Zusammenfassung
Interferon (IFN)-β wird zur Behandlung einer multiplen Sklerose eingesetzt. Unter dieser Therapie können thromboembolische Komplikationen auftreten. Wir berichten von einer Patientin, bei der sich nach 10-jähriger IFN-β-Behandlung eine venöse Staseretinopathie in Kombination mit Arterienastverschlüssen entwickelte. Thromboembolische und kardiovaskuläre Risikofaktoren, die für das Ereignis verantwortlich sein könnten, wurden ausgeschlossen. Das Auftreten eines kombinierten Gefäßverschlusses lässt somit einen Zusammenhang zur langjährigen Therapie mit IFN-β vermuten.
Abstract
Interferon (IFN) beta is commonly used in the treatment of multiple sclerosis. Thromboembolic complications may be associated with this therapy. We describe a case of branch arterial occlusions combined with central vein occlusion in a female patient who had undergone IFN beta therapy for 10 years. Thromboembolic and cardiovascular risk factors responsible for this event were excluded. The appearance of retinal vein and artery occlusions in our patient indicates an association with the long-term use of IFN beta.
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Jenisch, T., Dietrich-Ntoukas, T., Renner, A. et al. Kombinierter retinaler arteriovenöser Verschluss unter Interferon-β-Therapie. Ophthalmologe 109, 71–75 (2012). https://doi.org/10.1007/s00347-011-2448-0
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DOI: https://doi.org/10.1007/s00347-011-2448-0