Skip to main content

Advertisement

Log in

Heart failure, aging and beta-blockers: the need for more data on tolerability and efficacy

  • EDITORIAL
  • Published:
Clinical Research in Cardiology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Bohm M, Werner N, Kindermann M (2006) Drug treatment of chronic heart failure. Clin Res Cardiol 95(Suppl 4): 36–54

    Article  PubMed  Google Scholar 

  2. Dobre D, van Veldhuisen DJ, Mordenti G, et al. (2007) Tolerability and dose-related effects of nebivolol in elderly patients with heart failure: data from the study of the effects of nebivolol intervention on outcomes and rehospitalisation in seniors with heart failure (SENIORS) trial. Am Heart J 154:109–115

    Article  PubMed  CAS  Google Scholar 

  3. Düngen H, Krackhardt F, Apostolovic S, et al. (2008) Bisoprolol vs. Carvedilol in elderly patients with heart failure: rationale and desing of the CIBIS-ELD. Clin Res Cardiol This Issue

  4. Edes I, Gasior Z, Wita K (2005) Effects of nebivolol on left ventricular function in elderly patients with chronic heart failure: results of the ENECA study. Eur J Heart Fail 7:631–639

    Article  PubMed  CAS  Google Scholar 

  5. Flather MD, Shibata MC, Coats AJ, et al. (2005) Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS). Eur Heart J 26:215–225

    Article  PubMed  CAS  Google Scholar 

  6. Hillege HL, van Gilst WH, van Veldhuisen DJ, et al. (2003) Accelerated decline and prognostic impact of renal function after myocardial infarction and the benefits of ACE inhibition: the CATS randomized trial. Eur Heart J 24:412–420

    Article  PubMed  CAS  Google Scholar 

  7. Jaarsma T, van der Wal MH, Lesman-Leegte I, et al. (2008) Effect of moderate or intensive disease management program on outcome in patients with heart failure: coordinating study evaluating outcomes of advising and counseling in heart failure (COACH). Arch Intern Med 168:316–324

    Article  PubMed  Google Scholar 

  8. Kjekshus J, Apetrei E, Barrios V, et al. (2007) Rosuvastatin in older patients with systolic heart failure. N Engl J Med 357:2248–2261

    Article  PubMed  CAS  Google Scholar 

  9. Komajda M, Lapuerta P, Hermans N, et al. (2005) Adherence to guidelines is a predictor of outcome in chronic heart failure: the MAHLER survey. Eur Heart J 26:1653–1659

    Article  PubMed  Google Scholar 

  10. Kovacic D, Marinsek M, Gobec L, Lainscak M, Podbregar M (2008) Effect of selective and non-selective beta-blockers on body weight, insulin resistance and leptin concentration in chronic heart failure. Clin Res Cardiol 97:24–31

    Article  PubMed  CAS  Google Scholar 

  11. Krum H, Hill J, Fruhwald F, et al. (2006) Tolerability of beta-blockers in elderly patients with chronic heart failure: the COLA II study. Eur J Heart Fail 8:302–307

    Article  PubMed  CAS  Google Scholar 

  12. McAlister FA, Ezekowitz J, Tonelli M, Armstrong PW (2004) Renal insufficiency and heart failure: prognostic and therapeutic implications from a prospective cohort study. Circulation 109:1004–1009

    Article  PubMed  Google Scholar 

  13. McMurray JJ, Teerlink JR, Cotter G, et al. (2007) Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials. JAMA 298:2009–2019

    Article  PubMed  CAS  Google Scholar 

  14. Meinardi MT, van der Graaf WT, van Veldhuisen DJ, Gietema JA, De Vries EG, Sleijfer DT (1999) Detection of anthracycline-induced cardiotoxicity. Cancer Treat Rev 25:237–247

    Article  PubMed  CAS  Google Scholar 

  15. Neuberger HR, Mewis C, van Veldhuisen DJ, et al. (2007) Management of atrial fibrillation in patients with heart failure. Eur Heart J 28:2568–2577

    Article  PubMed  CAS  Google Scholar 

  16. Peters-Klimm F, Muller-Tasch T, Schellberg D, et al. (2008) Guideline adherence for pharmacotherapy of chronic systolic heart failure in general practice: a closer look on evidence-based therapy. Clin Res Cardiol 97:244–252

    Article  PubMed  CAS  Google Scholar 

  17. Poole-Wilson PA, Swedberg K, Cleland JG, et al. (2003) Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the carvedilol or metoprolol european trial (COMET): randomised controlled trial. Lancet 362:7–13

    Article  PubMed  CAS  Google Scholar 

  18. Sturm HB, Haaijer-Ruskamp FM, Veeger NJ, Balje-Volkers CP, Swedberg K, van Gilst WH (2006) The relevance of comorbidities for heart failure treatment in primary care: a European survey. Eur J Heart Fail 8:31–37

    Article  PubMed  Google Scholar 

  19. van der Wal MH, Jaarsma T, Moser DK, Veeger NJ, van Gilst WH, van Veldhuisen DJ (2006) Compliance in heart failure patients: the importance of knowledge and beliefs. Eur Heart J 27:434–440

    PubMed  Google Scholar 

  20. van Veldhuisen DJ, Aass H, El Allaf D, et al. (2006) Presence and development of atrial fibrillation in chronic heart failure. Experiences from the MERIT-HF study. Eur J Heart Fail 8:539–546

    Article  PubMed  Google Scholar 

  21. Willenheimer R, van Veldhuisen DJ, Silke B, et al. (2005) Effect on survival and hospitalization of initiating treatment for chronic heart failure with bisoprolol followed by enalapril, as compared with the opposite sequence: results of the randomized cardiac insufficiency bisoprolol study (CIBIS) III. Circulation 112:2426–2435

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

K. Damman (grant 2006B157), R.A. de Boer (grant 2004T004) and D.J. van Veldhuisen (grant D97-017) are all supported by the Netherlands Heart Foundation.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kevin Damman MD.

Additional information

Editorial to: “Bisoprolol vs carvedilol in elderly patients with heart failure: Rationale and design of the CIBIS-ELD”.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Damman, K., de Boer, R.A. & van Veldhuisen, D.J. Heart failure, aging and beta-blockers: the need for more data on tolerability and efficacy. Clin Res Cardiol 97, 575–577 (2008). https://doi.org/10.1007/s00392-008-0680-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00392-008-0680-7

Navigation