Skip to main content

Advertisement

Log in

Long-term risk of adenocarcinoma post-ileal pouch–anal anastomosis for ulcerative colitis: report of two cases and review of the literature

  • Case Report
  • Published:
International Journal of Colorectal Disease Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  1. Parks AG, Nicholls RJ (1978) Proctocolectomy without ileostomy for ulcerative colitis. Br Med J 2(6130):85–88

    Article  PubMed  CAS  Google Scholar 

  2. Heppell J, Weiland LH, Perrault J et al (1983) Fate of the rectal mucosa after rectal mucosectomy and ileoanal anastomosis. Dis Colon Rectum 26(12):768–771

    Article  PubMed  CAS  Google Scholar 

  3. O’Connell PR, Pemberton JH, Weiland LH et al (1987) Does rectal mucosa regenerate after ileoanal anastomosis? Dis Colon Rectum 30(1):1–5

    Article  PubMed  Google Scholar 

  4. Ravitch MM (1984) The reception of new operations. Ann Surg 200(3):231–246

    Article  PubMed  CAS  Google Scholar 

  5. Stern H, Walfisch S, Mullen B et al (1990) Cancer in an ileoanal reservoir: a new late complication? Gut 31(4):473–475

    Article  PubMed  CAS  Google Scholar 

  6. Puthu D, Rajan N, Rao R et al (1992) Carcinoma of the rectal pouch following restorative proctocolectomy. Report of a case. Dis Colon Rectum 35(3):257–260

    Article  PubMed  CAS  Google Scholar 

  7. Rodriguez-Sanjuan JC, Polavicja MG, Naranjo A et al (1995) Adenocarcinoma in an ileal pouch for ulcerative colitis. Dis Colon Rectum 38(7):779–780

    Article  PubMed  CAS  Google Scholar 

  8. Sequens R (1997) Cancer in the anal canal (transitional zone) after restorative proctocolectomy with stapled ileal pouch-anal anastomosis. Int J Colorectal Dis 12(4):254–255

    Article  PubMed  CAS  Google Scholar 

  9. Vieth M, Grunewald M, Niemeyer C et al (1998) Adenocarcinoma in an ileal pouch after prior proctocolectomy for carcinoma in a patient with ulcerative pancolitis. Virchows Arch 433(3):281–284

    Article  PubMed  CAS  Google Scholar 

  10. Iwama T, Kamikawa J, Higuchi T et al (2000) Development of invasive adenocarcinoma in a long-standing diverted ileal J-pouch for ulcerative colitis: report of a case. Dis Colon Rectum 43(1):101–104

    Article  PubMed  CAS  Google Scholar 

  11. Heuschen UA, Heuschen G, Autschbach F et al (2001) Adenocarcinoma in the ileal pouch: late risk of cancer after restorative proctocolectomy. Int J Colorectal Dis 16(2):126–130

    Article  PubMed  CAS  Google Scholar 

  12. Rotholtz NA, Pikarsky AJ, Singh JJ et al (2001) Adenocarcinoma arising from along the rectal stump after double-stapled ileorectal J-pouch in a patient with ulcerative colitis: the need to perform a distal anastomosis. Report of a case. Dis Colon Rectum 44(8):1214–1217

    Article  PubMed  CAS  Google Scholar 

  13. Hyman N (2002) Rectal cancer as a complication of stapled IPAA. Inflamm Bowel Dis 8(1):43–45

    Article  PubMed  Google Scholar 

  14. Laureti S, Ugolini F, D’Errico A et al (2002) Adenocarcinoma below ileoanal anastomosis for ulcerative colitis: report of a case and review of the literature. Dis Colon Rectum 45(3):418–421

    Article  PubMed  CAS  Google Scholar 

  15. Baratsis S, Hadjidimitriou F, Christodoulou M et al (2002) Adenocarcinoma in the anal canal after ileal pouch-anal anastomosis for ulcerative colitis using a double stapling technique: report of a case. Dis Colon Rectum 45(5):687–691, discussion 691–692

    Article  PubMed  Google Scholar 

  16. Bentrem DJ, Wang KL, Stryker SJ (2003) Adenocarcinoma in an ileal pouch occurring 14 years after restorative proctocolectomy: report of a case. Dis Colon Rectum 46(4):544–546

    Article  PubMed  Google Scholar 

  17. Hassan C, Zullo A, Speziale G et al (2003) Adenocarcinoma of the ileoanal pouch anastomosis: an emerging complication? Int J Colorectal Dis 18(3):276–278

    PubMed  Google Scholar 

  18. Negi SS, Chaudhary A, Gondal R (2003) Carcinoma of pelvic pouch following restorative proctocolectomy: report of a case and review of the literature. Dig Surg 20(1):63–65

    Article  PubMed  Google Scholar 

  19. Bell SW, Parry B, Neill M (2003) Adenocarcinoma in the anal transitional zone after ileal pouch for ulcerative colitis: report of a case. Dis Colon Rectum 46(8):1134–1137

    Article  PubMed  Google Scholar 

  20. Lee SW, Sonoda T, Milsom JW (2005) Three cases of adenocarcinoma following restorative proctocolectomy with hand-sewn anastomosis for ulcerative colitis: a review of reported cases in the literature. Colorectal Dis 7(6):591–597

    Article  PubMed  CAS  Google Scholar 

  21. Knupper N, Straub E, Terpe HJ et al (2006) Adenocarcinoma of the ileoanal pouch for ulcerative colitis—a complication of severe chronic atrophic pouchitis? Int J Colorectal Dis 21(5):478–482

    Article  PubMed  CAS  Google Scholar 

  22. Walker M, Radley S (2006) Adenocarcinoma in an ileoanal pouch formed for ulcerative colitis in a patient with primary sclerosing cholangitis and a liver transplant: report of a case and review of the literature. Dis Colon Rectum 49(6):909–912

    Article  PubMed  Google Scholar 

  23. Das P, Johnson MW, Tekkis PP et al (2007) Risk of dysplasia and adenocarcinoma following restorative proctocolectomy for ulcerative colitis. Colorectal Dis 9(1):15–27

    Article  PubMed  CAS  Google Scholar 

  24. Sagar P (2006) Adenocarcinoma in a pouch without a preceeding history of dysplasia. Colorectal Dis 8(6):526–527

    Article  PubMed  CAS  Google Scholar 

  25. Ota H, Yamazaki K, Endoh W et al (2007) Adenocarcinoma arising below an ileoanal anastomosis after restorative proctocolectomy for ulcerative colitis: report of a case. Surg Today 37(7):596–599

    Article  PubMed  Google Scholar 

  26. Chia CS, Chew MH, Chau YP et al (2008) Adenocarcinoma of the anal transitional zone after double stapled ileal pouch-anal anastomosis for ulcerative colitis. Colorectal Dis 10(6):621–623

    Article  PubMed  CAS  Google Scholar 

  27. Candioli S, Manigrasso A, Arcieri S et al (2007) Adenocarcinoma following restorative proctocolectomy for ulcerative colitis: a case report and review of the literature. G Chir 28(10):371–376

    PubMed  CAS  Google Scholar 

  28. Pedersen ME, Rahr HB, Fenger C et al (2008) Adenocarcinoma arising from the rectal stump eleven years after excision of an ileal J-pouch in a patient with ulcerative colitis: report of a case. Dis Colon Rectum 51(7):1146–1148

    Article  PubMed  Google Scholar 

  29. Naik VS, Patil SB, Scholefield J et al (2008) Adenocarcinoma arising in a background of chronic atrophic pouchitis in an ileoanal pouch for ulcerative colitis. Histopathology 53(3):354–358

    Article  PubMed  CAS  Google Scholar 

  30. Koh PK, Doumit J, Downs-Kelly E et al (2008) Ileo-anal j-pouch cancer: an unusual case in an unusual location. Tech Coloproctol 12(4):341–345

    Article  PubMed  CAS  Google Scholar 

  31. Branco BC, Sachar DB, Heimann T et al (2009) Adenocarcinoma following ileal pouch–anal anastomosis for ulcerative colitis: review of 26 cases. Inflamm Bowel Dis 15(2):295–299

    Article  PubMed  Google Scholar 

  32. Panier-Suffat L, Marracino M, Resegotti A et al (2009) Anal transitional zone adenocarcinoma following restorative proctocolectomy for ulcerative colitis: case report and review of literature. Acta Gastroenterol Belg 72(4):441–443

    PubMed  CAS  Google Scholar 

  33. Ault GT, Nunoo-Mensah JW, Johnson L et al (2009) Adenocarcinoma arising in the middle of ileoanal pouches: report of five cases. Dis Colon Rectum 52(3):538–541

    Article  PubMed  Google Scholar 

  34. Al-Sukhni W, McLeod RS, MacRae H et al (2010) Oncologic outcome in patients with ulcerative colitis associated with dyplasia or cancer who underwent stapled or handsewn ileal pouch-anal anastomosis. Dis Colon Rectum 53(11):1495–1500

    Article  PubMed  Google Scholar 

  35. Elkowitz D, Daum F, Markowitz J et al (2004) Risk factors for carcinoma of the pelvic ileal pouch/anal canal in ulcerative colitis. Ann Clin Lab Sci 34(2):143–149

    PubMed  Google Scholar 

  36. Duff SE, O’Dwyer ST, Hulten L et al (2002) Dysplasia in the ileoanal pouch. Colorectal Dis 4(6):420–429

    Article  PubMed  CAS  Google Scholar 

  37. Thompson-Fawcett MW, Mortensen NJ (1996) Anal transitional zone and columnar cuff in restorative proctocolectomy. Br J Surg 83(8):1047–1055

    Article  PubMed  CAS  Google Scholar 

  38. Thompson-Fawcett MW, Warren BF, Mortensen NJ (1998) A new look at the anal transitional zone with reference to restorative proctocolectomy and the columnar cuff. Br J Surg 85(11):1517–1521

    Article  PubMed  CAS  Google Scholar 

  39. Thompson-Fawcett MW, Marcus V, Redston M et al (2001) Risk of dysplasia in long-term ileal pouches and pouches with chronic pouchitis. Gastroenterology 12(2):275–281

    Article  Google Scholar 

Download references

Acknowledgments

Dr O’Riordan is supported by the Royal College of Surgeons in Ireland Travel Grant for 2010, The Postgraduate Traveling Fellowship in Surgery from Trinity College Dublin for 2009/2010, The Ethicon Foundation Travel Grant for 2010, and a travel grant from Covidien Ireland.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to James M. O’Riordan.

Additional information

Dr McLeod holds the Alfredo and Angelo De Gasperis Chair in Colorectal Cancer and Inflammatory Bowel Disease Research at the Zane Cohen Center for Digestive Diseases.

Rights and permissions

Reprints and permissions

About this article

Cite this article

O’Riordan, J.M., Kirsch, R., Mohseni, M. et al. Long-term risk of adenocarcinoma post-ileal pouch–anal anastomosis for ulcerative colitis: report of two cases and review of the literature. Int J Colorectal Dis 27, 405–410 (2012). https://doi.org/10.1007/s00384-011-1243-3

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00384-011-1243-3

Keywords

Navigation