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Propensity score analysis of postoperative and oncological outcomes after surgical treatment for splenic flexure colon cancer

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International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Purpose

The surgical treatment of splenic flexure colon cancer (SFCC) is somehow not yet well standardized. Postoperative and oncological results of the three surgical techniques most commonly used to treat SFCC: extended right colectomy (ERC), egmental left colectomy (SLC), and left colectomy (LC) were evaluated.

Methods

The study included all patients with stage I-III SFCC treated by ERC, SLC, or LC between 2005 and 2016. Postoperative and long-term outcomes after the different surgical techniques were analyzed: Propensity score matching (PSM) was performed to compare the outcomes between these surgical techniques and survival analyses were performed using the Kaplan-Meier method and log-rank tests.

Results

A total of 170 SFCC patients were operated; ERC was performed in 71 (41.76%), SLC in 36 (21.18%), and LC in 63 (37.06%). There were no significant differences in the short and long-term postoperative outcomes. Three comparison groups were developed so that PSM could be performed between the surgical technique cases: ERC (n = 59) vs. LC (n = 50); ERC (n = 50) vs. SLC (n = 33); and SLC (n = 32) vs. LC (n = 44). No differences in the short or long-term outcomes of these techniques were observed.

Conclusion

The short and long-term outcomes between ERC, SLC, and LC are similar. SLC should be considered oncologically as appropiate as the other more extensive resections.

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Authors and Affiliations

  1. Department of Surgery, University of Valencia, Valencia, Spain

    J. Martín Arévalo, D. Moro-Valdezate, S. A. García-Botello, V. Pla-Martí, M. Garcés-Albir, L. Pérez Santiago, A. Vargas-Durán & A. Espí-Macías

  2. Department of Surgery, Hospital Clínico Universitario de Valencia, Avda. Blasco Ibañez 17, 46010, Valencia, Spain

    J. Martín Arévalo, D. Moro-Valdezate, S. A. García-Botello, V. Pla-Martí, M. Garcés-Albir, L. Pérez Santiago, A. Vargas-Durán & A. Espí-Macías

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  1. J. Martín Arévalo
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Martín Arévalo, J., Moro-Valdezate, D., García-Botello, S.A. et al. Propensity score analysis of postoperative and oncological outcomes after surgical treatment for splenic flexure colon cancer. Int J Colorectal Dis 33, 1201–1213 (2018). https://doi.org/10.1007/s00384-018-3063-1

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