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The long-term health-related quality of life in patients operated for choledochal cyst

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Pediatric Surgery International Aims and scope Submit manuscript

A Letter to the Editor to this article was published on 13 June 2019

Abstract

Purpose

Late postoperative complications in choledochal cyst (CC) patients are severe problems that affect the quality of life (QOL). We evaluated the postoperative complications and health-related QOL (HRQOL) of CC patients ≥ 18 years of age.

Methods

From April 1984 to January 2018, 114 CC patients underwent definitive surgery at our institution. Seventy-nine patients reached ≥ 18 years of age. The HRQOL was assessed using the Japanese version of the SF-36v2. Eight health domain (physical functioning, role-physical, body pain, general health, role-emotional, vitality, mental health, and social functioning) scores and three component summary [physical component summary, mental component summary (MCS), and role-social component summary] scores were compared between the patients with and without complications (C [+] vs. C [−]).

Results

Thirty-five patients answered the questionnaires. Twelve patients had postoperative complications. Among the eight domains, the score of general health was significantly lower in C [+] patients than in C [−] patients (p = 0.0488). Among the three component scores, the MCS score in C [+] patients was lower than in C [−] patients without significance (p = 0.0953).

Conclusions

The HRQOL of CC patients ≥ 18 years of age was mostly acceptable. However, postoperative complications can impair the sense of well-being and affect the mental health.

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References

  1. Lipsett PA, Pitt HA (2003) Surgical treatment of choledochal cysts. J Hepatobiliary Pancreat Surg 10:352–359. https://doi.org/10.1007/s00534-002-0797-4

    Article  PubMed  Google Scholar 

  2. Todani T, Watanabe Y, Urushihara N, Noda T, Morotomi Y (1995) Biliary complications after excisional procedure for choledochal cyst. J Pediatr Surg 30:478–481

    Article  CAS  PubMed  Google Scholar 

  3. Chijiiwa K, Tanaka M (1994) Late complications after excisional operation in patients with choledochal cyst. J Am Coll Surg 179:139–144

    CAS  PubMed  Google Scholar 

  4. Saing H, Han H, Chan KL, Lam W, Chan FL, Cheng W, Tam PK (1997) Early and late results of excision of choledochal cysts. J Pediatr Surg 32:1563–1566

    Article  CAS  PubMed  Google Scholar 

  5. Tsuchida Y, Takahashi A, Suzuki N, Kuroiwa M, Murai H, Toki F, Kawarasaki H, Hashizume K, Honna T (2002) Development of intrahepatic biliary stones after excision of choledochal cysts. J Pediatr Surg 37:165–167

    Article  PubMed  Google Scholar 

  6. Ohashi T, Wakai T, Kubota M, Matsuda Y, Arai Y, Ohyama T, Nakaya K, Okuyama N, Sakata J, Shirai Y, Ajioka Y (2013) Risk of subsequent biliary malignancy in patients undergoing cyst excision for congenital choledochal cysts. J Gastroenterol Hepatol 28:243–247. https://doi.org/10.1111/j.1440-1746.2012.07260.x

    Article  PubMed  PubMed Central  Google Scholar 

  7. Ono S, Fumino S, Shimadera S, Iwai N (2010) Long-term outcomes after hepaticojejunostomy for choledochal cyst: a 10- to 27-year follow-up. J Pediatr Surg 45:376–378. https://doi.org/10.1016/j.jpedsurg.2009.10.078

    Article  PubMed  Google Scholar 

  8. Soares KC, Kim Y, Spolverato G, Maithel S, Bauer TW, Marques H, Sobral M, Knoblich M, Tran T, Aldrighetti L, Jabbour N, Poultsides GA, Gamblin TC, Pawlik TM (2015) Presentation and clinical outcomes of choledochal cysts in children and adults: a multi-institutional analysis. JAMA Surg 150:577–584. https://doi.org/10.1001/jamasurg.2015.0226

    Article  PubMed  Google Scholar 

  9. Mukai M, Kaji T, Masuya R, Yamada K, Sugita K, Moriguchi T, Onishi S, Yamada W, Kawano T, Machigashira S, Nakame K, Takamatsu H, Ieiri S (2018) The long-term postoperative outcomes of choledochal cysts, focusing on the follow-up rate and late complications at a single institution. Surg Today 48:835–840

    Article  PubMed  Google Scholar 

  10. Fukuhara S, Bito S, Green J, Hsiao A, Kurokawa K (1998) Translation, adaptation, and validation of the SF-36 Health Survey for use in Japan. J Clin Epidemiol 51:1037–1044

    Article  CAS  Google Scholar 

  11. Fukuhara S, Ware JE Jr, Kosinski M, Wada S, Gandek B (1998) Psychometric and clinical tests of validity of the Japanese SF-36 Health Survey. J Clin Epidemiol 51:1045–1053

    Article  CAS  Google Scholar 

  12. Kanda Y (2013) Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics. Bone Marrow Transplant 48:452–458. https://doi.org/10.1038/bmt.2012.244

    Article  CAS  Google Scholar 

  13. Onishi S, Nakame K, Kaji T, Kawano M, Moriguchi T, Sugita K, Yano K, Nomura M, Yamada K, Yamada W, Masuya R, Kawano T, Machigashira S, Mukai M, Ieiri S (2017) The bowel function and quality of life of Hirschsprung disease patients who have reached 18 years of age or older—the long-term outcomes after undergoing the transabdominal soave procedure. J Pediatr Surg 52:2001–2005. https://doi.org/10.1016/j.jpedsurg.2017.08.036

    Article  PubMed  Google Scholar 

  14. Heistaro S, Jousilahti P, Lahelma E, Vartiainen E, Puska P (2001) Self rated health and mortality: a long term prospective study in eastern Finland. J Epidemiol Community Health 55:227–232

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Kaplan GA, Camacho T (1983) Perceived health and mortality: a nine-year follow-up of the human population laboratory cohort. Am J Epidemiol 117:292–304

    Article  CAS  PubMed  Google Scholar 

  16. Okamoto K, Tanaka Y (2004) Subjective usefulness and 6-year mortality risks among elderly persons in Japan. J Gerontol B Psychol Sci Soc Sci 59:246–249

    Article  Google Scholar 

  17. Versteegh HP, van Rooij IA, Levitt MA, Sloots CE, Wijnen RM, de Blaauw I (2013) Long-term follow-up of functional outcome in patients with a cloacal malformation: a systematic review. J Pediatr Surg 48:2343–2350. https://doi.org/10.1016/j.jpedsurg.2013.08.027

    Article  PubMed  Google Scholar 

  18. Guan G, Liu H, Wang Y, Han B, Jin Y (2014) Behavioural and emotional outcomes in school-aged children after surgery or transcatheter closure treatment for ventricular septal defect. Cardiol Young 24:910–917. https://doi.org/10.1017/s104795111300142x

    Article  PubMed  Google Scholar 

  19. Bell LE, Bartosh SM, Davis CL, Dobbels F, Al-Uzri A, Lotstein D, Reiss J, Dharnidharka VR (2008) Adolescent transition to adult care in solid organ transplantation: a consensus conference report. Am J Transplant 8:2230–2242. https://doi.org/10.1111/j.1600-6143.2008.02415.x

    Article  CAS  PubMed  Google Scholar 

  20. Clermonts S, van Loon YT, Wasowicz DK, Langenhoff BS, Zimmerman DDE (2018) Comparative quality of life in patients following transanal minimally invasive surgery and healthy control subjects. J Gastrointest Surg. https://doi.org/10.1007/s11605-018-3718-9

    Article  PubMed  Google Scholar 

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Acknowledgements

We thank Mr. Brian Quinn for his comments and help with the manuscript. This study was supported by a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science (JSPS, nos. 26670765, 16K10466, 16K10094, 16K10095, 16K10434, 16H07090, 17K10555, 17K11514, 17K10183, 17K11515), a Research Grant from the President’s Discretionary Expenses of our University, a Research Grant from The UBE Foundation, a Research Grant from Kawano Masanori Memorial Public Interest Incorporated Foundation for Promotion of Pediatrics, Research Grant from Tateishi Science and Technology Foundation, a Research Grant from Mitsui Life Social Welfare Foundation, and a Research Grant from The Kurata Grants of the Hitachi Global Foundation. Sponsor of Manuscript Submission: Atsuyuki Yamataka, M.D., Ph.D., F.A.A.P. (Hon), Department of Pediatric Surgery, Juntendo University, Tokyo, Japan.

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Authors and Affiliations

  1. Department of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan

    Tokuro Baba, Motoi Mukai, Ryuta Masuya, Masato Kawano, Keisuke Yano, Masakazu Murakami, Shun Onishi, Koji Yamada, Waka Yamada, Takafumi Kawano, Seiro Machigashira, Kazuhiko Nakame, Tatsuru Kaji & Satoshi Ieiri

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  1. Tokuro Baba
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  2. Motoi Mukai
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  3. Ryuta Masuya
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  4. Masato Kawano
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  12. Kazuhiko Nakame
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  13. Tatsuru Kaji
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  14. Satoshi Ieiri
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Correspondence to Satoshi Ieiri.

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Baba, T., Mukai, M., Masuya, R. et al. The long-term health-related quality of life in patients operated for choledochal cyst. Pediatr Surg Int 35, 539–546 (2019). https://doi.org/10.1007/s00383-019-04456-7

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  • DOI: https://doi.org/10.1007/s00383-019-04456-7

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