Skip to main content

Advertisement

Log in

Outcomes of octogenarians undergoing holmium laser enucleation of prostate

  • Original Article
  • Published:
World Journal of Urology Aims and scope Submit manuscript

Abstract

Purpose

Holmium laser enucleation of prostate (HoLEP) is an effective surgical procedure in men with BPH. Due to the increase in the use of medical therapy for BPH related lower urinary symptoms more octogenarians are presenting in a delayed fashion with significant symptoms and urinary retention. We evaluate the feasibility and safety of octogenarians undergoing HoLEP.

Methods

We performed a retrospective review of HoLEPs at our institution from July 2018 to December 2019. Patients were stratified into two groups based on age: < 80 and ≥ 80.

Results

A total of 458 patients were identified, with 74 (16.2%) ≥ 80. In patients ≥ 80, prostate volume was higher (p < 0.0005), there was a higher rate of antiplatelet/anticoagulation (p = 0.029) use, and a lower rate of alpha-blocker use (p = 0.0016). As expected, ASA scores which correlate with increasing number of concomitant diseases were greater in the ≥ 80 cohort (p = 0.016). There was no significant difference in intraoperative complications (p = 0.14), 90 day complication (p = 0.34), readmission rates (p = 0.425) or emergency room visits between groups (p = 0.15).

Conclusions

Despite higher medical comorbidities and increased rates of anticoagulation in octogenarians, there is no increase in operative or postoperative complication rates. Age alone should not be used as exclusion criteria for HoLEP.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Egan KB (2016) The epidemiology of benign prostatic hyperplasia associated with lower urinary tract symptoms: prevalence and incident rates. Urol Clin North Am 43(3):289–297. https://doi.org/10.1016/j.ucl.2016.04.001

    Article  PubMed  Google Scholar 

  2. Lim KB (2017) Epidemiology of clinical benign prostatic hyperplasia. Asian J Urol 4(3):148–151. https://doi.org/10.1016/j.ajur.2017.06.004

    Article  PubMed  PubMed Central  Google Scholar 

  3. Elshal AM, Elmansy HM, Elhilali MM (2013) Transurethral laser surgery for benign prostate hyperplasia in octogenarians: safety and outcomes. Urology 81(3):634–639. https://doi.org/10.1016/j.urology.2012.11.042

    Article  PubMed  Google Scholar 

  4. Nadu A et al (2004) Are indications for prostatectomy in octogenarians the same as for younger men? Int Urol Nephrol 36(1):47–50. https://doi.org/10.1023/b:urol.0000032683.36827.63

    Article  PubMed  Google Scholar 

  5. Cornu JN et al (2015) A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: an update. Eur Urol 67(6):1066–1096. https://doi.org/10.1016/j.eururo.2014.06.017

    Article  PubMed  Google Scholar 

  6. Large T et al (2020) Comparative study of holmium laser Enucleation of the prostate with MOSES enabled pulsed laser modulation. Urology 136:196–201. https://doi.org/10.1016/j.urology.2019.11.029

    Article  PubMed  Google Scholar 

  7. Large T, Krambeck AE (2018) Evidence-based outcomes of holmium laser enucleation of the prostate. Curr Opin Urol 28(3):301–308. https://doi.org/10.1097/MOU.0000000000000498

    Article  PubMed  Google Scholar 

  8. Fitzpatrick JM (2006) The natural history of benign prostatic hyperplasia. BJU Int 97(S2):3–6. https://doi.org/10.1111/j.1464-410X.2006.06097.x

    Article  PubMed  Google Scholar 

  9. Piao S et al (2016) Holmium laser enucleation of the prostate is safe for patients above 80 years: a prospective study. Int Neurourol J 20(2):143–150. https://doi.org/10.5213/inj.1630478.239

    Article  PubMed  PubMed Central  Google Scholar 

  10. Tamalunas A et al (2020) The clinical value of holmium laser enucleation of the prostate in octogenarians. LUTS 13(2):279–285. https://doi.org/10.1111/luts.12366

    Article  CAS  PubMed  Google Scholar 

  11. Descazeaud A et al (2009) Laser treatment of benign prostatic hyperplasia in patients on oral anticoagulant therapy: a review. BJU Int 103(9):1162–1165. https://doi.org/10.1111/j.1464-410X.2008.08284.x

    Article  PubMed  Google Scholar 

  12. Foster HE et al (2018) Surgical management of lower urinary tract symptoms attributed to benign prostatic hyperplasia: AUA guideline. J Urol 200(3):612–619. https://doi.org/10.1016/j.juro.2018.05.048

    Article  PubMed  Google Scholar 

  13. El Tayeb MM et al (2016) Holmium laser enucleation of the prostate in patients requiring anticoagulation. J Endourol 30(7):805–809. https://doi.org/10.1089/end.2016.0070

    Article  PubMed  Google Scholar 

  14. Rivera M, Krambeck A, Lingeman J (2017) Holmium laser enucleation of the prostate in patients requiring anticoagulation. Curr Urol Rep 18(10):77. https://doi.org/10.1007/s11934-017-0727-2

    Article  PubMed  Google Scholar 

  15. Mmeje CO et al (2013) Age-stratified outcomes of holmium laser enucleation of the prostate. BJU Int 112(7):982–989. https://doi.org/10.1111/bju.12063

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

JH: project development, data collection, manuscript writing. DA: data collection, manuscript writing/editing, protocol/project development. SK: manuscript writing. CN: protocol/project development, data collection/management. TL: protocol/project development, data collection/management. AK: protocol/project development, data analysis, manuscript writing/editing. MR: protocol/project development, data analysis, manuscript writing/editing.

Corresponding author

Correspondence to Joshua Heiman.

Ethics declarations

Conflict of interest

AEK—paid consultant for Lumenis and Boston Scientific. No other authors have disclosures.

Ethical approval

Appropriate Institutional Review Board approval was obtained for this retrospective review.

Informed consent

An informed consent waiver was approved due to the retrospective nature of this research.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Heiman, J., Agarwal, D., Komanapalli, S. et al. Outcomes of octogenarians undergoing holmium laser enucleation of prostate. World J Urol 40, 1751–1754 (2022). https://doi.org/10.1007/s00345-022-04053-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00345-022-04053-9

Keywords

Navigation