Abstract
Introduction
Nasal glioma is a rare, benign congenital midline facial lesion.
Materials and methods
Prenatal ultrasound diagnosis performed at 2nd trimester of pregnancy revealed a right-sided mass at the level of the fetal face extending from the right internal canthus to the nasal bridge.
Conclusion
Differential diagnosis of facial mass in the fetus represents a critical issue because is essential in guiding the prenatal counselling of the couple and in guiding the prenatal and/or postnatal management. Alternative diagnoses such as dacryocystocele, dermoid cyst, retinoblastoma or teratoma, hemangioma, and encephalocele that can not completely be excluded prenatally are discussed. Embryology, pathology, prenatal ultrasound diagnostic clusters of the lesion as well as MR imaging findings are discussed together with review of the literature.
References
Strauss RB, Callicott JH, Hargett IR (1966) Intranasal heterotopia. So-called nasal glioma. Am J Dis Child 111:317–320
Fletcher C (ed) (2007) Diagnostic Histopathology of Tumors. 3rd edn. vol 1. Chapt 4. Churchill Livingstone Elsevier, Philadelphia, p 135
Riffaud L, Ndikumana R, Azzis O, Cadre B (2008) Glial heterotipia of the face. J Pediatr Surg 43:e1–e3
De Biasio P, Scarso E, Prefumo F, Odella C, Rossi A, Venturini PL (2006) Prenatal diagnosis of a nasal glioma in the mid trimester. Ultrasound Obstet Gynecol 27:571–573
Grzegorezyk V, Brausser-Daudruy M, Labadie G, Cellier C, Verspyck E (2010) Prenatal diagnosis of a nasal glioma. Pediatr Radiol. doi:10.1007/s00247-010-1642-6
Chmait RH, Pretorius DH, Hull AD (2002) Picture of the month. Ultrasound Obstet Gynecol 20:417–418
Charrier JB, Leboulanger N, Roger G, Denoyelle F, Garabédian EN, Monteil JP (2006) Nasal glioma heterotopia: embryological and clinical approaches. Rev Stomatol Chir Maxillofac 107:44–49
Fitzpatrick E, Miller RH (1996) Congenital midline masses: dermoids, gliomas, and encephaloceles. J State Med Soc 148:93–96
Maat-Kievit JA, Oepkes D, Hartwig NG, Vermeij-Keers C, van Kamp IL, van de Kamp JJ (1993) A large retinoblastoma detected in a fetus at 21 weeks of gestation. Prenat Diagn 13:377–384
Sepulveda W, Wojakowski AB, Elias D, Otaño L, Gutierrez J (2005) Congenital dacryocystocele. Prenatal 2- and 3-dimensional sonographic findings. J Ultrasound Med 24:225–230
Sharony R, Raz J, Aviram R, Cohen I, Beyth Y, Tepper T (1999) Prenatal diagnosis of dacryocystocele: a possible marker for syndrome. Ultrasound Obstet Gynecol 14:71–73
Castillo M (1994) Congenital abnormalities of the nose: CT and MR findings. AJR 162:1211–1217
Benacerraf BR (1999) A nasal tip teratoma. Ultrasound Obstet Gynecol 14:222
Dasgupta NR, Bentz ML (2003) Nasal gliomas: identification and differentiation from hemangiomas. J Craniofac Surg 14:736–738
Bronshtein M, Bar-Hava I, Blumenfeld Z (1992) Early second-trimester sonographic appearance of occipital hemangioma simulating encephalocele. Prenat Diagn 12:695–698
Gorincour G, Kokta V, Rypens F, Garel L, Powell J, Dubois J (2005) Imaging characteristics of two subtypes of congenital hemangiomas: rapidly involuting congenital hemangiomas and non-involving congenital hemangiomas. Pediatr Radiol 35:1178–1185
Elia D, Garel C, Enjolras O, Vermouneix L, Soupre V, Oury JF, Guibaud L (2008) Prenatal imaging findings in rapidly involuting congenital hemangioma of the skull. Ultrasound Obstet Gynecol 31:572–575
Wu CL, Tsao LY, Yang AD, Chen MK (2008) Endoscopic surgery for nasal glioma mimicking encephalocele in infancy. Skull Base 18:401–404
Park YH, Kim SW, Cho SH, Choi YW (2010) Nasopharyngeal glioma causing respiratory distress in a neonate: transoral endoscopic excision. Ear Nose Throat 89:E11–E13
Cerdá-Nicolá M, Sanchez Fernandez de Sevilla C, Lopez-Ginés C, Peydro-Olaya A, Llombart-Bosch A (2002) Nasal glioma or nasal glial heterotopia? Morphological, immunohistochemical and ultrastructural study of two cases. Clin Neuropathol 21:66–71
Huisman TA, Schneider JF, Kellenberger CJ, Martin-Fiori E, Willi UV, Holzman D (2004) Developmental nasal midline masses in children: neuroradiological evaluation. Eur Radiol 14:243–249
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Tonni, G., Lituania, M., Bonasoni, M.P. et al. Prenatal ultrasound and histological diagnosis of fetal nasal glioma (heterotopic central nervous system tissue): report of a new case and review of the literature. Arch Gynecol Obstet 283 (Suppl 1), 55–59 (2011). https://doi.org/10.1007/s00404-011-1856-3
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DOI: https://doi.org/10.1007/s00404-011-1856-3