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Cystic adenomatoid malformation of the lung causing hydrops fetalis: case report and review of the literature

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Abstract

Objective

Fetal congenital cystic adenomatoid malformation (CCAM) is a rare lung abnormality with a highly variable prognosis depended on the presence of fetal hydrops and the size of the cysts. In case of fetal hydrops the prognosis is fatal without intervention.

Methods and design

Case report and literature review.

Setting

We report on the ultrasound and pathological findings of a hydropic fetus due to a CCAM Type II at 22 weeks of gestation.

Conclusions

Congenital cystic adenomatoid malformation is a rare fetal lung disease with an excellent prognosis in the absence of fetal hydrops. CCAM associated with fetal hydrops carries a grave prognosis but survival rates of 70% can be achieved by thoraco-amniotic drainage in those with macrocystic lesions.

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Acknowledgment

We thank Professor Falko Fend for critical reading of the manuscript.

Conflict of interest statement

None.

Author information

Authors and Affiliations

  1. Institute of Pathology, University Hospital Tuebingen, Tübingen, Germany

    Sarah Schott & Susanne Mackensen-Haen

  2. Department of Obstetrics and Gynaecology, University Hospital Tuebingen, Tübingen, Germany

    Markus Wallwiener, Gabriele Meyberg-Solomayer & Karl Oliver Kagan

  3. Department of Pathology, University of Tuebingen, Liebermeisterstr 8, 72076, Tübingen, Germany

    Sarah Schott

Authors
  1. Sarah Schott
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  2. Susanne Mackensen-Haen
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  3. Markus Wallwiener
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  4. Gabriele Meyberg-Solomayer
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  5. Karl Oliver Kagan
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Corresponding author

Correspondence to Sarah Schott.

Additional information

S. Schott, G. Meyberg-Solomayer, and K. O. Kagan have contributed equally to the senior authorship.

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Schott, S., Mackensen-Haen, S., Wallwiener, M. et al. Cystic adenomatoid malformation of the lung causing hydrops fetalis: case report and review of the literature. Arch Gynecol Obstet 280, 293–296 (2009). https://doi.org/10.1007/s00404-008-0880-4

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  • DOI: https://doi.org/10.1007/s00404-008-0880-4

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