Skip to main content

Advertisement

Log in

Congenital epulis of the jaw: a series of five cases and review of literature

  • Case Report
  • Published:
Pediatric Surgery International Aims and scope Submit manuscript

Abstract

This article describes five cases of congenital epulis, a rare and benign swelling in the mouth of a newborn, which is not widely known. We present five cases: four cases presented as single pedunculated nodules of the gingiva and in one case two nodules were present. Of all, 50% were located at the maxilla. Excision was performed in four of the five cases and in one case, spontaneous regression was awaited. No recurrence was reported. The characteristic features of congenital epulis are a pedunculated, flesh-pink coloured tumour with a predominant occurrence on the anterior maxillary alveolar ridge in a female newborn. Although the aetiology is unknown, most authors suggest a mesenchymal, rather than an odontogenic, origin. Endogenous hormonal factors might influence growth prenatally. Histological findings include granular cells with eosinophilic cytoplasm and small, eccentric nuclei. Despite the fact that the lesion can be a striking sight, spontaneous regression is possible and can be awaited. Indications for non-radical excision under local anaesthesia are severe upper airway obstruction and interference with feeding technique. In conclusion, we provide clinical and histological information about congenital epulis, so that this entity will be more easily recognised and relevant information given to parents.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Bilen BT, Alaybeyoglu N, Arslan A, Turkmen E, Aslan S, Celik M (2004) Obstructive congenital gingival granular cell tumour. Int J Pediatr Otorhinolaryngol 68:1567–1571. doi:10.1016/j.ijporl.2004.07.007

    Article  PubMed  Google Scholar 

  2. Canavan-Holliday KS, Lawson RA (2004) Anaesthetic management of the newborn with multiple congenital epulides. Br J Anaesth 93:742–744. doi:10.1093/bja/aeh255

    Article  PubMed  CAS  Google Scholar 

  3. Fister P, Volavsek M, Novosel SM, Jazbec J (2007) A newborn baby with a tumor protruding from the mouth. Diagnosis: congenital gingival granular cell tumor. Acta Dermatovenerol Alp Panonica Adriat 16:128–130

    PubMed  CAS  Google Scholar 

  4. Godra A, D’Cruz CA, Labat MF, Isaacson G (2004) Pathologic quiz case: a newborn with a midline buccal mucosa mass, congenital gingival granular cell tumor (congenital epulis). Arch Pathol Lab Med 128:585–586

    PubMed  Google Scholar 

  5. Lack EE, Worsham GF, Callihan MD, Crawford BE, Vawter GF (1981) Gingival granular cell tumors of the newborn (congenital “epulis”): a clinical and pathologic study of 21 patients. Am J Surg Pathol 5:37–46

    Article  PubMed  CAS  Google Scholar 

  6. Lapid O, Shaco-Levy R, Krieger Y, Kachko L, Sagi A (2001) Congenital epulis. Pediatrics 107:E22. doi:10.1542/peds.107.2.e22

    Article  PubMed  CAS  Google Scholar 

  7. Loyola AM, Gatti AF, Pinto DS Jr, Mesquita RA (1997) Alveolar and extra-alveolar granular cell lesions of the newborn: report of case and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 84:668–671. doi:10.1016/S1079-2104(97)90370-X

    Article  PubMed  CAS  Google Scholar 

  8. McGuire TP, Gomes PP, Freilich MM, Sandor GK (2006) Congenital epulis: a surprise in the neonate. J Can Dent Assoc 72:747–750

    PubMed  Google Scholar 

  9. Merrett SJ, Crawford PJ (2003) Congenital epulis of the newborn: a case report. Int J Paediatr Dent 13:127–129. doi:10.1046/j.1365-263X.2003.00435.x

    Article  PubMed  CAS  Google Scholar 

  10. Messina M, Severi FM, Buonocore G, Molinaro F, Amato G, Petraglia F (2006) Prenatal diagnosis and multidisciplinary approach to the congenital gingival granular cell tumor. J Pediatr Surg 41:E35–E38. doi:10.1016/j.jpedsurg.2006.07.003

    Article  PubMed  Google Scholar 

  11. Olson JL, Marcus JR, Zuker RM (2005) Congenital epulis. J Craniofac Surg 16:161–164. doi:10.1097/00001665-200501000-00033

    Article  PubMed  Google Scholar 

  12. Parmigiani S, Giordano G, Fellegara G, Brevi B, Magnani C (2004) A rare case of multiple congenital epulis. J Matern Fetal Neonatal Med 16(Suppl 2):55–58. doi:10.1080/14767050410001727224

    Article  PubMed  Google Scholar 

  13. Reinshagen K, Wessel LM, Roth H, Waag KL (2002) Congenital epulis: a rare diagnosis in paediatric surgery. Eur J Pediatr Surg 12:124–126. doi:10.1055/s-2002-30165

    Article  PubMed  CAS  Google Scholar 

  14. Sakai VT, Oliveira TM, Silva TC, Moretti AB, Santos CF, Machado MA (2007) Complete spontaneous regression of congenital epulis in a baby by 8 months of age. Int J Paediatr Dent 17:309–312. doi:10.1111/j.1365-263X.2006.00795.x

    Article  PubMed  Google Scholar 

  15. Silva GC, Vieira TC, Vieira JC, Martins CR, Silva EC (2007) Congenital granular cell tumor (congenital epulis): a lesion of multidisciplinary interest. Med Oral Patol Oral Cir Bucal 12:E428–E430

    PubMed  Google Scholar 

  16. Zuker RM, Buenechea R (1993) Congenital epulis: review of the literature and case report. J Oral Maxillofac Surg 51:1040–1043

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Peter Andriessen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Küpers, A.M., Andriessen, P., van Kempen, M.J.P. et al. Congenital epulis of the jaw: a series of five cases and review of literature. Pediatr Surg Int 25, 207–210 (2009). https://doi.org/10.1007/s00383-008-2304-8

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00383-008-2304-8

Keywords

Navigation