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Bradycardia without associated hypertension: a common sign of ventriculo-peritoneal shunt malfunction

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Abstract

Introduction

Delayed diagnosis of ventriculo-peritoneal (VP) shunt malfunction results in avoidable morbidity and mortality. One reason is that most of the signs of shunt malfunction have low specificity.

Objective

The objective of this study was to evaluate the presence of bradycardia as a sign of VP shunt malfunction in children with treated hydrocephalus.

Methods

Children presenting with clinical features suggestive of possible VP shunt malfunction were retrospectively identified. Children with confirmed shunt malfunction formed the study group. Those who did not have shunt malfunction formed the control group, and the symptoms and signs were compared between the two groups. In particular, the presence of bradycardia (a heart rate less than the second centile of age-related norms) was sought. The positive predictive value (PPV) of bradycardia was compared with other common features of shunt malfunction.

Results

Data were obtained for 52 patients: 34 in the study group (data from 40 admissions) and 18 controls. Bradycardia was present in 18 of 40 (45%) of the study group and 2 of 18(11%) controls (p = 0.011). Only two of the patients with bradycardia had associated hypertension. The PPV for bradycardia was 90% compared with 92% for reduced conscious level and 65% for both headache and vomiting (the four commonest presenting features).

Conclusions

Bradycardia without hypertension is common in children with VP shunt malfunction. The significance of bradycardia is often not recognised; the value of this sign should be emphasised.

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Authors and Affiliations

  1. Department of Paediatric Neurology, Brotherton Wing, Leeds General Infirmary, Leeds, LS1 3EX, UK

    John H. Livingston, Helen G. McCullagh & Anne-Marie Childs

  2. Department of Paediatrics, The Royal Hallamshire, Sheffield, S10 2JF, UK

    Gagan Kooner

  3. Department of Neurosurgery, Leeds General Infirmary, Leeds, LS1 3EX, UK

    Paul Chumas & Atul Tyagi

  4. Section of Epidemiology and Biostatistics, Leeds Institute of Molecular Medicine, Leeds, LS9 7TF, UK

    John C. Taylor

Authors
  1. John H. Livingston
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  2. Helen G. McCullagh
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  3. Gagan Kooner
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  4. Anne-Marie Childs
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  5. Paul Chumas
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  6. Atul Tyagi
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  7. John C. Taylor
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Corresponding author

Correspondence to John H. Livingston.

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Livingston, J.H., McCullagh, H.G., Kooner, G. et al. Bradycardia without associated hypertension: a common sign of ventriculo-peritoneal shunt malfunction. Childs Nerv Syst 27, 729–733 (2011). https://doi.org/10.1007/s00381-010-1315-7

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  • DOI: https://doi.org/10.1007/s00381-010-1315-7

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