Abstract
Headache in late pregnancy is warning of the presence of severe and/or lethal disorders. Here, we present a case of Vogt–Koyanagi–Harada disease (VKH), in which headache was the preceding and predominant symptom. At 37 weeks of pregnancy, a Japanese 1-para woman with an uneventful pregnancy complained of severe headache and then blurred vision. Although we initially diagnosed this condition as pregnancy-associated retinal detachment, headache and blurred vision persisted after delivery. Eye anterior segment lesions appeared and VKH disease was diagnosed, with systemic steroid administration completely ameliorating both the headache and visual disturbance. Obstetricians must be aware that headache may be the first sign of VKH disease.
References
Rao KP, Rao NA (2006) Vogt–Koyanagi–Harada Disease. In: Ryan SJ, Hinton DR, Schachat AP, Wilkinson P (eds) Retina, 4th edn. Elsevier Mosby, Maryland, pp 1827–1837
Sunness JS, Haller JA, Fine SL (1993) Central serous chorioretinopathy and pregnancy. Arch Ophthalmol 111:360–364
Rezai KA, Eliott D (2004) Optical coherence tomographic findings in pregnancy-associated central serous chorioretinopathy. Graefes Arch Clin Exp Ophthalmol 242:1014–1016
Ohkawara Y, Makino S (2009) A case of Vogt–Koyanagi–Harada disease treated with systemic steroid administration after delivery in a patient at the 37th week of pregnancy. Folia Japonica de Ophthalmol Clin 2:616–619 (in Japanese)
Tien MC, Teoh SC (2009) Treatment of Vogt–Koyanagi–Harada syndrome in pregnancy. Can J Ophthalmol 44:211–212
Doi M, Matsubara H, Uji Y (2000) Vogt–Koyanagi–Harada syndrome in a pregnant patient treated with high-dose systemic corticosteroids. Acta Ophthalmol Scand 78:93–96
Tavsanli M, Uluduz D, Saip S, Kendiroglu G (2008) Vogt–Koyanagi–Harada disease: headache as an initial manifestation. J Headache Pain 9:255–256
Conflicts of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Matsubara, S., Kuwata, T., Ohkawara, Y. et al. Headache in late pregnancy: a symptom for Vogt–Koyanagi–Harada disease. Arch Gynecol Obstet 283, 1423–1425 (2011). https://doi.org/10.1007/s00404-010-1748-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00404-010-1748-y