Abstract
Methods
Circulating CA 125, CA 19-9, CA 15-3 and carcinoembryonic antigen (CEA) levels were studied in sixty patients with hydatidiform mole and in twenty normal pregnant women of a corresponding duration of pregnancy.
Discussion
Serum levels of CA 125, CA 15-3 and CEA are not affected by molar pregnancy. The mean level of CA 19-9 in maternal serum is significantly lower in cases of molar pregnancy when compared with cases of normal pregnancy. The amnion cell origin of CA 19-9 could explain the statistically significant difference between cases of therapeutic abortion and cases of HM (complete HM lacks amniotic membrane).
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Hegab, H.M., Schindler, A.E., Rizk, M. et al. Evaluation of tumour markers in molar pregnancy. Arch Gynecol Obstet 268, 151–154 (2003). https://doi.org/10.1007/s00404-003-0481-1
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DOI: https://doi.org/10.1007/s00404-003-0481-1