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Oral tumors and tumor-like lesions in infants and children

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Abstract

The aim of this retrospective study was to survey the spectrum of oral tumors and tumor-like lesions treated in a pediatric surgical unit. The clinical features and treatment outcome are presented, and guidelines for management discussed. Long-term follow-up was carried out both by re-examination and by means of a questionnaire. A total of 95 patients were encountered over a 30-year period. The age at presentation ranged from 1 day to 16 years, and the male to female ratio was 0.7:1. The lesions were located predominantly on the lips (22%), tongue (21%), and cheek (19%). Patients were divided into five groups based on histological diagnosis. Benign lesions accounted for 83 (87%) of the cases. Of these, 41 (43%) were benign tumors, the most common of which were the hemangiomas (17 cases). Hamartomas accounted for a further 22 benign lesions (23%), among which 12 were lymphangiomas. Furthermore, we saw 14 cases (15%) of mucoceles, ranula and dysontogenetic cysts, and a further 6 cases (6%) were classed as miscellaneous lesions. Simple surgical resection was successful in treating most benign lesions, with occasional re-excision being necessary in lymphangiomas. The long-term effects of treatment include reduction of the red volume of the lips, scarring following resection of parotid hemangiomas, a forked tongue after wedged resection, and partial facial nerve palsy. The group of 12 (13%) malignant tumors consisted of 5 rhabdomyosarcomas, 2 fibrosarcomas, 2 carcinomas of the parotid, 1 osteosarcoma, and 2 metastases. A multimodal approach was used in patients with rhabdomyosarcomas, while fibrosarcomas and parotid carcinomas were normally treated by surgical excision. Six of 12 patients with malignant tumors were alive after a median follow-up of 20.5 years. Re-examination of the malignant tumor group revealed scarring, impaired growth and function of the maxilla associated with local irradiation, and an external salivary fistula. In conclusion, while most oral and maxillofacial tumors of children are benign, malignant tumors of soft tissue, salivary glands and bones must be taken into account. There are specific aspects related to certain developmental and biological characteristics that make a mainly conservative approach preferable in these children.

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Authors and Affiliations

  1. Klinik und Poliklinik für Kinderchirurgie, Universitätsklinikum Leipzig AöR, Oststrasse 21–25, 04317 , Leipzig, Germany

    Ralf-Bodo Tröbs, Elinor Mader & Joachim Bennek

  2. Institut für Pathologie, Universitätsklinikum Leipzig AöR, 04317 , Leipzig, Germany

    Thomas Friedrich

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  1. Ralf-Bodo Tröbs
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  2. Elinor Mader
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  3. Thomas Friedrich
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  4. Joachim Bennek
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Correspondence to Ralf-Bodo Tröbs.

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Tröbs, RB., Mader, E., Friedrich, T. et al. Oral tumors and tumor-like lesions in infants and children. Ped Surgery Int 19, 639–645 (2003). https://doi.org/10.1007/s00383-003-0983-8

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