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Empfehlungen zur Diagnostik und Therapie der Schockformen der IAG Schock der DIVI

Teil 7: Besonderheiten im Kindesalter

  • MITTEILUNGEN DER DIVI
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Intensivmedizin und Notfallmedizin

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References

  1. Adams HA, Baumann G, Gänsslen A, Janssens U, Knoefel W, Koch T, Marx G, Müller-Werdan U, Pape HC, Prange H, Roesner D, Standl T, Teske W, Werner G, Zander R und die IAG Schock (2001) Die Definitionen der Schockformen. Intensivmed 38:541–553

    Google Scholar 

  2. Ashcraft KW (2000) Pediatric Surgery. WB Saunders, Philadelphia, pp 162–163

  3. Barnea O, Santamore WP, Rossi A, Salloum E, Chien S, Austin EH (1998) Estimation of oxygen delivery in newborns with a univentricular circulation. Circulation 98:1407–1413

    CAS  PubMed  Google Scholar 

  4. Barton P, Garcia J, Konathi A, Kitchen L, Zorka A, Lindsay C, Lawless S, Giroir B (1996) Hemodynamic effects of i.v. milrinone lactate in pediatric patients with septic shock. Chest 109:1302–1312

    CAS  PubMed  Google Scholar 

  5. Barton P, Kalil AC, Nadel S, Goldstein B, Okhysen-Cawley A, Brilli RJ, Takano JS, Martin LD, Quin P, Yeh TS, Dalton HJ, Gessouron MR, Brown KE, Betts H, Levin M, Macias WL, Small DS, Wyss VL, Bates BM, Utterbach BG, Giroir BP (2004) Safety, pharmacokinetics, and pharmacodynamics of drotrecogin alta (activated) in children with severe sepsis. Pediatrics 113:7–12

    Article  PubMed  Google Scholar 

  6. Baxter CR (1974) Fluid volume and electrolyte changes of the early postburn period. Clin Plastic Surg 1:693–709

    CAS  Google Scholar 

  7. Berman W jr, Wood SC, Yabek SM, Dillon T, Fripp RR, Burstein R (1987) Systemic oxygen transport in patients with congenital heart disease. Circulation 75:360–368

    PubMed  Google Scholar 

  8. Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ jr (Recombinant human protein C worldwide evaluation in severe sepsis (PROWESS) study group) (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344:699–709

    Article  CAS  PubMed  Google Scholar 

  9. Bohn DJ, Poirier CS, Edmonds JF, Barker GA (1980) Hemodynamic effects of dobutamine after cardiopulmonary bypass in children. Crit Care Med 8:367–371

    CAS  PubMed  Google Scholar 

  10. Bone RC, Fisher CJ, Clemmer TP, Slotman GJ, Metz CA, Balk RA (1987) A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N Engl J Med 317:653–658

    CAS  PubMed  Google Scholar 

  11. Briassoulin G, Narlioghan M, Zavras N, Hatzis T (2001) Myocardial injury in meningococcus-induced purpura fulminans in children. Intensive Care Med 27:1073–1082

    Google Scholar 

  12. Burns JP (2003) Septic shock in pediatric patients: Pathogenesis and novel treatment. Pediatr Emerg Care 19:115–115

    Article  Google Scholar 

  13. Butt W (2001) Septic shock. Pediatr Clin North Am 48:601–625

    Article  CAS  PubMed  Google Scholar 

  14. Chesnut RM, Gautille T, Blunt BA, Klauber MR, Marshall LF (1998) Neurogenic hypotension in patients with severe head injuries. J Trauma 44:958–963

    CAS  PubMed  Google Scholar 

  15. Cochrane injuries group albumin reviewers (1998) Human albumin administration in critically ill patients: systemic review of randomised controlled trials. BMJ 317:235–240

    Google Scholar 

  16. Cocks A J, O’Conell A, Martin H (1998) Crystalloids, colloids and kids: a review of paediatric burns in intensive care. Burn 24:717–724

    CAS  Google Scholar 

  17. Dasgupta SJ, Gill AB (2003) Hypotension in the very low birthweight infant: the old, the new, and the uncertain. Arch Dis Child 88:F450–F454

    CAS  Google Scholar 

  18. De Bruin WJ, Greenwald BM, Notterman DA (1992) Fluid resuscitation in pediatrics. Critical Care Clinics 8:423–438

    CAS  PubMed  Google Scholar 

  19. Evgenov OV, Bjertneaes LJ (2002) Administration of methylen blue in human septic shock: renaissance of an old drug? Crit Care Med 30:2271–2277

    Google Scholar 

  20. Fenichel GM (1993) Clinical pediatric neurology. WB Saunders, Philadelphia

  21. Fourrier F, Lestavel P, Chopin C, Marey A, Goudemand J, Rime A, Mangalaboji J (1990) Meningococcemia and purpura fulminans in adults: acute deficiencies of protein C and S and early treatment with antithrombin III concentrates. Intensive Care Med 16:121–124

    Article  CAS  PubMed  Google Scholar 

  22. Fu YC, Chi CS, Chiu YT, Hsu SL, Hwang B, Jan SL, Chen PY, Huang FL, Chang Y (2004) Cardiac complications of enterovirus rhombencephalitis. Arch Dis Child 89:368–373

    Article  CAS  PubMed  Google Scholar 

  23. Gaissmaier RE, Pohlandt F (1999) Single-dose dexamethasone treatment of hypotension in preterm infants. J Pediatr 134:701–705

    CAS  PubMed  Google Scholar 

  24. Goh A, Lum LCS (1999) Sepsis, severe sepsis and septic shock in paediatric multiple organ dysfunction syndrome. J Paediatr Child Health 35:448–492

    Google Scholar 

  25. Greenough A, Emery EF (1993) Randomised trial comparing dopamine and dobutamine in preterm infants. Eur J Pediatr 152:164–165

    Google Scholar 

  26. Hausdorf G (2000) Intensivtherapie angeborener Herzfehler. Steinkopff, Darmstadt

  27. Haze W (Hrsg) (1990) Verbrennungen im Kindesalter. Gustav Fischer, Stuttgart

  28. Hentschel R, Hensel D, Brune T, Rabe H, Jorch G (1995) Impact on blood pressure and intestinal perfusion of dobutamine or dopamine in hypotensive preterm infants. Biol Neonate 68:318–324

    CAS  PubMed  Google Scholar 

  29. Herrin JT (1990) Management of pediatric patients with burns. In: Inchikawa I (Ed) Pediatric textbook of fluids and electrolytes. Williams & Wilkins, Baltimore

  30. Illing S (2002) Anaphylaxie. In: Kretz FJ, Beushausen Th (Hrsg) Das Kinder Notfall Intensiv Buch. Urban & Fischer, München

  31. Jackson J, Bolte RG (2000) Risks of intravenous administration of hypotonic fluids for pediatric patients in ED and prehospital settings: Let’s remove the handle from the pump. Am J Emerg Med 18:269–270

    Article  CAS  PubMed  Google Scholar 

  32. Kimble KJ, Darnall RA, Yelderman MD (1981) An automated technique for estimating mean arterial pressure in critically ill newborns. Anesthesiology 54:423–425

    CAS  PubMed  Google Scholar 

  33. Kretz FJ, Beushausen Th (Hrsg) (2002) Das Kinder Notfall Intensiv Buch. Urban & Fischer, München

  34. Kulik Tj (1998) Pulmonary hypertension. In: Chang EC, Hanley FC, Wernowski (Eds) Pediatric cardiac intensive care. Williams & Wilkins, Baltimore, 497–506

  35. Leclerc F, Cremer R, Leteurtre S, Martinot A, Fourier C (2000) Protein C concentrate and recombinant tissue plasminogen activator in meningococcal septic shock. Crit Care Med 28:1694–1696

    CAS  PubMed  Google Scholar 

  36. Lefering R, Neugebauer EA (1995) Steroid controversy in sepsis and septic shock: a metaanalysis. Crit Care Med 23:1294–1303

    CAS  PubMed  Google Scholar 

  37. Leuchte H, Schwaiblmayer M, Baumgartner A, Neurohr CF, Kolbe T, Behr J (2004) Hemodynamic response to sildenafil, nitric oxide, and iloprost in primary pulmonary hypertension. Chest 125:580–586

    Article  CAS  PubMed  Google Scholar 

  38. Luedtke SA, Kuhn RJ, McCaffrey FM (1997) Pharmacological management of supraventricular tachycardias in children. Atrial flutter, atrial fibrillation, and junctional and atrial ectopic tachycardia. Ann Pharmacother 31:1227–1243

    CAS  PubMed  Google Scholar 

  39. Luedtke SA, Kuhn RJ, McCaffrey FM (1997) Pharmacological management of supraventricular tachycardias in children. Wolf–Parkonson-White and atrioventricular nodal reentry. Ann Pharmacother 31:1347–1359

    CAS  PubMed  Google Scholar 

  40. Macmillan CS, Grant IS, Andrews PJ (2002) Pulmonary and cardiac sequelae of subarachnoid haemorrhage: time for active management? Intensive Care Med 28:1012–1023

    CAS  PubMed  Google Scholar 

  41. Matok I, Leibovitch L, Vardi A (2004) Terlipressin as a rescue therapy for intractable hypotension during neonatal septic shock. Pediatr Crit Care Med 5:116–118

    PubMed  Google Scholar 

  42. Morelli A, Rocco M, Conti G, Orecchioni A, DeGaetano A, Cortese G, Coluzzi F, Vernaglione E, Pelaia P, Pietropaoli P (2003) Effects of terlipressin on systemic and regional haemodynamics in catecholamine-treated hyperkinetic septic shock. Intensive Care Med, Epub (http://www.springerlink.com)

  43. Nadas A (1993) Pediatric cardiology. Saunders, Philadelphia

  44. Nadel S, De Munter C, Britto J, Levin M, Habibi P (1998) Albumin: saint or sinner. Arch Dis Child 79:384–385

    CAS  PubMed  Google Scholar 

  45. Nahum E, Ben-Ari J, Schonfeld T (2004) Blood transfusion policy among european intensive care physicians. J Intensive Care Med 19:38–43

    Article  PubMed  Google Scholar 

  46. Ng PC, Lam CWK, Fok TF, Lee CH, Ma KC, Chan ICH, Wang E (2001) Refractory hypotension in preterm infants with adreno-cortical insufficiency. Arch Dis Child 84:F122-F124

    CAS  Google Scholar 

  47. Nicolai T (1999) Pädiatrische Notfall- und Intensivmedizin. Springer, Berlin

  48. Nowak-Göttl U, Groll A, Kreuz WD , Brand M, Breddin HK, von Loewenich V, Kornhuber B (1992) Behandlung der Verbrauchskoagulopathie mit Antithrombin-III-Konzentrat bei Kindern mit nachgewiesener Sepsis. Klin Pädiatr 204:134–140

    PubMed  Google Scholar 

  49. Nürnberger W, von Kries R, Bohm O, Gobel U (1999) Systemic meningococcal infection: which children may benefit from adjuvant haemostatic therapy? Results from an observational study. Eur J Pediatr 158 Suppl 3:S192–196

    Article  PubMed  Google Scholar 

  50. Nuntnarumit P, Yang W, Bada-Ellzey HS (1999) Blood pressure measurements in the newborn. Clin Perinatol 26:981–996

    CAS  PubMed  Google Scholar 

  51. Perry JC (1998) Pharmacologic management of arrhythmias. In: Deal JD, Wolff GS, Gelband H (Eds) Current concepts in diagnosis and management of arrhythmias in infants and children. Futura Publishing, New York, pp 267–308

  52. Peters MJ, Booth RA, Petros AJ (2004) Terlipressin bolus induces systemic vasoconstriction in septic shock. Pediat Crit Care Med 5:112–115

    Google Scholar 

  53. Pollard AJ, Britto J, Nadel S, De Munter C, Habibi P, Levin M (1999) Emergency management of meningococcal disease. Arch Dis Child 80:290–296

    CAS  PubMed  Google Scholar 

  54. Project team of the resuscitation council (UK) (1999) The emergency medical treatment of anaphylactic reactions. J Accid Emerg Med 16:243–247

    Google Scholar 

  55. Puffinbarger N K, Tuggle D W, Smith EI (1994) Rapid isotonic fluid resuscitation in pediatric thermal injury. J Pediat Surg 29:339–242

    Article  CAS  PubMed  Google Scholar 

  56. Raja NV, Maisels MJ, Kring E, Schwarz-Warner L (1999) Capillary refill time in the hands and feet of normal newborn infants. Clin Pediatr (Philadelphia) 38:139–144

    Google Scholar 

  57. Ringe HIG, Varnholt V, Gaedicke G (2003) Cardiac rescue with enoximone in volume and catecholamine refractory septic shock. Pediatr Crit Care Med 4:471–475

    PubMed  Google Scholar 

  58. Rodriguez-Nunez A, Fernandez-Sanmartin M, Martinon-Torres F, Gonzales-Alonso N, Martinon-Sanchez JM (2004) Terlipressin for catecholamine-resistent septic shock in children. Intensive Care Med 30:477–480

    PubMed  Google Scholar 

  59. Rogers MC, Helfaer MA (Eds) (1995) Handbook of pediatric intensive care. Williams & Wilkins, Baltimore

  60. Rosenstiel von N, Rosenstiel von I, Adam D (2001) Management of sepsis and septic shock in infants and children. Paediatr Drugs 3:9–27

    Google Scholar 

  61. Ruiz CE, Weit MH, Carlson RW (1979) Treatment of circulatory shock with dopamine. JAMA 165:242–246

    Google Scholar 

  62. Sae Lloms X, McCracken GH jr (1993) Sepsis syndrome and septic shock: Current concepts of terminology, pathophysiology and management. J Pediatr 123:497–508

    Google Scholar 

  63. Saudubray JM, Nassogne MC, de Lonlay P, Touati G (2002) Clinical approach to inherited metabolic disorders in neonates: an overview. Semin Neonatol 7:3–15

    CAS  PubMed  Google Scholar 

  64. Schaad UB, Lips U, Gnehm HE, Blumberg A, Heinzer I, Wedgwood J (1993) Dexamethasone therapy for bacterial meningitis in children. Swiss meningitis study group. Lancet 342:457–461

    Article  CAS  PubMed  Google Scholar 

  65. Schierhout G, Roberts I (1998) Fluid resuscitation with colloid or crystalloid solutions in critically ill patients: a systematic review of randomised trials. BMJ 316:961–964

    CAS  PubMed  Google Scholar 

  66. Schranz D und die Arbeitsgemeinschaft „Pulmonale Hypertension der Deutschen Gesellschaft für Pädiatrische Kardiologie (2003) Pulmonale Hypertension im Kindes- und Jugendalter. Monatsschr Kinderheilkunde 151:424–441

    Google Scholar 

  67. Sicherer SH, Forman JA, Noone SA (2000) Use assessment of self-administered epinephrine among food-allergic children and pediatricians. Pediatrics 105:359–362

    Article  CAS  PubMed  Google Scholar 

  68. Silka MJ (1998) Emergency management of arrhythmias. In: Deal JD, Wolff GS, Gelband H (Eds) Current concepts in diagnosis and management of arrhythmias in infants and children. Futura Publishing, New York, pp 309–328

  69. Simma B, Burger R, Falk M, Sacher P, Fanconi S (1998) A prospective, randomised, and controlled study of fluid management in children with severe head injury: lactated Ringer’s solution versus hypertonic saline. Crit Care Med 26:1265–1270

    CAS  PubMed  Google Scholar 

  70. Simons FE, Gu X, Johnston LM, Simons KJ (2000) Can epinephrine inhalations be substituted for epinephrine injection in children at risk for systemic anaphylaxis? Pediatrics 106:1040–1044

    Article  CAS  PubMed  Google Scholar 

  71. So KW, Fok TF, Ng PC, Wong WW, Cheung KL (1997) Randomised controlled trial of colloid or crystalloid in hypotensive preterm infants. Arch Dis Child 76:F 43–F 46

    CAS  Google Scholar 

  72. Sparrow A, Hedderley T, Nadel S (2002) Choice of fluid resuscitation of septic shock. Emerg Med J 19:114–116

    Article  CAS  PubMed  Google Scholar 

  73. Stevens RD, Bhardwaj A, Kirsch JR, Mirski MA (2003) Critical care and perioperative management in traumatic spinal cord injury. J Neurosurg Anesthesiol 15:215–229

    Article  PubMed  Google Scholar 

  74. Steward DJ (1995) Manual of pediatric anaesthesia. Churchill Livingstone, New York

  75. Stopfkuchen H, Queisser-Luft A, Vogel K (1990) Cardiovascular response to dobutamine determind by systolic time intervals in preterm infants. Crit Care Med 18:722–724

    CAS  PubMed  Google Scholar 

  76. Subhedar NV (2003) Treatment of hypotension in newborns. Semin Neonatol 8:413–423

    PubMed  Google Scholar 

  77. Tibby SM, Hatherill M, Murdoch IA (1999) Capillary refill time and coreperipheral temperature gap as indicators of haemodynamic status in pediatric intensive care patients. Arch Dis Child 80:163–166

    CAS  PubMed  Google Scholar 

  78. Vincent JL, Roman A, Kahn RJ (1990) Dobutamine administration in septic shock: addition to a standard protocol. Crit Care Med 18:689–693

    CAS  PubMed  Google Scholar 

  79. Walsh EP, Saul JP, Triedmann JK (2001) Cardiac arrhythmias in children and young adults with congenital heart disease. Lippincott Williams & Wilkins, Philadelphia

  80. Watkins AMC, West CR, Cooke RWI (1989) Blood pressure and cerebral haemorrhage and ischaemia in VLBW infants. Early Hum Dev 19:103–110

    Article  CAS  PubMed  Google Scholar 

  81. Yunge M, Petros A (2000) Angiotensin for septic shock unresponsive to noradrenaline. Arch Dis Child 82:388–389

    Article  CAS  PubMed  Google Scholar 

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Correspondence to H. A. Adams.

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Weitere, an der Erarbeitung der Empfehlungen beteiligte Mitglieder der IAG Schock: M. Bauer, Jena; A. Gänsslen, Hannover; R. Gärtner, München; C. Höflich, Berlin; J. A. Köppen, Hamburg; M. R. Raum, Köln; W. Schareck, Rostock; M. Wiersbitzky, Greifswald; A. Unterberg, Heidelberg; E. Yekebaş, Hamburg

Die Arbeitsgruppe wurde gefördert durch die Firmen B. Braun Melsungen AG, Fresenius Kabi Deutschland GmbH, Medtronic Deutschland GmbH und Porsche AG

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Adams, H.A., Baumann, G., Cascorbi, I. et al. Empfehlungen zur Diagnostik und Therapie der Schockformen der IAG Schock der DIVI. Intensivmed 43, 156–172 (2006). https://doi.org/10.1007/s00390-006-0580-x

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