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In-hospital prognostic value of hemoglobin levels on admission in patients with acute ST segment elevation myocardial infarction undergoing primary angioplasty

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Abstract

Purpose

Anemia is a common comorbidity in patients presenting with ST-elevation myocardial infarction (STEMI). The aim of this study was to investigate the in-hospital prognostic value of admission hemoglobin (Hb) levels in patients with acute STEMI undergoing primary percutaneous coronary intervention (p-PCI).

Methods

This is a retrospective study of 1,625 patients with STEMI stratified by quartiles of admission Hb concentration (Q1 ≤12.5 g/dl, Q2 12.6–13.8 g/dl, Q3 13.9–15.0 g/dl, Q4 ≥15.1 g/dl). Main outcome measures were in-hospital rates of all cause mortality, re-infarction, target vessel revascularization, stroke, heart failure (HF) and bleeding complications.

Results

The incidences of in-hospital mortality according to quartiles from Q1 to Q4 were 8.6, 3.9, 2.4 and 2.6%, respectively (p < 0.001). The incidences of major hemorrhage and HF were significantly higher in Q1, compared to the other quartiles (7.4, 1.9, 3.1, 2.8%, p < 0.001; 16.3, 8.5, 7.7, 9.8%, p < 0.001, respectively). Multiple logistic-regression analysis showed that low admission Hb level (Q1) is an independent and a potent predictor for in-hospital mortality [unadjusted odds ratio (OR): 3.84, 95% confidence interval (CI): 1.78–7.82; p < 0.001].

Conclusion

Lower concentrations of Hb on admission are associated with higher rates of in-hospital mortality, heart failure and major bleeding after p-PCI.

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Conflict of interest

The authors have no conflict of interest to declare.

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Authors and Affiliations

  1. Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul, Turkey

    Cihan Dündar, Vecih Oduncu, Dicle Sırma, Ali Karagöz, Can Yücel Karabay, Alev Kılıçgedik, Selçuk Pala, Kürşat Tigen, Akın Izgi & Cevat Kırma

  2. Department of Cardiology, Kocaeli Derince Education and Research Hospital, İbni Sina Bulvarı, 41900, Derince, Kocaeli, Turkey

    Ayhan Erkol

  3. Department of Cardiology, Medicana International Hospital, Ankara, Turkey

    Ali Cevat Tanalp

Authors
  1. Cihan Dündar
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  2. Vecih Oduncu
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  3. Ayhan Erkol
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  4. Ali Cevat Tanalp
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  5. Dicle Sırma
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  6. Ali Karagöz
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  7. Can Yücel Karabay
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  8. Alev Kılıçgedik
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  9. Selçuk Pala
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  10. Kürşat Tigen
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  11. Akın Izgi
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  12. Cevat Kırma
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Corresponding author

Correspondence to Ayhan Erkol.

Additional information

This work was performed at Kartal Kosuyolu Heart Education and Research Hospital, Department of Cardiology, Istanbul, Turkey.

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Dündar, C., Oduncu, V., Erkol, A. et al. In-hospital prognostic value of hemoglobin levels on admission in patients with acute ST segment elevation myocardial infarction undergoing primary angioplasty. Clin Res Cardiol 101, 37–44 (2012). https://doi.org/10.1007/s00392-011-0361-9

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  • DOI: https://doi.org/10.1007/s00392-011-0361-9

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