Abstract
To compare antegrade versus retrograde recanalization, in terms of procedural time, radiation and contrast agent exposure, number and total length of implanted stents and procedural complications, in long and calcified, de novo femoropopliteal occlusions. We performed retrospective matching of prospectively acquired data by lesion length, occlusion length and lesion calcification by the peripheral arterial calcium scoring system (PACSS) score in patients who were referred for endovascular treatment due to symptomatic peripheral artery disease (PAD). Forty-two consecutive patients with antegrade and 23 patients with retrograde after failed antegrade recanalization were identified (mean lesion length = 32.1 ± 6.9 cm; mean occlusion length = 24.6 ± 7.7 cm; PACSS score = 3.25 ± 0.91). 23% of the patients had intermittent claudication, whereas 77% exhibited critical limb ischemia (CLI). Patients who underwent retrograde versus antegrade recanalization required a significantly lower number of stents (0.9 ± 1.0 versus 1.8 ± 1.4, p = 0.01) and a lower total stent length (6.8 ± 8.5 cm versus 11.7 ± 9.9 cm, p < 0.05) in the interest of more extensive coverage of the lesions using drug coated balloons (DCB) (28.5 ± 12.0 cm versus 18.2 ± 16.0 cm, p = 0.01). No re-entry device was required with the retrograde versus 9 of 42 (21%) with the antegrade recanalization group (p = 0.02). The rate of complications due to retrograde puncture was low (one patient with hematoma and one with distal pseudoaneurysm, both managed conservatively). In long and calcified femoropopliteal occlusions, the retrograde approach is associated with a lower number of re-entry devices and stents and with more extensive lesion coverage with DCB, in the interest of costs and possibly long-term patency.
German Clinical Trials Register: DRKS00015277.
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Abbreviations
- CAD:
-
Coronary artery disease
- CFA:
-
Common femoral artery
- CLI:
-
Critical limb ischemia
- DCB:
-
Drug coated balloons
- GFR:
-
Glomerular filtration rate
- HsTnT:
-
Highly sensitive troponin T
- PAD:
-
Peripheral artery disease
- PACSS:
-
Peripheral arterial calcium scoring system
- SFA:
-
Superficial femoral artery
- TASC:
-
Transatlantic Intersociety Consensus
References
Gallino A, Aboyans V, Diehm C, Cosentino F, Stricker H, Falk E, Schouten O, Lekakis J, Amann-Vesti B, Siclari F, Poredos P, Novo S, Brodmann M, Schulte KL, Vlachopoulos C, De Caterina R, Libby P, Baumgartner I, European Society of Cardiology Working Group on Peripheral Circulation (2014) Non-coronary atherosclerosis. Eur Heart J 35(17):1112–1119
Fowkes FGR, Rudan D, Rudan I, Aboyans V, Denenberg JO, McDermott MM, Norman PE, Sampson UK, Williams LJ, Mensah GA, Criqui MH (2013) Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis. Lancet 382(9901):1329–1340
Bradbury AW, Adam DJ, Bell J, Forbes JF, Fowkes FGR, Gillespie I, Ruckley CV, Raab GM, BASIL trial Participants (2010) Bypass versus angioplasty in severe ischaemia of the leg (BASIL) trial: an intention-to-treat analysis of amputation-free and overall survival in patients randomized to a bypass surgery-first or a balloon angioplasty-first revascularization strategy. J Vasc Surg 51(5 Suppl):5S–17S
Fakhry F, Spronk S, van der Laan L, Wever JJ, Teijink JAW, Hoffmann WH, Smits TM, van Brussel JP, Stultiens GN, Derom A, den Hoed PT, Ho GH, van Dijk LC, Verhofstad N, Orsini M, van Petersen A, Woltman K, Hulst I, van Sambeek MR, Rizopoulos D, Rouwet EV, Hunink MG (2015) Endovascular revascularization and supervised exercise for peripheral artery disease and intermittent claudication: a randomized clinical trial. JAMA 314(18):1936–1944
Greenhalgh RM, Belch JJF, Brown LC, Gaines PA, Gao L, Reise JA, Thompson SG, Mimic trial Participants (2008) The adjuvant benefit of angioplasty in patients with mild to moderate intermittent claudication (MIMIC) managed by supervised exercise, smoking cessation advice and best medical therapy: results from two randomised trials for stenotic femoropopliteal and aortoiliac arterial disease. Eur J Vasc Endovasc Surg 36(6):680–688
Agarwal S, Sud K, Shishehbor MH (2016) Nationwide trends of hospital admission and outcomes among critical limb ischemia patients: from 2003–2011. J Am Coll Cardiol 67(16):1901–1913
Aboyans V, Ricco J-B, Bartelink M-LEL, Björck M, Brodmann M, Cohnert T, Aboyans V, Ricco JB, Bartelink MEL, Björck M, Brodmann M, Cohnert T, Collet JP, Czerny M, De Carlo M, Debus S, Espinola-Klein C, Kahan T, Kownator S, Mazzolai L, Naylor AR, Roffi M, Röther J, Sprynger M, Tendera M, Tepe G, Venermo M, Vlachopoulos C, Desormais I, ESC Scientific Document Group (2018) 2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteriesEndorsed by: the European Stroke Organization (ESO)The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the European Society of Cardiology (ESC) and of the European Society for Vascular Surgery (ESVS). Eur Heart J 39(9):763–816
Bhatt H, Kovach R, Janzer S, George JC (2018) SUPERA stent outcomes in Above-The-Knee IntervEntions: effects of COMPression and ELongation (SAKE-COMPEL) Sub-study. Cardiovasc Revasc Med 19(5 Pt A):512–515
Scheinert D, Laird JR, Schröder M, Steinkamp H, Balzer JO, Biamino G (2001) Excimer laser-assisted recanalization of long, chronic superficial femoral artery occlusions. J Endovasc Ther 8(2):156–166
Montero-Baker M, Schmidt A, Bräunlich S, Ulrich M, Thieme M, Biamino G, Botsios S, Bausback Y, Scheinert D (2008) Retrograde approach for complex popliteal and tibioperoneal occlusions. J Endovasc Ther 15(5):594–604
Jacobs DL, Motaganahalli RL, Cox DE, Wittgen CM, Peterson GJ (2006) True lumen re-entry devices facilitate subintimal angioplasty and stenting of total chronic occlusions: Initial report. J Vasc Surg 43(6):1291–1296
Schmidt A, Bausback Y, Piorkowski M, Werner M, Bräunlich S, Ulrich M, Varcoe R, Friedenberger J, Schuster J, Botsios S, Scheinert D (2012) Retrograde recanalization technique for use after failed antegrade angioplasty in chronic femoral artery occlusions. J Endovasc Ther 19(1):23–29
Walker CM, Mustapha J, Zeller T, Schmidt A, Montero-Baker M, Nanjundappa A, Manzi M, Palena LM, Bernardo N, Khatib Y, Beasley R, Leon L, Saab FA, Shields AR, Adams GL (2016) Tibiopedal access for crossing of infrainguinal artery occlusions: a prospective multicenter observational study. J Endovasc Ther 23(6):839–846
Diaz-Sandoval LJ, Soukas PA (2013) Popliteal arterial access. In: Dieter RS, Dieter RA Jr, Dieter RA III (eds) Endovascular interventions: a case-based approach. Springer, New York, pp 645–658
Dattilo R, Himmelstein SI, Cuff RF (2014) The COMPLIANCE 360° Trial: a randomized, prospective, multicenter, pilot study comparing acute and long-term results of orbital atherectomy to balloon angioplasty for calcified femoropopliteal disease. J Invasive Cardiol 26(8):355–360
Fanelli F, Cannavale A, Gazzetti M, Lucatelli P, Wlderk A, Cirelli C, d'Adamo A, Salvatori FM (2014) Calcium burden assessment and impact on drug-eluting balloons in peripheral arterial disease. Cardiovasc Intervent Radiol 37(4):898–907
Montero-Baker M (2014) The retrograde approach for BTK chronic total occlusions. Endovasc Today 5:55–64
El-Sayed HF (2013) Retrograde pedal/tibial artery access for treatment of infragenicular arterial occlusive disease. Methodist DeBakey Cardiovasc J 9(2):73–78
Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FGR (2007) Inter-society consensus for the management of peripheral arterial disease (TASC II). J Vasc Surg 45(1):S5–67
Fujihara M, Takahara M, Sasaki S, Nanto K, Utsunomiya M, Iida O, Yokoi Y (2017) Angiographic dissection patterns and patency outcomes after balloon angioplasty for superficial femoral artery disease. J Endovasc Ther 24(3):367–375
Armstrong EJ, Brodmann M, Deaton DH, Gray WA, Jaff MR, Lichtenberg M, Rundback JH, Schneider PA (2019) Dissections after infrainguinal percutaneous transluminal angioplasty: a systematic review and current state of clinical evidence. J Endovasc Ther 26(4):479–489
Touma G, Ramsay D, Weaver J (2015) Chronic total occlusions—current techniques and future directions. IJC Heart Vasc 1(7):28–39
Tønnesen KH, Sager P, Karle A, Henriksen L, Jørgensen B (1988) Percutaneous transluminal angioplasty of the superficial femoral artery by retrograde catheterization via the popliteal artery. Cardiovasc Intervent Radiol 11(3):127–131
Malyar N, Fürstenberg T, Wellmann J, Meyborg M, Lüders F, Gebauer K, Bunzemeier H, Roeder N, Reinecke H (2013) Recent trends in morbidity and in-hospital outcomes of in-patients with peripheral arterial disease: a nationwide population-based analysis. Eur Heart J 34(34):2706–2714
Matsi PJ, Manninen HI, Söder HK, Mustonen P, Kouri J (1995) Percutaneous transluminal angioplasty in femoral artery occlusions: primary and long-term results in 107 claudicant patients using femoral and popliteal catheterization techniques. Clin Radiol 50(4):237–244
Noory E, Rastan A, Schwarzwälder U, Sixt S, Beschorner U, Bürgelin K, Neumann FJ, Zeller T (2009) Retrograde transpopliteal recanalization of chronic superficial femoral artery occlusion after failed re-entry during antegrade subintimal angioplasty. J Endovasc Ther 16(5):619–623
Evans C, Peter N, Gibson M, Torrie EP, Galland RB, Magee TR (2010) Five-year retrograde transpopliteal angioplasty results compared with antegrade angioplasty. Ann R Coll Surg Engl 92(4):347–352
Chin H’ng MW, Punamiya S (2014) An innovative modification of the retrograde approach to angioplasty and recanalization of the superficial femoral artery. Diagn Interv Radiol Ank Tur 20(2):164–167
Yilmaz S, Altinbaş H, Senol U, Sindel T, Mete A, Lüleci E (2002) Common peroneal nerve palsy after retrograde popliteal artery puncture. Eur J Vasc Endovasc Surg 23(5):467–469
McCullough KM (1993) Retrograde transpopliteal salvage of the failed antegrade transfemoral angioplasty. Australas Radiol 37(4):329–331
Kaushal A, Roche-Nagle G, Tan KT, Liao E, Eisenberg N, Oreopoulos GD, Rajan DK (2018) Outcomes at a single center after subintimal arterial flossing with antegrade-retrograde intervention for critical limb ischemia. J Vasc Surg 67(5):1448–1454
Venkatachalam S, Bunte M, Monteleone P, Lincoff A, Maier M, Shishehbor MH (2014) Combined antegrade-retrograde intervention to improve chronic total occlusion recanalization in high-risk critical limb ischemia. Ann Vasc Surg 28(6):1439–1448
Scheinert D, Bräunlich S, Scheinert S, Ulrich M, Biamino G, Schmidt A (2005) Initial clinical experience with an IVUS-guided transmembrane puncture device to facilitate recanalization of total femoral artery occlusions. EuroIntervention 1(1):115–119
Shanmugasundaram M, Murugapandian S, Truong HT, Lotun K, Banerjee S (2018) Drug coated balloon in peripheral artery disease. Cardiovasc Revasc Med 20(4):338–343
Korosoglou G, Lichtenberg M, Celik S, Andrassy J, Brodmann M, Andrassy M (2018) The evolving role of drug-coated balloons for the treatment of complex femoropopliteal lesions. J Cardiovasc Surg (Torino) 59(1):51–59
Saab F, Jaff MR, Diaz-Sandoval LJ, Engen GD, McGoff TN, Adams G, Al-Dadah A, Goodney PP, Khawaja F, Mustapha JA (2018) Chronic total occlusion crossing approach based on plaque cap morphology: the CTOP classification. J Endovasc Ther 25(3):284–921
Korosoglou G, Eisele T, Raupp D, Eisenbach C, Giusca S (2017) Successful recanalization of long femoro-crural occlusive disease after failed bypass surgery. World J Cardiol 9(12):842–847
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Giusca, S., Lichtenberg, M., Hagstotz, S. et al. Comparison of ante-versus retrograde access for the endovascular treatment of long and calcified, de novo femoropopliteal occlusive lesions. Heart Vessels 35, 346–359 (2020). https://doi.org/10.1007/s00380-019-01498-8
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DOI: https://doi.org/10.1007/s00380-019-01498-8