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Effect of high-intensity focused ultrasound on sexual function in the treatment of uterine fibroids: comparison to conventional myomectomy

  • Gynecologic Oncology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Background

Uterine fibroids are the most common benign tumors in women. As a new minimally invasive clinical technology, high-intensity focused ultrasound (HIFU) has been widely applied to the treatment of uterine fibroids, but no study using objective criteria has evaluated the effect of HIFU on sexual function.

Methods

A total of 100 premenopausal patients were enrolled in this randomized clinical trial (RCT). The brief index of sexual functioning (BISF-W) was used to evaluate changes in sexual function. Differences in the outcome were calculated for each individual before treatment and at 3 and 6 months after treatment, and changes were compared between the HIFU group (HIFUG) and the myomectomy group (MYG).

Results

Preoperative BISF-W scores were similar in both groups (P < 0.05). No significant differences were found between the two groups at 3 and 6 month after treatment. Within the groups, patients reported less arousal and less problems at 3 month compared to baseline. There was a trend toward improved sexual satisfaction and overall quality of sexual life in both groups 6 months after treatment compared with the baseline, although it failed to reach statistical significance except for the dimensions of relational satisfaction and problems affecting sexuality.

Conclusions

Sexual function improved on average to some degree after both HIFU and conventional myomectomy.

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Acknowledgments

This study was supported by the Grants from the National Natural Science Foundation of China (Grant No: 30901234) and the Scientific and Technological Project of Chongqing (No: CSTC, 2010AB5122).

Conflict of interest

  We declare that we have no conflict of interest.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, First Affiliated Hospital, Chongqing Medical University, 1 Yi Xue Yuan Road, Yu Zhong District, Chongqing, 400016, People’s Republic of China

    Xiaoyan Wang, Lifang Wang & Liangdan Tang

  2. Maternal and Child care service Centre, Guiyang, 550003, Guizhou, People’s Republic of China

    Juan Qin

  3. Institute of Ultrasound Engineering in Medicine, First Affiliated Hospital, Chongqing Medical University, Chongqing, 400016, People’s Republic of China

    Jinyun Chen & Wenzhi Chen

Authors
  1. Xiaoyan Wang
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  2. Juan Qin
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  3. Lifang Wang
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  4. Jinyun Chen
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  5. Wenzhi Chen
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  6. Liangdan Tang
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Corresponding author

Correspondence to Liangdan Tang.

Additional information

X. Wang and J. Qin contributed equally to this article.

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Wang, X., Qin, J., Wang, L. et al. Effect of high-intensity focused ultrasound on sexual function in the treatment of uterine fibroids: comparison to conventional myomectomy. Arch Gynecol Obstet 288, 851–858 (2013). https://doi.org/10.1007/s00404-013-2775-2

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  • DOI: https://doi.org/10.1007/s00404-013-2775-2

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