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Changes in glucose, glycogen, thyroid activity and hypothalamic catecholamines in tench by starvation and refeeding

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Abstract

The effects of short-term food deprivation (7 days) and refeeding (2 days) on different biochemical and neuroendocrine parameters were studied in tench. A 7-days fast resulted in a significant reduction of plasma glucose and glycogen hepatic content, supporting the key role of liver glycogen as energy depot for being consumed during fasting. The rapid recovery of normal values of blood glucose and glycogen stores by refeeding indicates a rapid replenishment of liver glycogen stores. The short-term starvation decreased circulating thyroid hormones (both T3 and T4) and T4 release from thyroid, supporting an interaction between nutritional state and thyroid function in tench. All these metabolic and hormonal changes were partial or totally reversed under refeeding conditions. An increase in hypothalamic content of norepinephrine and dopamine was found in fasted fish. This result might be a consequence of stress induced by starvation.

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Fig. 1.
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Abbreviations

bw:

body weight

DA:

dopamine

DHBA:

3,4-dihydroxybenzilamine

E:

epinephrine

HSI:

hepatosomatic index

NE:

norepinephrine

T3 :

3',5,3,-triiodothyronine

T4 :

thyroxine

TH:

thyroid hormones

TSH:

thyroid-stimulating hormone

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Acknowledgements

This research was supported by AGL2001-0593-C03-03. Tench were kindly provided by "Centro Regional de Acuicultura. Piscifactoría Las Vegas del Guadiana" (Badajoz, Spain). Experiments performed in this study comply with the current laws of Spain.

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Authors and Affiliations

  1. Departamento de Fisiología Animal, Facultad de Ciencias Biológicas, Universidad Complutense, 28040, Madrid, Spain

    N. De Pedro, M. J. Delgado, B. Gancedo & M. Alonso-Bedate

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  1. N. De Pedro
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  2. M. J. Delgado
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  3. B. Gancedo
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  4. M. Alonso-Bedate
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Correspondence to N. De Pedro.

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Communicated by: G. Heldmaier

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De Pedro, N., Delgado, M.J., Gancedo, B. et al. Changes in glucose, glycogen, thyroid activity and hypothalamic catecholamines in tench by starvation and refeeding. J Comp Physiol B 173, 475–481 (2003). https://doi.org/10.1007/s00360-003-0355-7

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