Skip to main content
SpringerLink
Log in

Congenital infantile fibrosarcoma of the colon: a case series and literature review

  • Case Report
  • Published:
Pediatric Surgery International Aims and scope Submit manuscript

Abstract

Congenital infantile fibrosarcoma is rare and only three cases affecting the colon have previously been reported. We describe two further cases that presented in the neonatal period and were both successfully treated with surgical excision and have no evidence of recurrence or metastasis at 31 and 27 months follow-up, respectively.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

References

  1. Moore SW, Satgé D, Sasco AJ, Zimmermann A, Plaschkes J (2003) The epidemiology of neonatal tumours. Report of an international working group. Pediatr Surg Int 19(7):509–519

    Article  PubMed  CAS  Google Scholar 

  2. Chung EB, Enzinger FM (1976) Infantile Fibrosarcoma. Cancer 38:729–739

    Article  PubMed  CAS  Google Scholar 

  3. Knezevich SR, McFadden DE, Tao W, Lim JF, Sorensen PH (1998) A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma. Nat Genet 18(2):184–187

    Article  PubMed  CAS  Google Scholar 

  4. Orbach D, Rey A, Cecchetto G, Oberlin O, Casanova M, Thebaud E, Scopinaro M, Bisogno G, Carli M, Ferrari A (2010) Infantile fibrosarcoma: management based on the European experience. J Clin Oncol 28(2):318–323

    Article  PubMed  Google Scholar 

  5. Nicholson JF, Pesce MA (2004) Reference ranges for laboratory tests and procedures. In: Behrman RE, Kliegman RM, Jenson HB (eds) Nelson textbook of paediatrics, 17th edn. Saunders, Philadelphia, pp 2396–2427

    Google Scholar 

  6. Blohm ME, Vesterling-Hörner D, Calaminus G, Göbel U (1998) Alpha 1-fetoprotein (AFP) reference values in infants up to 2 years of age. Pediatr Hematol Oncol 15(2):135–142

    Article  PubMed  CAS  Google Scholar 

  7. Buccoliero AM, Castiglione F, Rossi Degl’Innocenti D, Maio V, Taddei A, Sardi I, Noccioli B, Franchi A, Taddei GL (2008) Congenital/infantile fibrosarcoma of the colon: morphologic, immunohistochemical, molecular, and ultrastructural features of a relatively rare tumor in an extraordinary localization. J Pediatr Hematol Oncol 30(10):723–727

    Article  PubMed  CAS  Google Scholar 

  8. Islam S, Soldes OS, Ruiz R, Geiger JD (2008) Primary colonic congenital infantile fibrosarcoma presenting as meconium peritonitis. Pediatr Surg Int 24(5):621–623

    Article  PubMed  Google Scholar 

  9. Kim HY, Cho YH, Byun SY, Park KH (2013) A case of congenital infantile fibrosarcoma of sigmoid colon manifesting a pneumoperitoneum in a newborn. J Korean Med Sci 28(1):160–163

    Article  PubMed  PubMed Central  Google Scholar 

  10. McCahon E, Sorensen PH, Davis JH, Rogers PC, Schultz KR (2003) Non-resectable congenital tumors with the ETV6-NTRK3 gene fusion are highly responsive to chemotherapy. Med Pediatr Oncol 40(5):288–292

    Article  PubMed  Google Scholar 

  11. Lee MJ, Cairns RA, Munk PL, Poon PY (1996) Congenital-infantile fibrosarcoma: magnetic resonance imaging findings. Can Assoc Radiol J 47(2):121–125

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Neonatal Intensive Care Unit, Saint Mary’s Hospital, Manchester, UK

    Vijal Parmar & N. Edi-Osagie

  2. Department of Paediatric Surgery, Royal Manchester Children’s Hospital, Manchester, UK

    R. T. Peters & R. J. Craigie

  3. Department of Paediatric Histopathology, Royal Manchester Children’s Hospital, Manchester, UK

    E. Cheesman

  4. Manchester Academic Health Science Centre, University of Manchester, Manchester, UK

    N. Edi-Osagie & R. J. Craigie

Authors
  1. Vijal Parmar
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. T. Peters
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. Cheesman
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. Edi-Osagie
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. R. J. Craigie
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Vijal Parmar.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Parmar, V., Peters, R.T., Cheesman, E. et al. Congenital infantile fibrosarcoma of the colon: a case series and literature review. Pediatr Surg Int 30, 1079–1085 (2014). https://doi.org/10.1007/s00383-014-3589-4

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00383-014-3589-4

Keywords

Search

Navigation