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A pooled analysis of en bloc right hemicolectomy with pancreaticoduodenectomy for locally advanced right-sided colon cancer

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Abstract

Purpose

The aim of this study was to evaluate the safety and efficacy of en bloc right hemicolectomy with pancreaticoduodenectomy (RHCPD) for locally advanced right-sided colon cancer (LARCC).

Method

A pooled data analysis was performed on individual patients identified from the literature and the authors’ institutions. The short- and long-term outcomes were assessed.

Results

Recruited in this study were 81 LARCC patients undergoing RHCPD, including 75 patients reported in the literature and 6 patients from our own institutions. R0 resection was achieved in 97.5% cases. Morbidity and the 30-day mortality rate were 53.8 and 3.7%, respectively. The median survival duration was 70.4 months, and the 1-, 3- and 5-year overall survival rates were 77.8, 64.6, and 55.2%, respectively. Multivariable analysis identified only lymph node metastasis (hazard ratio 3.474, 95% confidence interval 1.323–9.120; P = 0.011) as independent predictors of poor survival.

Conclusion

En bloc RHCPD for LARCC can be performed safely with a high proportion of R0 resection and a good postoperative survival outcome.

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Authors and Affiliations

  1. Department III of General Surgery, First Hospital of Lanzhou University, Lanzhou, China

    Debang Li

  2. Department of Hepatobiliary & Pancreatovascular Surgery, First Affiliated Hospital of Xiamen University, 55 Zhenhai Road, Xiamen, Fujian, 361003, China

    Xiaoying Si, Tao Wan & Yanming Zhou

Authors
  1. Debang Li
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  2. Xiaoying Si
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  3. Tao Wan
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  4. Yanming Zhou
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Corresponding author

Correspondence to Yanming Zhou.

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The authors declare that they have no conflict of interest.

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Li, D., Si, X., Wan, T. et al. A pooled analysis of en bloc right hemicolectomy with pancreaticoduodenectomy for locally advanced right-sided colon cancer. Int J Colorectal Dis 33, 819–822 (2018). https://doi.org/10.1007/s00384-018-2997-7

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  • DOI: https://doi.org/10.1007/s00384-018-2997-7

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