zhang, Junhao Yan, Chu Zhang, Rong Tang, Yan Sheng, Na Wang & Zi-Jiang Chen

  4. Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan, China

    Qian Zhang, Junhao Yan, Chu Zhang, Rong Tang, Yan Sheng, Na Wang & Zi-Jiang Chen

  5. Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Zi-Jiang Chen

  6. Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China

    Zi-Jiang Chen

  7. Reproductive Medicine Center, Zhongnan Hospital, Wuhan University, Wuhan, China

    Bo Zhang

Authors
  1. Qian Zhang
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  2. Bo Zhang
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  3. Junhao Yan
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  4. Chu Zhang
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  5. Rong Tang
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  6. Yan Sheng
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  7. Na Wang
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  8. Zi-Jiang Chen
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Corresponding author

Correspondence to Zi-Jiang Chen.

Additional information

Q. Zhang and B. Zhang both the authors contributed equally to this work.

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Zhang, Q., Zhang, B., Yan, J. et al. Intracavitary physiotherapy is not inferior to endometrial scratching in patients with recurrent implantation failure. Arch Gynecol Obstet 291, 173–177 (2015). https://doi.org/10.1007/s00404-014-3382-6

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  • DOI: https://doi.org/10.1007/s00404-014-3382-6

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