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Good pregnancy outcome after prenatal exposure to bleomycin, etoposide and cisplatin for ovarian immature teratoma: a case report and literature review

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Abstract

Aim

The administration of bleomycin plus etoposide and cisplatin during pregnancy is rare.

Materials and methods

We describe a case with good pregnancy outcome after exposure to these chemotherapeutic agents at the third trimester of pregnancy.

Results and discussion

A pregnant woman with stage IIIc immature teratoma underwent surgical staging, and received two cycles of bleomycin, etoposide and cisplatin from the 29th week of pregnancy until delivery. The patient did not have any evidence of recurrence of ovarian cancer for 1.5 years. Her infant did not have any evidence of minor or major malformations, and showed normal neurological development during 1.5 years of follow-up.

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Authors and Affiliations

  1. Gynecologic Oncology Department, Tehran University of Medical Sciences, Tehran, Iran 

    Nadereh Behtash & Mitra Modares Gilani

  2. Gynecologic Oncology Department, Vali-e-Asr Hospital, Imam Khomeini Hospital Complex, Keshavarz Blvd, Tehran, 14914, Iran

    Mojgan Karimi Zarchi

Authors
  1. Mojgan Karimi Zarchi
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  2. Nadereh Behtash
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  3. Mitra Modares Gilani
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Correspondence to Mojgan Karimi Zarchi.

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Karimi Zarchi, M., Behtash, N. & Modares Gilani, M. Good pregnancy outcome after prenatal exposure to bleomycin, etoposide and cisplatin for ovarian immature teratoma: a case report and literature review. Arch Gynecol Obstet 277, 75–78 (2008). https://doi.org/10.1007/s00404-007-0416-3

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  • DOI: https://doi.org/10.1007/s00404-007-0416-3

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