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Treatment of venous malformations with ethanolamine oleate: a descriptive study of 83 cases

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Abstract

Purpose

To evaluate the outcome and complications of sclerotherapy with injection ethanolamine oleate for the treatment of venous malformations (VMs).

Methods

Eighty-three patients' (39 males and 44 females) age ranging from 3 months to 21 years with 85 lesions were followed clinically for about 1 year following treatment with injection of ethanolamine oleate. The cases were enrolled between January 2006 and December 2009. The amount of ethanolamine oleate per treatment session ranged from 0.50 to 10 ml, and maximum dose was 0.40 ml per kg body weight. All patients were evaluated after 8 weeks of last injection session. All of the treatment sessions were performed on a day-case basis.

Results

Eighty-five lesions have under gone 201 sclerotherapy sessions with 39 requiring one, 27 requiring two and 19 lesions requiring more than two sessions. Sclerotherapy with ethanolamine oleate provided complete resolution of symptoms in 79 lesions and significant improvement of 6 lesions. There is no recurrence of studied patients. All patients experienced pain and swelling to a variable degree for short duration. Skin sloughed out in four patients which were healed spontaneously. No other complications were observed in our study.

Conclusion

The treatment of VMs with injection ethanolamine oleate is safe and effective.

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Authors and Affiliations

  1. Department of Pediatric Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

    Shafiqul Hoque

  2. Department of Pediatric Surgery, ZH Sikder Women’s Medical College, Dhaka, Bangladesh

    Bijoy Krishna Das

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  1. Shafiqul Hoque
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  2. Bijoy Krishna Das
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Correspondence to Shafiqul Hoque.

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Hoque, S., Das, B.K. Treatment of venous malformations with ethanolamine oleate: a descriptive study of 83 cases. Pediatr Surg Int 27, 527–531 (2011). https://doi.org/10.1007/s00383-010-2824-x

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