Abstract
Objective: The aim of the study was to evaluate if the diagnosis and treatment of uterine cavity abnormalities by hysteroscopy in patients undergoing IVF programme is of any value in improving clinical pregnancy outcome. Methods: 520 patients participated in this prospective randomized study and were classified into two groups. Group I (n = 265) without office hysteroscopy. Group II (n = 255) had office hysteroscopy and was sub classified into Group II a and Group II b. Group II a (n = 160) had normal hysteroscopic findings whereas Group II b (n = 95) had abnormal office hysteroscopy findings, which were corrected at the same time. Result: There was no difference in the mean number of oocytes retrieved, fertilization rate, and number of embryos transferred among the patients in different groups. Statistically significant difference was observed in terms of clinical pregnancy rates between Group I and Group II a (26.2 and 44.44%, P < 0.05), and Group I and Group II b (26.2 and 39.55%, P < 0.05), respectively. Conclusion: Patients with recurrent IVF embryo transfer failures after normal hysterosalpingography findings should also be reevaluated using hysteroscopy prior to further commencing IVF-embryo transfer cycles in order to enhance the clinical pregnancy rates.
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References
Cumming DC, Taylor PJ (1980) Combined laparoscopy and hysteroscopy in the investigation of the ovulatory female. Fertil Steril 33:475–478
Prevedourakis C, Loutradis D, Kalianidis C, Markis N, Asavantinos D (1994) Hysterosalpingography and hysteroscopy in female infertility. Hum Reprod 9:2353–2355
Linderman H, Mohr J (1976) CO2 hysteroscopy, diagnosis and treatment. Am J Obstet Gynecol 124:129–133
Valle RF (1980) Hysteroscopy in the evaluation of female infertility. Am J Obstet Gynecol 137:425–431
Kirsop R, Porter R, Torode H, Smith D, Saunders D (1991) The role of Hysteroscopy in patients having failed IVF/GIFT transfer cycles. Aust N Z J Obstet Gynaecol 31:2263–2264
Varasteh NN, Neuwirth RS, Levin B Keltz MD (1999) Pregnency rates after hysteroscopy polypectomy and myomectomy in infertile women. Obstet Gynaecol 42:276–289
Golan A, Eilat E, Ron-EL R Herman A, Soffer Y, Bukovsky I (1996) Hysteroscopy is superior to hysterosalpingography in infertility investigations. Acta Obstet Gynecol Scand 75:654–656
Wang CW, Lee CL, Lai YM Tsai CC, Chang MY, Soong YK (1996) Comparision of hysterosalpingography and hysteroscopy in female infertility. J Am Assoc Gynecol Laparosc 3:581–584
Cunha-Filho JSL, de Souza CAB, Salazar CC, Facin AC, Freitas FM, Passos EP (2001) Accuracy of hysterosalpingography and hysteroscopy for diagnosis of intrauterine lesions in infertile patients in an assisted fertilization programme. Gynaecol Endosc 10:45–48
Kessler I, Lancet M (1986) Hysterography and hysteroscopy, a comparision. Fertil Steril 46:709–710
Valle RF (1999) Office hysteroscopy. Clin Obstet Gynecol 42:276–289
Cicinelli E, Matteo M, Causio F, Schonauer LM, Pinto V, Galantino P (2001) Tolerability of the mini-pan-endoscopic approach (transvaginal hydrolaparoscopy and minihysteroscopy) versus hydrosalpingography in an outpatient infertility investigation. Fertil Steril 76:1048–1051
Shokeir TA, Shalan HM, Shafei MM (2004) Combined diagnostic approach of laparoscopy and hysteroscopy in the evaluation of female infertility: results of 612 patients. J Obstet Gynaecol Res 30:9–14
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Rama Raju, G.A., Shashi Kumari, G., Krishna, K.M. et al. Assessment of uterine cavity by hysteroscopy in assisted reproduction programme and its influence on pregnancy outcome. Arch Gynecol Obstet 274, 160–164 (2006). https://doi.org/10.1007/s00404-006-0174-7
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DOI: https://doi.org/10.1007/s00404-006-0174-7